Participants n | 52 | 36 | 23 | 6 |
Respiratory measures | | | | |
Respiratory events n | | | | |
T0 | 9.56±5.32 | 51.44±32.37 | 131.13±130.60 | 173.0±115.15 |
T1 | 14.60±18.69¶ | 28.14±27.89# | 24.39±24.71# | 16.50±34.07¶ |
Central apnoeas n | | | | |
T0 | 0.62±1.10 | 3.29±10.04 | 6.0±10.72 | 1.17±1.47 |
T1 | 0.94±3.84 | 2.11±6.03 | 0.91±1.70¶ | 4.17±5.49 |
Obstructive apnoeas n | | | | |
T0 | 0.65±1.62 | 4.89±9.37 | 37.13±64.40 | 35.33±76.35 |
T1 | 2.04±5.45 | 3.47±5.85 | 1.00±2.31¶ | 1.17±2.40 |
Mixed apnoeas n | | | | |
T0 | 0.02±0.14 | 0.42±1.10 | 3.17±10.08 | 0.83±1.33 |
T1 | 0.62±3.64 | 0.64±1.58 | 0.09±0.42 | 0.0±0.0 |
Hypopnoeas n | | | | |
T0 | 2.96±3.51 | 16.39±19.32 | 53.74±70.76 | 120.67±107.22 |
T1 | 5.00±8.61 | 9.44±14.07¶ | 8.70±16.39¶ | 10.83±25.56 |
Flow-limited events n | | | | |
T0 | 5.60±4.70 | 26.53±19.56 | 30.17±37.99 | 14.83±15.54 |
T1 | 6.17±11.28 | 12.75±16.50¶ | 13.00±15.68¶ | 0.50±0.84¶ |
RDI events·h−1 TST | | | | |
T0 | 1.48±0.83 | 8.57±8.35 | 18.92±20.15 | 30.10±18.33 |
T1 | 2.24±2.93 | 4.70±4.91# | 3.60±3.50# | 2.80±5.83¶ |
REMS RDI events·h−1 TST | | | | |
T0 | 1.74±2.12 | 6.07±6.11 | 21.14±30.85 | 36.99±33.66 |
T1 | 1.57±2.80 | 3.69±4.31¶ | 6.42±12.29¶ | 1.92±1.27¶ |
NREMS RDI events·h−1 TST | | | | |
T0 | 1.17±1.09 | 6.03±5.68 | 16.15±20.30 | 27.67±17.40 |
T1 | 2.02±3.14 | 4.14±5.10¶ | 3.10±3.54¶ | 1.53±3.26¶ |
ORDI events·h−1 TST | | | | |
T0 | 1.34±0.85 | 7.98±4.91 | 17.88±19.06 | 29.29±18.28 |
T1 | 2.06±2.83 | 4.34±4.48# | 3.33±3.60# | 2.10±4.92¶ |
Central AHI events·h−1 TST | | | | |
T0 | 0.09±0.18 | 0.59±2.03 | 0.85±1.55 | 0.19±0.17 |
T1 | 0.15±0.64 | 0.35±0.90 | 0.12±0.22¶ | 0.69±0.94 |
OAHI events·h−1 TST | | | | |
T0 | 0.57±0.60 | 3.57±3.90 | 13.54±19.77 | 27.36±18.89 |
T1 | 1.16±1.82¶ | 2.25±2.99¶ | 1.38±2.38# | 2.05±4.77¶,+ |
Apnoea index events·h−1 TST | | | | |
T0 | 0.20±0.32 | 1.40±2.82 | 6.74±12.64 | 6.34±13.25 |
T1 | 0.55±1.32 | 1.02±1.64 | 0.28±0.43¶ | 0.88±1.34 |
Hypopnoea index events·h−1 TST | | | | |
T0 | 0.47±0.57 | 2.70±3.01 | 7.62±10.16 | 21.19±18.54 |
T1 | 0.76±1.37 | 1.58±2.60 | 1.22±2.25¶ | 1.86±4.36¶,+ |
Flow limited index events·h−1 TST | | | | |
T0 | 0.86±0.72 | 4.36±3.26 | 4.08±4.85 | 2.62±2.29 |
T1 | 0.93±1.68 | 2.07±2.81¶ | 1.89±2.11¶ | 0.07±0.14¶,+ |
Baseline SaO2 | | | | |
T0 | 98.27±1.43 | 97.60±1.83 | 98.48±1.24 | 99.17±1.16 |
T1 | 97.96±1.01 | 97.54±1.36 | 98.35±0.94 | 99.17±0.41 |
Mean SaO2 | | | | |
T0 | 96.50±1.49 | 96.08±1.64 | 95.91±2.64 | 96.17±1.16 |
T1 | 96.31±1.18 | 96.17±1.36 | 96.57±1.30 | 97.00±1.09 |
Nadir SaO2 | | | | |
T0 | 91.29±3.63 | 90.44±3.02 | 86.86±10.96 | 87.50±3.61 |
T1 | 91.06±3.10 | 90.31±3.95 | 90.27±3.73¶ | 93.00±1.55¶,+ |
T90% | | | | |
T0 | 1.31±5.13 | 3.27±14.70 | 2.54±10.25 | 0.28±0.36 |
T1 | 0.23±1.28 | 0.28±0.68 | 0.09±0.34 | 0.00±0.00 |
ODI | | | | |
T0 | 0.18±0.50 | 1.95±4.00 | 6.84±21.60 | 19.88±19.25 |
T1 | 0.24±0.56 | 1.57±2.67 | 0.94±2.38 | 0.42±0.57¶,+ |
Peak PETCO2 mmHg | | | | |
T0 | 47.10±4.65 | 47.76±5.55 | 47.95±5.44 | 46.33±4.03 |
T1 | 47.15±5.11 | 44.26±5.45 | 47.84±5.38 | 50.00±3.69 |
PETCO2 >50 mmHg %TST | | | | |
T0 | 2.79±6.62 | 4.30±11.34 | 10.01±22.11 | 1.82±4.45 |
T1 | 7.90±14.03¶ | 3.06±7.82 | 3.80±9.11 | 3.32±7.98 |
Mean heart rate beats·min−1 | | | | |
T0 | 77.44±10.09 | 80.89±16.06 | 85.76±11.92 | 83.50±8.26 |
T1 | 75.10±10.45¶ | 77.03±17.58¶ | 76.05±12.37# | 76.67±8.82¶,+ |
Sleep measures | | | | |
Sleep efficiency % | | | | |
T0 | 79.99±10.02 | 78.89±10.61 | 84.75±8.27 | 69.76±21.61 |
T1 | 81.54±9.89 | 79.74±16.55 | 83.11±11.36 | 81.86±13.69 |
NREMS latency mins | | | | |
T0 | 34.80±24.07 | 31.83±23.27 | 24.13±19.58 | 46.42±26.29 |
T1 | 33.04±29.40 | 31.77±33.45 | 35.59±36.35 | 15.75±22.63 |
REMS latency mins | | | | |
T0 | 123.72±54.33 | 123.31±79.70 | 127.98±75.81 | 222.30±74.64 |
T1 | 137.30±68.28 | 150.39±80.90 | 126.13±48.35 | 158.00±60.68 |
Awake %TST | | | | |
T0 | 22.63±13.68 | 22.76±18.82 | 15.52±11.16 | 23.00±23.56 |
T1 | 24.48±16.38 | 19.60±20.56 | 18.10±15.17 | 14.70±10.06 |
N1 % | | | | |
T0 | 11.82±8.00 | 11.29±10.70 | 12.02±7.80 | 14.25±5.90 |
T1 | 12.58±8.13 | 9.82±8.97 | 11.29±6.85 | 9.19±5.80 |
N2 % | | | | |
T0 | 43.04±8.16 | 43.03±9.93 | 42.50±12.30 | 40.41±11.04 |
T1 | 42.67±8.75 | 41.79±12.77 | 43.32±11.61 | 46.31±8.23 |
N3 % | | | | |
T0 | 25.95±10.85 | 29.21±12.17 | 27.70±23.85 | 36.02±16.13 |
T1 | 24.91±9.78¶ | 31.20±13.69¶ | 26.68±20.57 | 33.91±12.23 |
REMS % | | | | |
T0 | 19.19±6.24 | 16.47±5.93 | 18.25±6.57 | 9.30±4.99 |
T1 | 19.85±5.14 | 17.18±6.11 | 20.71±7.33 | 12.97±3.87 |
Arousal index | | | | |
T0 | 9.44±7.50 | 16.85±10.99 | 13.73±19.24 | 25.72±14.67 |
T1 | 10.30±7.63 | 12.64±6.74¶ | 12.83±7.07 | 9.72±4.39¶,+ |
PLM index | | | | |
T0 | 0.22±0.87 | 1.45±3.22 | 1.00±3.33 | 7.10±8.07 |
T1 | 0.15±0.64 | 1.31±3.82 | 1.24±4.46 | 1.00±1.41 |