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Local effect of airway clearance techniques in COPD patients

Kris Ides, Cedric Van Holsbeke, Glenn Leemans, Wim Vos, Jan De Backer, Rita Claes, Dirk Vissers, Wilfried De Backer
European Respiratory Journal 2014 44: P1275; DOI:
Kris Ides
1Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium
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Cedric Van Holsbeke
2Respiratory, Fluidda nv, Kontich, Belgium
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Glenn Leemans
1Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium
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Wim Vos
2Respiratory, Fluidda nv, Kontich, Belgium
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Jan De Backer
2Respiratory, Fluidda nv, Kontich, Belgium
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Rita Claes
3Respiratory Medicine, University Hospital Antwerp, Edegem, Belgium
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Dirk Vissers
1Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium
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Wilfried De Backer
1Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium
3Respiratory Medicine, University Hospital Antwerp, Edegem, Belgium
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Abstract

Rationale

A lot of comparative research has been conducted on the effects of airway clearance techniques. Lung function testing does not allow evaluating regional changes. Recent advances in imaging techniques do provide a new method for the evaluation of the airways and allow for the calculation of regional differences. Are the effects of two different airway clearance techniques (ACT) measurable with functional respiratory imaging (FRI)?

Methods

6 COPD patients were included and evaluated between the 3 and 5the day of hospital admission for an acute exacerbation. Two groups of 3 patients were treated for one week using IPV or autogenic drainage. Pulmonary function tests (PFT) and FRI were performed baseline and post treatment.

Results

In this small sample no significant differences in response were observed between both groups. For the total study group PFT showed a small significant change in vital capacity (+8%, p=0.03) and residual volume (-7%, p=0.03). FEV1 did not change significantly (+7%, p=0.09). FRI showed significant changes in airway volume (+31%, p<0.001) and resistance (iRaw, -43%, p<0.001), with large lobar heterogeneity (±90% for iRaw) within each patient .

Conclusions

This preliminary data suggests that FRI can be used to visualize local effects of ACT's in COPD patients. The clinical relevance of the changes detected using FRI will be subject of further research.

  • COPD - management
  • Rehabilitation
  • Physiotherapy care
  • © 2014 ERS
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Local effect of airway clearance techniques in COPD patients
Kris Ides, Cedric Van Holsbeke, Glenn Leemans, Wim Vos, Jan De Backer, Rita Claes, Dirk Vissers, Wilfried De Backer
European Respiratory Journal Sep 2014, 44 (Suppl 58) P1275;

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Local effect of airway clearance techniques in COPD patients
Kris Ides, Cedric Van Holsbeke, Glenn Leemans, Wim Vos, Jan De Backer, Rita Claes, Dirk Vissers, Wilfried De Backer
European Respiratory Journal Sep 2014, 44 (Suppl 58) P1275;
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