Abstract
Background: Some papers showed the possibility of EBUS-TBNA in the verification of isolated mediastinal lymphadenopathy (Ye T., 2011) Diagnostic accuracy of this method is highly variable in different authors. The relationship of number of lymph node passes and adequacy EBUS-TBNA specimens is significantly (Yarmus L.,2013). The role of EBUS-TBNA with rapid on-site evaluation (ROSE) is unknown for verification of isolated mediastinal lymphadenopathy (IML).
Aim: To determine the role of ROSE in the adequacy of EBUS-TBNA specimens.
Methods: Prospective clinical trial of 25 consecutive patients with IML during 2013. All patients underwent EBUS-TBNA of mediastinal lymph nodes. VATS procedure performed as a gold standard. All specimens underwent morphological, microbiological analysis and PCR. Before procedure patients were separated into 2 groups. ROSE was made in group 1 (13 patients/52%). ROSE was not done in group 2 (12 patients/48%).
Results: EBUS-TBNA specimens were accepted pathologically adequate from 13/100% patients in 1 group, from 6/50% patients in 2 group (p<0.05).
Conclusion: Performance ROSE is more preferable to increase adequacy of EBUS-TBNA specimens.
- © 2014 ERS
