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Clinical significance of C reactive protein and MASTORA score in pulmonary embolism

Jolita Rackauskiene, Vaida Gedvilaite, Mindaugas Mataciunas, Mazvile Abrutyte, Olga Kusner, Edvardas Danila
European Respiratory Journal 2014 44: P3659; DOI:
Jolita Rackauskiene
1Centre of Pulmonology and Allergology, Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania
6Faculty of Medicine, Vilnius University, Vilnius, Lithuania
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Vaida Gedvilaite
1Centre of Pulmonology and Allergology, Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania
6Faculty of Medicine, Vilnius University, Vilnius, Lithuania
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Mindaugas Mataciunas
2Centre of Radiology and Nuclear Medicine, Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania
4Department of Radiology, Nuclear Medicine and Physics of Medicine, Vilnius University, Vilnius, Lithuania
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Mazvile Abrutyte
6Faculty of Medicine, Vilnius University, Vilnius, Lithuania
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Olga Kusner
5The Pulmonology and Allergology Department, Republic Klaipeda Hospital, Klaipeda, Lithuania
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Edvardas Danila
1Centre of Pulmonology and Allergology, Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania
3Clinic of Infectious and Chest Diseases, Dermatovenereology and Allergology, Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania
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Abstract

Study aim: To evaluate clinical significance of C reactive protein (CRP) and MASTORA score in acute pulmonary embolism (PE).

Materials and methods: 125 consecutive patients with newly diagnosed acute PE were prospectively examined. PE was confirmed by the chest CT angiography. D-dimer, CRP level tests, echocardiography and venous ultrasonography of the legs were performed. Risk factors were also explored. PE scope was evaluated using the MASTORA score.

Results: D-dimer level <500 μg/l was seen in 4.2% cases. The probability of haemoptysis was significantly (p=0.001) higher when the pressure in the pulmonary artery was increased. Elevated CRP was found in the majority of the cases (78.4 %), but there were no associations with fever or the findings of opacities or consolidation in the chest CT scans. The higher D-dimer level significantly correlated with the overload of the right chambers of the heart (p=0.03).

The higher MASTORA score had a strong correlation with higher D-dimer level (r=0.362, p<0.0001), right heart chambers overload (p=0.006) and pulmonary infiltration (p=0.007).

PE caused the death of two (1.6%) patients.

Conclusions: D-dimer level<500 μg/l does not exclude PE, even a massive one. Haemoptysis in PE is associated with increased pressure in the pulmonary artery. The clinical significance of the CRP test and MASTORA score value is low in most acute PE cases.

  • Embolism
  • Imaging
  • © 2014 ERS
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Clinical significance of C reactive protein and MASTORA score in pulmonary embolism
Jolita Rackauskiene, Vaida Gedvilaite, Mindaugas Mataciunas, Mazvile Abrutyte, Olga Kusner, Edvardas Danila
European Respiratory Journal Sep 2014, 44 (Suppl 58) P3659;

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Clinical significance of C reactive protein and MASTORA score in pulmonary embolism
Jolita Rackauskiene, Vaida Gedvilaite, Mindaugas Mataciunas, Mazvile Abrutyte, Olga Kusner, Edvardas Danila
European Respiratory Journal Sep 2014, 44 (Suppl 58) P3659;
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