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Physiological and sensorial effects of surgical treatment for bronchiectasis

Camilla Carlini Vallilo, Andre Luis Pereira de Albuquerque, Ricardo Mingarini Terra, João Marcos Salge, Milena Mako Suesada, Marcia Cistina Augusto, Fabiane Polisel, Edilene de Morais, Paulo Manuel Pêgo-Fernendes
European Respiratory Journal 2014 44: 1921; DOI:
Camilla Carlini Vallilo
1Thoracic Surgery Division, Heart Institute (InCor) of Hospital das Clinicas, University of Sao Paulo Medical School, São Paulo, Brazil
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Andre Luis Pereira de Albuquerque
2Pulmonology Division, Heart Institute (InCor) of Hospital das Clinicas, University of Sao Paulo Medical School, São Paulo, Brazil
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Ricardo Mingarini Terra
1Thoracic Surgery Division, Heart Institute (InCor) of Hospital das Clinicas, University of Sao Paulo Medical School, São Paulo, Brazil
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João Marcos Salge
2Pulmonology Division, Heart Institute (InCor) of Hospital das Clinicas, University of Sao Paulo Medical School, São Paulo, Brazil
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Milena Mako Suesada
1Thoracic Surgery Division, Heart Institute (InCor) of Hospital das Clinicas, University of Sao Paulo Medical School, São Paulo, Brazil
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Marcia Cistina Augusto
1Thoracic Surgery Division, Heart Institute (InCor) of Hospital das Clinicas, University of Sao Paulo Medical School, São Paulo, Brazil
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Fabiane Polisel
2Pulmonology Division, Heart Institute (InCor) of Hospital das Clinicas, University of Sao Paulo Medical School, São Paulo, Brazil
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Edilene de Morais
2Pulmonology Division, Heart Institute (InCor) of Hospital das Clinicas, University of Sao Paulo Medical School, São Paulo, Brazil
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Paulo Manuel Pêgo-Fernendes
1Thoracic Surgery Division, Heart Institute (InCor) of Hospital das Clinicas, University of Sao Paulo Medical School, São Paulo, Brazil
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Abstract

Background: Bronchiectasis is a significant cause of morbidity and surgical treatment is commonly indicated. Objective: To evaluate the physiological and sensorial effects of surgery in patients with bronchiectasis who failed to medical treatment.

Methods: All patients with non-cystic fibrosis were submitted to thoracotomy. The main measurements pre and post 3 and 9 months lung resection were: QOL using SF-36v2, Lung Function Tests and Maximal Cardiopulmonary Exercise Test on cycle ergometer.

Results. Out of 61 patients, 53 (50.9% male; 41.3 ±12.9 yrs) underwent surgical resection, but only 44 complete the nine months of follow-up. Two patients died and minor complications occurred in 24.5%. Lobectomy was performed in 83%. Functionally, they were characterized of mild obstruction and diminished exercise capacity. Their QOL were worse than expected for healthy individuals. Surgery resulted in mildly reduction of lung volume and the exercise capacity was not decreased at 3 and 9 months

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Table1

, but in fact 52% improved their exercise performance. QOL improved significantly achieving values considered normal for general population. The results are similar for lobectomy and pneumonectomy.

Conclusion. Lung resection resulted in non-clinical significant drop of lung function and the patients maintained exercise capacity with important benefits in QOL at 3 and 9 months after surgery.

  • Bronchiectasis
  • Quality of life
  • Lung function testing
  • © 2014 ERS
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Physiological and sensorial effects of surgical treatment for bronchiectasis
Camilla Carlini Vallilo, Andre Luis Pereira de Albuquerque, Ricardo Mingarini Terra, João Marcos Salge, Milena Mako Suesada, Marcia Cistina Augusto, Fabiane Polisel, Edilene de Morais, Paulo Manuel Pêgo-Fernendes
European Respiratory Journal Sep 2014, 44 (Suppl 58) 1921;

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Physiological and sensorial effects of surgical treatment for bronchiectasis
Camilla Carlini Vallilo, Andre Luis Pereira de Albuquerque, Ricardo Mingarini Terra, João Marcos Salge, Milena Mako Suesada, Marcia Cistina Augusto, Fabiane Polisel, Edilene de Morais, Paulo Manuel Pêgo-Fernendes
European Respiratory Journal Sep 2014, 44 (Suppl 58) 1921;
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