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Table of Contents

01 August 2014; volume 44, issue 2

Electronic Resources

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    European Respiratory Journal 44 (2) E44; Published 31 July 2014
    • ERJ Podcast

Editorials

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    A global registry for idiopathic pulmonary fibrosis: the time is now
    Christopher J. Ryerson, Tamera J. Corte, Harold R. Collard, Luca Richeldi
    European Respiratory Journal 44 (2) 273-276; DOI: 10.1183/09031936.00051914 Published 31 July 2014
    • Disclosures
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    Why is COPD phenotyping like sorting diamonds?
    Peter G. Gibson, Vanessa M. McDonald
    European Respiratory Journal 44 (2) 277-279; DOI: 10.1183/09031936.00091214 Published 31 July 2014
    • Disclosures
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    The natural history of COPD: confirming and going beyond Fletcher and Peto
    Albert Miller, Jonathan M. Raskin
    European Respiratory Journal 44 (2) 280-283; DOI: 10.1183/09031936.00079514 Published 31 July 2014
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    Should we exercise caution with benzodiazepine use in patients with COPD?
    Robert Rodriguez-Roisin, Judith Garcia-Aymerich
    European Respiratory Journal 44 (2) 284-286; DOI: 10.1183/09031936.00071014 Published 31 July 2014
    • Disclosures
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    Hypersensitivity pneumonitis and pulmonary hypertension: how the breeze affects the squeeze
    Steven D. Nathan
    European Respiratory Journal 44 (2) 287-288; DOI: 10.1183/09031936.00061214 Published 31 July 2014
    • Disclosures
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    Pleuroparenchymal fibroelastosis: one more walk on the wild side of drugs?
    Philippe Camus, Jan von der Thüsen, David M. Hansell, Thomas V. Colby
    European Respiratory Journal 44 (2) 289-296; DOI: 10.1183/09031936.00088414 Published 31 July 2014
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    The new Back to Basics section: emerging concepts in basic and translational medicine
    Melanie Königshoff
    European Respiratory Journal 44 (2) 297-298; DOI: 10.1183/09031936.00107914 Published 31 July 2014
    • Disclosures
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    The best laid schemes of airway repair
    Emma L. Rawlins, Adam Giangreco
    European Respiratory Journal 44 (2) 299-301; DOI: 10.1183/09031936.00088014 Published 31 July 2014

From the Museum

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    From the Museum: the Art of Thinking. Part Six: Perception
    Tom Kotsimbos
    European Respiratory Journal 44 (2) 302-303; DOI: 10.1183/09031936.00440214 Published 31 July 2014

Perspective

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    Integrated care pathways for airway diseases (AIRWAYS-ICPs)
    J. Bousquet, A. Addis, I. Adcock, I. Agache, A. Agusti, A. Alonso, I. Annesi-Maesano, J.M. Anto, C. Bachert, C.E. Baena-Cagnani, C. Bai, A. Baigenzhin, C. Barbara, P.J. Barnes, E.D. Bateman, L. Beck, A. Bedbrook, E.H. Bel, O. Benezet, K.S. Bennoor, M. Benson, M. Bernabeu-Wittel, M. Bewick, C. Bindslev-Jensen, H. Blain, F. Blasi, M. Bonini, S. Bonini, L.P. Boulet, A. Bourdin, R. Bourret, P.J. Bousquet, C.E. Brightling, A. Briggs, J. Brozek, R. Buhl, A. Bush, D. Caimmi, M. Calderon, P. Calverley, P.A. Camargos, T. Camuzat, G.W. Canonica, K.H. Carlsen, T.B. Casale, M. Cazzola, A.M. Cepeda Sarabia, A. Cesario, Y.Z. Chen, E. Chkhartishvili, N.H. Chavannes, R. Chiron, A. Chuchalin, K.F. Chung, L. Cox, G. Crooks, M.G. Crooks, A.A. Cruz, A. Custovic, R. Dahl, S.E. Dahlen, F. De Blay, T. Dedeu, D. Deleanu, P. Demoly, P. Devillier, A. Didier, A.T. Dinh-Xuan, R. Djukanovic, D. Dokic, H. Douagui, R. Dubakiene, S. Eglin, F. Elliot, R. Emuzyte, L. Fabbri, A. Fink Wagner, M. Fletcher, W.J. Fokkens, J. Fonseca, A. Franco, P. Frith, A. Furber, M. Gaga, J. Garcés, J. Garcia-Aymerich, A. Gamkrelidze, S. Gonzales-Diaz, F. Gouzi, M.A. Guzmán, T. Haahtela, D. Harrison, M. Hayot, L.G. Heaney, J. Heinrich, P.W. Hellings, J. Hooper, M. Humbert, M. Hyland, G. Iaccarino, D. Jakovenko, J.R. Jardim, C. Jeandel, C. Jenkins, S.L. Johnston, O. Jonquet, G. Joos, K.S. Jung, O. Kalayci, S. Karunanithi, T. Keil, N. Khaltaev, V. Kolek, M.L. Kowalski, I. Kull, P. Kuna, V. Kvedariene, L.T. Le, K.C. Lodrup Carlsen, R. Louis, W. MacNee, A. Mair, I. Majer, P. Manning, E. de Manuel Keenoy, M.R. Masjedi, E. Melen, E. Melo-Gomes, A. Menzies-Gow, G. Mercier, J. Mercier, J.P. Michel, N. Miculinic, F. Mihaltan, B. Milenkovic, M. Molimard, I. Momas, A. Montilla-Santana, M. Morais-Almeida, M. Morgan, M. N'Diaye, S. Nafti, K. Nekam, A. Neou, L. Nicod, R. O'Hehir, K. Ohta, P. Paggiaro, S. Palkonen, S. Palmer, N.G. Papadopoulos, A. Papi, G. Passalacqua, I. Pavord, B. Pigearias, D. Plavec, D.S. Postma, D. Price, K.F. Rabe, F. Radier Pontal, J. Redon, S. Rennard, J. Roberts, J.M. Robine, J. Roca, N. Roche, F. Rodenas, A. Roggeri, C. Rolland, J. Rosado-Pinto, D. Ryan, B. Samolinski, M. Sanchez-Borges, H.J. Schünemann, A. Sheikh, M. Shields, N. Siafakas, Y. Sibille, T. Similowski, I. Small, O. Sola-Morales, T. Sooronbaev, R. Stelmach, P.J. Sterk, T. Stiris, P. Sud, V. Tellier, T. To, A. Todo-Bom, M. Triggiani, R. Valenta, A.L. Valero, A. Valiulis, E. Valovirta, E. Van Ganse, O. Vandenplas, T. Vasankari, J. Vestbo, G. Vezzani, G. Viegi, L. Visier, C. Vogelmeier, T. Vontetsianos, R. Wagstaff, U. Wahn, B. Wallaert, B. Whalley, M. Wickman, D.M. Williams, N. Wilson, B.P. Yawn, P.K. Yiallouros, A. Yorgancioglu, O.M. Yusuf, H.J. Zar, N. Zhong, M. Zidarn, T. Zuberbier
    European Respiratory Journal 44 (2) 304-323; DOI: 10.1183/09031936.00014614 Published 31 July 2014
    • ERJ Podcast
    • Disclosures

Original Articles

COPD

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    Disease progression in young patients with COPD: rethinking the Fletcher and Peto model
    Pablo Sanchez-Salcedo, Miguel Divo, Ciro Casanova, Victor Pinto-Plata, Juan P. de-Torres, Claudia Cote, Carlos Cabrera, Jorge Zagaceta, Roberto Rodriguez-Roisin, Javier J. Zulueta, Jose Maria Marin, Bartolome Celli
    European Respiratory Journal 44 (2) 324-331; DOI: 10.1183/09031936.00208613 Published 31 July 2014
    • CME questions
    • Supplementary material
    • Supplementary material
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    Benzodiazepine drug use and adverse respiratory outcomes among older adults with COPD
    Nicholas T. Vozoris, Hadas D. Fischer, Xuesong Wang, Anne L. Stephenson, Andrea S. Gershon, Andrea Gruneir, Peter C. Austin, Geoffrey M. Anderson, Chaim M. Bell, Sudeep S. Gill, Paula A. Rochon
    European Respiratory Journal 44 (2) 332-340; DOI: 10.1183/09031936.00008014 Published 31 July 2014
    • Supplementary material
    • Disclosures

Asthma and COPD

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    The clinical and genetic features of COPD-asthma overlap syndrome
    Megan Hardin, Michael Cho, Merry-Lynn McDonald, Terri Beaty, Joe Ramsdell, Surya Bhatt, Edwin J.R. van Beek, Barry J. Make, James D. Crapo, Edwin K. Silverman, Craig P. Hersh
    European Respiratory Journal 44 (2) 341-350; DOI: 10.1183/09031936.00216013 Published 31 July 2014
    • Supplementary material

Asthma

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    Exhaled nitric oxide, nitrite/nitrate levels, allergy, rhinitis and asthma in the EGEA study
    Rachel Nadif, Marta Rava, Brigitte Decoster, Hélène Huyvaert, Nicole Le Moual, Jean Bousquet, Valérie Siroux, Raphaëlle Varraso, Isabelle Pin, Farid Zerimech, Régis Matran
    European Respiratory Journal 44 (2) 351-360; DOI: 10.1183/09031936.00202413 Published 31 July 2014
    • Supplementary material
    • Disclosures
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    Glucocorticoids induce the production of the chemoattractant CCL20 in airway epithelium
    G. Jan Zijlstra, Fatemeh Fattahi, Dennie Rozeveld, Marnix R. Jonker, Nathalie M. Kliphuis, Maarten van den Berge, Machteld N. Hylkema, Nick H.T. ten Hacken, Antoon J.M. van Oosterhout, Irene H. Heijink
    European Respiratory Journal 44 (2) 361-370; DOI: 10.1183/09031936.00209513 Published 31 July 2014
    • Supplementary material
    • Disclosures

Paediatric pulmonology

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    Determinants of baseline lung function and bronchodilator response in 4-year-old children
    Sandra Dom, Joost J. Weyler, Jos H.J. Droste, Margo M. Hagendorens, Elke Dierckx, Chris H. Bridts, Wilfried De Backer, Ellie Oostveen
    European Respiratory Journal 44 (2) 371-381; DOI: 10.1183/09031936.00100813 Published 31 July 2014
    • Supplementary material
    • Disclosures

Bronchiectasis

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    Inhaled antibiotics for stable non-cystic fibrosis bronchiectasis: a systematic review
    Alessandra Monteiro Brodt, Elizabeth Stovold, Linjie Zhang
    European Respiratory Journal 44 (2) 382-393; DOI: 10.1183/09031936.00018414 Published 31 July 2014
    • Supplementary material

Cystic fibrosis

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    Reduced 15-lipoxygenase 2 and lipoxin A4/leukotriene B4 ratio in children with cystic fibrosis
    Fiona C. Ringholz, Paul J. Buchanan, Donna T. Clarke, Roisin G. Millar, Michael McDermott, Barry Linnane, Brian J. Harvey, Paul McNally, Valerie Urbach
    European Respiratory Journal 44 (2) 394-404; DOI: 10.1183/09031936.00106013 Published 31 July 2014
    • Supplementary material

Sleep

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    Obstructive sleep apnoea treatment and fasting lipids: a comparative effectiveness study
    Brendan T. Keenan, Greg Maislin, Bernie Y. Sunwoo, Erna Sif Arnardottir, Nicholas Jackson, Isleifur Olafsson, Sigurdur Juliusson, Richard J. Schwab, Thorarinn Gislason, Bryndis Benediktsdottir, Allan I. Pack
    European Respiratory Journal 44 (2) 405-414; DOI: 10.1183/09031936.00043614 Published 31 July 2014
    • Supplementary material
    • Disclosures

Pulmonary vascular diseases

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    A haemodynamic study of pulmonary hypertension in chronic hypersensitivity pneumonitis
    Rudolf K.F. Oliveira, Carlos A.C. Pereira, Roberta P. Ramos, Eloara V.M. Ferreira, Carolina M.S. Messina, Lilian T. Kuranishi, Andrea Gimenez, Orlando Campos, Célia M.C. Silva, Jaquelina S. Ota-Arakaki
    European Respiratory Journal 44 (2) 415-424; DOI: 10.1183/09031936.00010414 Published 31 July 2014
    • Supplementary material
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    Reliance on end-expiratory wedge pressure leads to misclassification of pulmonary hypertension
    Barbara L. LeVarge, Eugene Pomerantsev, Richard N. Channick
    European Respiratory Journal 44 (2) 425-434; DOI: 10.1183/09031936.00209313 Published 31 July 2014

Tuberculosis

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    Xpert MTB/RIF assay for the diagnosis of extrapulmonary tuberculosis: a systematic review and meta-analysis
    Claudia M. Denkinger, Samuel G. Schumacher, Catharina C. Boehme, Nandini Dendukuri, Madhukar Pai, Karen R. Steingart
    European Respiratory Journal 44 (2) 435-446; DOI: 10.1183/09031936.00007814 Published 31 July 2014
    • Supplementary material
    • Disclosures

Lung biology

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    SFTA3, a novel protein of the lung: three-dimensional structure, characterisation and immune activation
    Martin Schicht, Felix Rausch, Susetta Finotto, Martina Mathews, Anja Mattil, Melanie Schubert, Beate Koch, Maximilian Traxdorf, Christopher Bohr, Dieter Worlitzsch, Wolfgang Brandt, Fabian Garreis, Saadettin Sel, Friedrich Paulsen, Lars Bräuer
    European Respiratory Journal 44 (2) 447-456; DOI: 10.1183/09031936.00179813 Published 31 July 2014
    • Supplementary material

Scientific Assembly Update

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    Paediatrics in Barcelona
    Fabio Midulla, Enrico Lombardi, Bart Rottier, Anders Lindblad, Jonathan Grigg, Kajsa Bohlin, Franca Rusconi, Petr Pohunek, Ernst Eber
    European Respiratory Journal 44 (2) 457-474; DOI: 10.1183/09031936.00046414 Published 31 July 2014
    • Disclosures

Review

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    Bifunctional drugs for the treatment of asthma and chronic obstructive pulmonary disease
    Clive Page, Mario Cazzola
    European Respiratory Journal 44 (2) 475-482; DOI: 10.1183/09031936.00003814 Published 31 July 2014

Series

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    Surgical and nonsurgical approaches to small-size nonsmall cell lung cancer
    Dirk De Ruysscher, Kazuo Nakagawa, Hisao Asamura
    European Respiratory Journal 44 (2) 483-494; DOI: 10.1183/09031936.00020214 Published 31 July 2014
    • Disclosures
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    Pathophysiology of human ventilatory control
    Jerome A. Dempsey, Curtis A. Smith
    European Respiratory Journal 44 (2) 495-512; DOI: 10.1183/09031936.00048514 Published 31 July 2014

Back to Basics

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    Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunities
    Sabari Vallath, Robert E. Hynds, Laura Succony, Sam M. Janes, Adam Giangreco
    European Respiratory Journal 44 (2) 513-522; DOI: 10.1183/09031936.00146413 Published 31 July 2014

Agora

Research letters

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    Pleuroparenchymal fibroelastosis as a late complication of chemotherapy agents
    Caroline Beynat-Mouterde, Guillaume Beltramo, Guillaume Lezmi, Didier Pernet, Clio Camus, Annlyse Fanton, Pascal Foucher, Vincent Cottin, Philippe Bonniaud
    European Respiratory Journal 44 (2) 523-527; DOI: 10.1183/09031936.00214713 Published 31 July 2014
    • Disclosures
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    The effect of roflumilast in addition to LABA/LAMA/ICS treatment in COPD patients
    Wilfried De Backer, Wim Vos, Cedric Van Holsbeke, Samir Vinchurkar, Rita Claes, Annemie Hufkens, Paul M. Parizel, Lieven Bedert, Jan De Backer
    European Respiratory Journal 44 (2) 527-529; DOI: 10.1183/09031936.00011714 Published 31 July 2014
    • Disclosures
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    The association between lung function and arterial stiffness in young childhood
    Jacobien B. Eising, Cornelis K. van der Ent, Annemieke M.V. Evelein, Cuno S.P.M. Uiterwaal
    European Respiratory Journal 44 (2) 530-532; DOI: 10.1183/09031936.00006814 Published 31 July 2014
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    Pulmonary radioaerosol mucociliary clearance in primary ciliary dyskinesia
    Woolf T. Walker, Aneurin Young, Michael Bennett, Matthew Guy, Mary Carroll, John Fleming, Joy Conway, Jane S. Lucas
    European Respiratory Journal 44 (2) 533-535; DOI: 10.1183/09031936.00011814 Published 31 July 2014
    • Disclosures
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    Severe influenza A H7N9 pneumonia with rapid virological response to intravenous zanamivir
    Pak-Leung Ho, Wai-Ching Sin, Jasper Fuk-Woo Chan, Vincent Chi-Chung Cheng, Kwok-Hung Chan
    European Respiratory Journal 44 (2) 535-537; DOI: 10.1183/09031936.00006414 Published 31 July 2014
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    Tuberculosis diagnostics: which target product profiles should be prioritised?
    Sandra V. Kik, Claudia M. Denkinger, Martina Casenghi, Caroline Vadnais, Madhukar Pai
    European Respiratory Journal 44 (2) 537-540; DOI: 10.1183/09031936.00027714 Published 31 July 2014
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    6-year follow-up of 522 HIV-positive individuals screened for Mycobacterium tuberculosis infection in Denmark
    Christian Soborg, Morten Ruhwald, Peter H. Andersen, Pernille Ravn
    European Respiratory Journal 44 (2) 540-543; DOI: 10.1183/09031936.00170913 Published 31 July 2014
    • Disclosures
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    Tuberculosis elimination: dream or reality? The case of Cyprus
    Constantia Voniatis, Giovanni Battista Migliori, Michael Voniatis, Andreas Georgiou, Lia D’Ambrosio, Rosella Centis, Mario C. Raviglione
    European Respiratory Journal 44 (2) 543-546; DOI: 10.1183/09031936.00044314 Published 31 July 2014

Correspondence

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    Cytokines in pulmonary arterial hypertension: consider sensitivity when using multiplex technology
    Denis Monneret
    European Respiratory Journal 44 (2) 547-549; DOI: 10.1183/09031936.00000114 Published 31 July 2014
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    Is auto-servoventilation unnecessary in patients with heart failure and apnoea?
    Dany Jaffuel, Nicolas Combes, Nicolas Molinari, Philippe Berdagué, Samir Jaber
    European Respiratory Journal 44 (2) 549-551; DOI: 10.1183/09031936.00024414 Published 31 July 2014
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    Is auto-servoventilation unnecessary in patients with heart failure and apnoea?
    Michael Arzt, Michael Pfeifer, Stephan Schroll
    European Respiratory Journal 44 (2) 551-553; DOI: 10.1183/09031936.00057114 Published 31 July 2014
    • Disclosures
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    Sex matters in pulmonary arterial hypertension
    Robert Naeije, Michele D’Alto
    European Respiratory Journal 44 (2) 553-554; DOI: 10.1183/09031936.00054514 Published 31 July 2014

Author Correction

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    “Umeclidinium in patients with COPD: a randomised, placebo-controlled study.” Roopa Trivedi, Nathalie Richard, Rashmi Mehta and Alison Church. Eur Respir J 2014; 43: 72–81.
    European Respiratory Journal 44 (2) 555; DOI: 10.1183/09031936.50033213 Published 31 July 2014

Erratum

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    “Prolonged shedding of rhinovirus and re-infection in adults with respiratory tract illness.” Kalina T. Zlateva, Jutte J.C. de Vries, Frank E.J. Coenjaerts, Anton M. van Loon, Theo Verheij, Paul Little, Christopher C. Butler, Herman Goossens, Margareta Ieven and Eric C.J. Claas on behalf of the GRACE Study Group. Eur Respir J 2014; 44: 169–177.
    European Respiratory Journal 44 (2) 556; DOI: 10.1183/09031936.50172113 Published 31 July 2014
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