Extract
Patients with chronic obstructive pulmonary disease (COPD) often suffer other concomitant diseases that negatively impact their prognosis and health status [1]. However, it is unclear if they are causally related to COPD or result from shared risk factors, such as ageing, smoking and/or inactivity [2]. Likewise, the precise underlying molecular mechanisms are also unclear [3], hence limiting targeted therapeutic interventions. The use of network analysis can help to elucidate this conundrum [4].
Abstract
Network analysis of comorbidities in COPD patients provides new insights into the pathobiology of disease http://ow.ly/Ph44T
Footnotes
Conflict of interest: Disclosures can be found alongside the online version of this article at erj.ersjournals.com
- Received April 7, 2015.
- Accepted April 20, 2015.
- Copyright ©ERS 2015