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Primary lung cancer treated using radiofrequency ablation: Two year outcome data

Julia Beeson, Vladimir Anikin, Sundeep Kaul, Dimitrios Kyparissopoulos, Paras Dalal
European Respiratory Journal 2014 44: P2719; DOI:
Julia Beeson
1Departrment of Thoracic Surgery and Radiology, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom
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Vladimir Anikin
1Departrment of Thoracic Surgery and Radiology, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom
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Sundeep Kaul
1Departrment of Thoracic Surgery and Radiology, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom
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Dimitrios Kyparissopoulos
1Departrment of Thoracic Surgery and Radiology, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom
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Paras Dalal
1Departrment of Thoracic Surgery and Radiology, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom
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Abstract

Purpose: Percutaneous image guided radiofrequency ablation (RFA) is increasingly used as an alternative treatment option for patients with inoperable primary lung cancer (NSCLC) but there are little published outcome data. We report safety & efficacy of RFA in patients with NSCLC (stages 1-4) at 1 & 2 years.

Methods and Materials: Under general anaesthesia 38 patients, underwent RFA of 50 pulmonary tumours. Survival were evaluated prospectively at 3, 6, 9,12 & 24 months whilst complications was assessed 1 month post procedure.

Results: There were no cases of procedure related mortality. Complications included pneumothorax requiring intercostal drain (ICD) insertion (n=20, 53%), small pneumothorax not requiring ICD (n=3, 8%) and pleural effusion (n=2, 5%). One year overall survival and cancer specific (C/S) for tumours classified as Stage 1 (n=20) were 100% and 100% respectively. Stage 2 (n=7) 85% & 100% respectively and stage 4 (n=11) 64% & 73% respectively. Two year survivals (overall & C/S) for Stage 1 were 85% & 95%, in Stage 2 patients 43% & 86% and those at Stage 4 45% & 64% respectively.

Conclusion: RFA is a safe, effective and well-tolerated treatment option in patients with inoperable lung cancer. Our study also shows that ablation therapy may be useful in higher stage tumours.

  • Lung cancer / Oncology
  • Imaging
  • © 2014 ERS
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Primary lung cancer treated using radiofrequency ablation: Two year outcome data
Julia Beeson, Vladimir Anikin, Sundeep Kaul, Dimitrios Kyparissopoulos, Paras Dalal
European Respiratory Journal Sep 2014, 44 (Suppl 58) P2719;

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Primary lung cancer treated using radiofrequency ablation: Two year outcome data
Julia Beeson, Vladimir Anikin, Sundeep Kaul, Dimitrios Kyparissopoulos, Paras Dalal
European Respiratory Journal Sep 2014, 44 (Suppl 58) P2719;
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