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Table of Contents

01 May 2015; volume 45, issue 5

Electronic Resources

  • You have accessRestricted access
    European Respiratory Journal 45 (5) E53; Published 30 April 2015
    • ERJ Podcast

Editorials

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    Barriers to new drug development in respiratory disease
    Peter J. Barnes, Sergio Bonini, Werner Seeger, Maria G. Belvisi, Brian Ward, Anthony Holmes
    European Respiratory Journal 45 (5) 1197-1207; DOI: 10.1183/09031936.00007915 Published 30 April 2015
    • Disclosures
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    Combination therapy in idiopathic pulmonary fibrosis: the way ahead will be hard
    Athol Wells
    European Respiratory Journal 45 (5) 1208-1210; DOI: 10.1183/09031936.00043915 Published 30 April 2015
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    What is new about Rio?
    Rogerio Souza, Steven M. Kawut
    European Respiratory Journal 45 (5) 1211-1213; DOI: 10.1183/09031936.00032715 Published 30 April 2015
    • Disclosures
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    Lung cancer in never-smokers
    David Planchard, Benjamin Besse
    European Respiratory Journal 45 (5) 1214-1217; DOI: 10.1183/09031936.00046915 Published 30 April 2015
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    Where do we go from here? Clinical drug development in idiopathic pulmonary fibrosis
    Harold R. Collard
    European Respiratory Journal 45 (5) 1218-1220; DOI: 10.1183/09031936.00237114 Published 30 April 2015
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    Development of a syllabus for postgraduate respiratory physiotherapy education: the Respiratory Physiotherapy HERMES project
    Thierry Troosters, Fabio Pitta, Beatrice Oberwaldner, Agnieszka Lewko, Deniz Inal-Ince, Kathleen Grant, Rik Gosselink, Chris Burtin, Margareta Emtner, Enrico Clini, Michelle Chatwin, Sharon Mitchell
    European Respiratory Journal 45 (5) 1221-1223; DOI: 10.1183/09031936.00037215 Published 30 April 2015
  • European Lung Corner

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      A free lung health check for the European Parliament: Healthy Lungs for Life
      Marine Faure
      European Respiratory Journal 45 (5) 1224-1225; DOI: 10.1183/09031936.00022615 Published 30 April 2015

From the Museum

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    From the Museum: the Art of Thinking. Summary 5-8: Sensing In.
    Tom Kotsimbos
    European Respiratory Journal 45 (5) 1226-1227; DOI: 10.1183/09031936.00450515 Published 30 April 2015

Original Articles

  • Epidemiology

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      Indoor air quality, ventilation and respiratory health in elderly residents living in nursing homes in Europe
      Malek Bentayeb, Dan Norback, Micha Bednarek, Alfred Bernard, Guihong Cai, Sonia Cerrai, Konstantinos Kostas Eleftheriou, Christina Gratziou, Gitte Juel Holst, François Lavaud, Jacek Nasilowski, Piersante Sestini, Giuseppe Sarno, Torben Sigsgaard, Gunilla Wieslander, Jan Zielinski, Giovanni Viegi, Isabella Annesi-Maesano on behalf of the GERIE Study
      European Respiratory Journal 45 (5) 1228-1238; DOI: 10.1183/09031936.00082414 Published 30 April 2015
  • COPD

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      Global and regional trends in COPD mortality, 1990–2010
      Peter G.J. Burney, Jaymini Patel, Roger Newson, Cosetta Minelli, Mohsen Naghavi
      European Respiratory Journal 45 (5) 1239-1247; DOI: 10.1183/09031936.00142414 Published 30 April 2015
      • ERJ Podcast
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      Obesity as a susceptibility factor to indoor particulate matter health effects in COPD
      Meredith C. McCormack, Andrew J. Belli, Deepak A. Kaji, Elizabeth C. Matsui, Emily P. Brigham, Roger D. Peng, Cortlandt Sellers, D'Ann L. Williams, Gregory B. Diette, Patrick N. Breysse, Nadia N. Hansel
      European Respiratory Journal 45 (5) 1248-1257; DOI: 10.1183/09031936.00081414 Published 30 April 2015
      • Disclosures
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      Imprinting of the COPD airway epithelium for dedifferentiation and mesenchymal transition
      Sophie T. Gohy, Cloé Hupin, Chantal Fregimilicka, Bruno R. Detry, Caroline Bouzin, Héloïse Gaide Chevronay, Marylène Lecocq, Birgit Weynand, Maha Z. Ladjemi, Christophe E. Pierreux, Philippe Birembaut, Myriam Polette, Charles Pilette
      European Respiratory Journal 45 (5) 1258-1272; DOI: 10.1183/09031936.00135814 Published 30 April 2015
  • Asthma

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      Nebulised budesonide using a novel device in patients with oral steroid-dependent asthma
      Claus Vogelmeier, Peter Kardos, Thomas Hofmann, Sebastian Canisius, Gerhard Scheuch, Bernhard Muellinger, Karlheinz Nocker, Guenter Menz, Klaus F. Rabe
      European Respiratory Journal 45 (5) 1273-1282; DOI: 10.1183/09031936.00152014 Published 30 April 2015
      • Disclosures
  • Lung function

    • Open Access
      Use of forced vital capacity and forced expiratory volume in 1 second quality criteria for determining a valid test
      John L. Hankinson, Bill Eschenbacher, Mary Townsend, Janet Stocks, Philip H. Quanjer
      European Respiratory Journal 45 (5) 1283-1292; DOI: 10.1183/09031936.00116814 Published 30 April 2015
      • Supplementary material
      • Disclosures
  • Pulmonary vascular diseases

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      Riociguat for the treatment of chronic thromboembolic pulmonary hypertension: a long-term extension study (CHEST-2)
      Gérald Simonneau, Andrea M. D’Armini, Hossein-Ardeschir Ghofrani, Friedrich Grimminger, Marius M. Hoeper, Pavel Jansa, Nick H. Kim, Chen Wang, Martin R. Wilkins, Arno Fritsch, Neil Davie, Pablo Colorado, Eckhard Mayer
      European Respiratory Journal 45 (5) 1293-1302; DOI: 10.1183/09031936.00087114 Published 30 April 2015
      • Disclosures
      • Supplementary material
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      Riociguat for the treatment of pulmonary arterial hypertension: a long-term extension study (PATENT-2)
      Lewis J. Rubin, Nazzareno Galiè, Friedrich Grimminger, Ekkehard Grünig, Marc Humbert, Zhi-Cheng Jing, Anne Keogh, David Langleben, Arno Fritsch, Flavia Menezes, Neil Davie, Hossein-Ardeschir Ghofrani
      European Respiratory Journal 45 (5) 1303-1313; DOI: 10.1183/09031936.00090614 Published 30 April 2015
      • Disclosures
      • Supplementary material
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      PATENT PLUS: a blinded, randomised and extension study of riociguat plus sildenafil in pulmonary arterial hypertension
      Nazzareno Galiè, Katharina Müller, Andrea-Viviana Scalise, Ekkehard Grünig
      European Respiratory Journal 45 (5) 1314-1322; DOI: 10.1183/09031936.00105914 Published 30 April 2015
      • Supplementary material
      • Disclosures
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      Age-adjusted high-sensitivity troponin T cut-off value for risk stratification of pulmonary embolism
      Anja Kaeberich, Valerie Seeber, David Jiménez, Maciej Kostrubiec, Claudia Dellas, Gerd Hasenfuß, Evangelos Giannitsis, Piotr Pruszczyk, Stavros Konstantinides, Mareike Lankeit
      European Respiratory Journal 45 (5) 1323-1331; DOI: 10.1183/09031936.00174514 Published 30 April 2015
      • Disclosures
      • Supplementary material
  • Sleep

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      Obstructive respiratory events and premature atrial contractions after cardioversion
      Dominik Linz, Mathias Hohl, Christian Ukena, Felix Mahfoud, Klaus Wirth, Hans-Ruprecht Neuberger, Michael Böhm
      European Respiratory Journal 45 (5) 1332-1340; DOI: 10.1183/09031936.00175714 Published 30 April 2015
  • Critical care

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      Complicated grief after death of a relative in the intensive care unit
      Nancy Kentish-Barnes, Marine Chaize, Valérie Seegers, Stéphane Legriel, Alain Cariou, Samir Jaber, Jean-Yves Lefrant, Bernard Floccard, Anne Renault, Isabelle Vinatier, Armelle Mathonnet, Danielle Reuter, Olivier Guisset, Zoé Cohen-Solal, Christophe Cracco, Amélie Seguin, Jacques Durand-Gasselin, Béatrice Éon, Marina Thirion, Jean-Philippe Rigaud, Bénédicte Philippon-Jouve, Laurent Argaud, Renaud Chouquer, Mélanie Adda, Céline Dedrie, Hugues Georges, Eddy Lebas, Nathalie Rolin, Pierre-Edouard Bollaert, Lucien Lecuyer, Gérard Viquesnel, Marc Léone, Ludivine Chalumeau-Lemoine, Maïté Garrouste, Benoit Schlemmer, Sylvie Chevret, Bruno Falissard, Élie Azoulay
      European Respiratory Journal 45 (5) 1341-1352; DOI: 10.1183/09031936.00160014 Published 30 April 2015
  • Respiratory infections

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      Bacteraemia and antibiotic-resistant pathogens in community acquired pneumonia: risk and prognosis
      Antoni Torres, Catia Cillóniz, Miquel Ferrer, Albert Gabarrús, Eva Polverino, Santiago Villegas, Francesc Marco, Josep Mensa, Rosario Menéndez, Michael Niederman
      European Respiratory Journal 45 (5) 1353-1363; DOI: 10.1183/09031936.00152514 Published 30 April 2015
      • Supplementary material
  • Tuberculosis

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      Incidence of occupational latent tuberculosis infection in South African healthcare workers
      Shahieda Adams, Rodney Ehrlich, Roslynn Baatjies, Richard N. van Zyl-Smit, Qonita Said-Hartley, Rodney Dawson, Keertan Dheda
      European Respiratory Journal 45 (5) 1364-1373; DOI: 10.1183/09031936.00138414 Published 30 April 2015
      • Supplementary material
      • Disclosures
  • Interstitial lung diseases

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      Unified baseline and longitudinal mortality prediction in idiopathic pulmonary fibrosis
      Brett Ley, Williamson Z. Bradford, Derek Weycker, Eric Vittinghoff, Roland M. du Bois, Harold R. Collard
      European Respiratory Journal 45 (5) 1374-1381; DOI: 10.1183/09031936.00146314 Published 30 April 2015
      • Disclosures
      • Supplementary material
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      Safety and pharmacokinetics of nintedanib and pirfenidone in idiopathic pulmonary fibrosis
      Takashi Ogura, Hiroyuki Taniguchi, Arata Azuma, Yoshikazu Inoue, Yasuhiro Kondoh, Yoshinori Hasegawa, Masashi Bando, Shinji Abe, Yoshiro Mochizuki, Kingo Chida, Matthias Klüglich, Tsuyoshi Fujimoto, Kotaro Okazaki, Yusuke Tadayasu, Wataru Sakamoto, Yukihiko Sugiyama
      European Respiratory Journal 45 (5) 1382-1392; DOI: 10.1183/09031936.00198013 Published 30 April 2015
      • Disclosures
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      Oral immunotherapy with type V collagen in idiopathic pulmonary fibrosis
      David S. Wilkes, Terrence Chew, Kevin R. Flaherty, Sarah Frye, Kevin F. Gibson, Naftali Kaminski, Michael J. Klemsz, Wade Lange, Imre Noth, Katia Rothhaar
      European Respiratory Journal 45 (5) 1393-1402; DOI: 10.1183/09031936.00105314 Published 30 April 2015
      • Disclosures
  • Lung cancer

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      BioCAST/IFCT-1002: epidemiological and molecular features of lung cancer in never-smokers
      Sébastien Couraud, Pierre-Jean Souquet, Christophe Paris, Pascal Dô, Hélène Doubre, Eric Pichon, Adrien Dixmier, Isabelle Monnet, Bénédicte Etienne-Mastroianni, Michel Vincent, Jean Trédaniel, Marielle Perrichon, Pascal Foucher, Bruno Coudert, Denis Moro-Sibilot, Eric Dansin, Stéphanie Labonne, Pascale Missy, Franck Morin, Hélène Blanché, Gérard Zalcman on behalf of The French Cooperative Intergroup IFCT
      European Respiratory Journal 45 (5) 1403-1414; DOI: 10.1183/09031936.00097214 Published 30 April 2015
      • Disclosures
      • Supplementary material
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      No impact of passive smoke on the somatic profile of lung cancers in never-smokers
      Sébastien Couraud, Didier Debieuvre, Lionel Moreau, Patrick Dumont, Jacques Margery, Elisabeth Quoix, Bernard Duvert, Laurent Cellerin, Nathalie Baize, Bruno Taviot, Marie Coudurier, Jacques Cadranel, Pascale Missy, Franck Morin, Jean-François Mornex, Gérard Zalcman, Pierre-Jean Souquet onbehalf of the BioCAST/IFCT-1002 study investigators
      European Respiratory Journal 45 (5) 1415-1425; DOI: 10.1183/09031936.00097314 Published 30 April 2015
      • Disclosures
      • Supplementary material

Review

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    The role of tyrosine kinases in the pathogenesis of idiopathic pulmonary fibrosis
    Friedrich Grimminger, Andreas Günther, Carlo Vancheri
    European Respiratory Journal 45 (5) 1426-1433; DOI: 10.1183/09031936.00149614 Published 30 April 2015
    • Disclosures
  • Open Access
    Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis
    Lutz Wollin, Eva Wex, Alexander Pautsch, Gisela Schnapp, Katrin E. Hostettler, Susanne Stowasser, Martin Kolb
    European Respiratory Journal 45 (5) 1434-1445; DOI: 10.1183/09031936.00174914 Published 30 April 2015
    • Disclosures
    • Supplementary material

State of the Art

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    Management of bronchiectasis in adults
    James D. Chalmers, Stefano Aliberti, Francesco Blasi
    European Respiratory Journal 45 (5) 1446-1462; DOI: 10.1183/09031936.00119114 Published 30 April 2015
    • Disclosures

Back to Basics

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    Influenza virus-induced lung injury: pathogenesis and implications for treatment
    Susanne Herold, Christin Becker, Karen M. Ridge, G.R. Scott Budinger
    European Respiratory Journal 45 (5) 1463-1478; DOI: 10.1183/09031936.00186214 Published 30 April 2015

Agora

  • Research letters

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      The global epidemiology of chronic cough in adults: a systematic review and meta-analysis
      Woo-Jung Song, Yoon-Seok Chang, Shoaib Faruqi, Ju-Young Kim, Min-Gyu Kang, Sujeong Kim, Eun-Jung Jo, Min-Hye Kim, Jana Plevkova, Heung-Woo Park, Sang-Heon Cho, Alyn H. Morice
      European Respiratory Journal 45 (5) 1479-1481; DOI: 10.1183/09031936.00218714 Published 30 April 2015
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      Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patients
      Simon D. Pouwels, Martijn C. Nawijn, Erik Bathoorn, Annelies Riezebos-Brilman, Antoon J.M. van Oosterhout, Huib A.M. Kerstjens, Irene H. Heijink
      European Respiratory Journal 45 (5) 1482-1485; DOI: 10.1183/09031936.00158414 Published 30 April 2015
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      Increased expression of granzymes A and B in fatal asthma
      Raquel Annoni, Luiz Fernando F. Silva, Yvonne Nussbaumer-Ochsner, Annemarie van Schadewijk, Thais Mauad, Pieter S. Hiemstra, Klaus F. Rabe
      European Respiratory Journal 45 (5) 1485-1488; DOI: 10.1183/09031936.00213814 Published 30 April 2015
      • Disclosures
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      Defining the appropriate waiting time between multiple-breath nitrogen washout measurements
      Elizabeth R. Salamon, Kevin R. Gain, Graham L. Hall
      European Respiratory Journal 45 (5) 1489-1491; DOI: 10.1183/09031936.00198414 Published 30 April 2015
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      Dual gas techniques for peripheral airway function: diffusing the issues
      Sylvia Verbanck, Manuel Paiva
      European Respiratory Journal 45 (5) 1491-1494; DOI: 10.1183/09031936.00207514 Published 30 April 2015
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      Inspiratory muscle function, dynamic hyperinflation and exertional dyspnoea in pulmonary arterial hypertension
      Pierantonio Laveneziana, Marc Humbert, Laurent Godinas, Barbara Joureau, Roxane Malrin, Christian Straus, Xavier Jaïs, Olivier Sitbon, Gérald Simonneau, Thomas Similowski, Gilles Garcia
      European Respiratory Journal 45 (5) 1495-1498; DOI: 10.1183/09031936.00153214 Published 30 April 2015
    • Open Access
      Long-term mortality assessment of multidrug-resistant tuberculosis patients treated with delamanid
      Charles D. Wells, Rajesh Gupta, Norbert Hittel, Lawrence J. Geiter
      European Respiratory Journal 45 (5) 1498-1501; DOI: 10.1183/09031936.00176314 Published 30 April 2015
      • Disclosures
    • You have accessRestricted access
      Is 1-year follow-up adequate for adult tuberculosis contacts?
      Jia-Yih Feng, San-Chi Chen, Ming-Che Lee, Wen-Chien Fan, Wei-Juin Su, Yu-Wen Hu, Chiu-Mei Yeh, Tzeng-Ji Chen, Chia-Jen Liu
      European Respiratory Journal 45 (5) 1501-1504; DOI: 10.1183/09031936.00142114 Published 30 April 2015
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      Suboptimal specificity of Xpert MTB/RIF among treatment-experienced patients
      John Z. Metcalfe, Salome Makumbirofa, Beauty Makamure, Reggie Mutetwa, Renée A. Peñaloza, Charles Sandy, Wilbert Bara, Stanley Mungofa, Philip C. Hopewell, Peter Mason
      European Respiratory Journal 45 (5) 1504-1506; DOI: 10.1183/09031936.00214114 Published 30 April 2015
  • Correspondence

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      Cough hypersensitivity syndrome: clinical measurement is the key to progress
      Richard D. Turner, Graham H. Bothamley
      European Respiratory Journal 45 (5) 1507-1508; DOI: 10.1183/09031936.00212714 Published 30 April 2015
    • You have accessRestricted access
      Cough hypersensitivity syndrome: clinical measurement is the key to progress
      Alyn H. Morice, Eva Millqvist, Maria G. Belvisi, Kristina Bieksiene, Surinder S. Birring, Kian Fan Chung, Roberto W. Dal Negro, Peter Dicpinigaitis, Ahmad Kantar, Lorcan P. McGarvey, Adalberto Pacheco, Raimundas Sakalauskas, Jaclyn A. Smith
      European Respiratory Journal 45 (5) 1509-1510; DOI: 10.1183/09031936.00014215 Published 30 April 2015
      • Disclosures
    • You have accessRestricted access
      Screening for latent tuberculosis before tumour necrosis factor antagonist therapy
      Richard J. Hewitt, Aran Singanayagam, Saranya Sridhar, Melissa Wickremasinghe, Onn Min Kon
      European Respiratory Journal 45 (5) 1510-1512; DOI: 10.1183/09031936.00194314 Published 30 April 2015
      • Disclosures
    • You have accessRestricted access
      Screening for latent tuberculosis before tumour necrosis factor antagonist therapy
      Michael R. Loebinger, Anton Pozniak
      European Respiratory Journal 45 (5) 1512-1513; DOI: 10.1183/09031936.00020315 Published 30 April 2015
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      Are C-reactive protein levels associated with bacteria in COPD exacerbations?
      Marc Miravitlles, Carl Llor
      European Respiratory Journal 45 (5) 1514-1515; DOI: 10.1183/09031936.00005415 Published 30 April 2015
    • You have accessRestricted access
      Are C-reactive protein levels associated with bacteria in COPD exacerbations?
      Tristan W. Clark
      European Respiratory Journal 45 (5) 1515-1516; DOI: 10.1183/09031936.00020015 Published 30 April 2015

Erratum

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    Erratum
    European Respiratory Journal 45 (5) 1517; DOI: 10.1183/09031936.50005914 Published 30 April 2015
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European Respiratory Journal: 45 (5)
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