Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions

An overview of thrombolytic treatment for pulmonary embolism: A single center experience

Hadice Selimoglu Sen, Ozlem Abakay, Cengizhan Sezgi, Sureyya Yilmaz, Mahsuk Taylan, Halide Kaya, Abdullah Cetin Tanrikulu, Abdurrahman Abakay
European Respiratory Journal 2014 44: P2393; DOI:
Hadice Selimoglu Sen
1Pulmonology, Dicle University School of Medicine, Diyarbakir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ozlem Abakay
1Pulmonology, Dicle University School of Medicine, Diyarbakir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Cengizhan Sezgi
1Pulmonology, Dicle University School of Medicine, Diyarbakir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sureyya Yilmaz
1Pulmonology, Dicle University School of Medicine, Diyarbakir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mahsuk Taylan
1Pulmonology, Dicle University School of Medicine, Diyarbakir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Halide Kaya
1Pulmonology, Dicle University School of Medicine, Diyarbakir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Abdullah Cetin Tanrikulu
1Pulmonology, Dicle University School of Medicine, Diyarbakir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Abdurrahman Abakay
1Pulmonology, Dicle University School of Medicine, Diyarbakir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
Loading

Abstract

Introduction: A massive pulmonary embolism (MPE) has a poor prognosis and high mortality. Thrombolytic therapy is preferred in patients with life-threatening symptoms such as hypotension, cardiogenic shock, and right ventricular failure due to the risk of severe bleeding.

Materials and Methods: This is a retrospective analysis of patients who were hospitalized with the diagnosis of pulmonary embolism (PE) and given thrombolytic therapy in the chest diseases clinic of a tertiary university hospital between January 2008 and November 2013.

Results: The subjects' mean age was 59.54 ± 13.76 years. Fourteen of 39 patients who were treated with thrombolytic therapy were male (35.89%) and 25 (64.10%) were female. The symptoms experienced by the patients included dyspnea in 39 patients, chest pain in 35 patients, hemoptysis in 6 patients, syncope in 13 patients and cough in 10 patients. Risk factors were advanced age (> 60 years) in 19, immobilization in 19, malignancy in 3, major surgery in 11 patients. The in-hospital mortality analysis showed that 32 patients were discharged and 7 patients died. Four patients died from their pulmonary embolism and 3 patients died because of a major bleeding complication.

Conclusions: Pulmonary embolism is a disease that may lead to death within hours secondary to acute right heart failure. Early diagnosis and treatment can be life saving. Thrombolytic therapy has been shown to improve hemodynamic parameters in the early period post-PE. An increased risk of bleeding is one of the most important drawbacks of thrombolytic therapy. Nonetheless, it can be a life-saving therapy in properly selected patients.

  • Circulation
  • © 2014 ERS
Previous
Back to top
Vol 44 Issue Suppl 58 Table of Contents
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
An overview of thrombolytic treatment for pulmonary embolism: A single center experience
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
An overview of thrombolytic treatment for pulmonary embolism: A single center experience
Hadice Selimoglu Sen, Ozlem Abakay, Cengizhan Sezgi, Sureyya Yilmaz, Mahsuk Taylan, Halide Kaya, Abdullah Cetin Tanrikulu, Abdurrahman Abakay
European Respiratory Journal Sep 2014, 44 (Suppl 58) P2393;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
An overview of thrombolytic treatment for pulmonary embolism: A single center experience
Hadice Selimoglu Sen, Ozlem Abakay, Cengizhan Sezgi, Sureyya Yilmaz, Mahsuk Taylan, Halide Kaya, Abdullah Cetin Tanrikulu, Abdurrahman Abakay
European Respiratory Journal Sep 2014, 44 (Suppl 58) P2393;
del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo

Jump To

  • Article
  • Info & Metrics
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

  • Selective TSC1 deletion in smooth muscle activates mTOR signaling and induces pulmonary hypertension
  • Balancing TGFbeta/BMP in pulmonary arterial hypertension
  • Endothelial-derived MIF contributes to pulmonary endothelial cell proliferation in human pulmonary arterial hypertension
Show more 4.3 Pulmonary Circulation and Pulmonary Vascular Disease

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Reviewers
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Publication ethics and malpractice
  • Submit a manuscript

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2022 by the European Respiratory Society