Abstract
Background: Endobronchial ultrasonography using a guide sheath (EBUS-GS) is a method established for pulmonary lesions however, there are only few reports regarding lesions with ground glass opacity (GGO).
Objective: To assess the diagnostic accuracy of GS for lesions with GGO.
Methods: Between January 2010 and January 2013, 48 patients with a confirmed diagnosis of lung cancer underwent either surgery or GS. GS was performed using an endoscopic ultrasound system, which was equipped with a 20-MHz mechanical radial-type probe with an external diameter of 1.4 mm with GS. Bronchoscope with a working channel diameter of 2.0 mm was used. Three to 5 biopsy and brushing samples were taken for all patients. Subjects were then categorized by the ratio of solid area and GGO (longest diameter of tumor with mediastinal window / longest diameter of tumor with lung window ×100) on CT as pure GGO or mixed GGO (<25%, 25-50%, >50%).
Results: The total diagnostic yield of GS in patients with GGO was 77.1%. Cytological diagnosis was 54.2%, and tissue diagnosis was 70.8%. The diagnostic accuracy when the position of the probe was outside the lesion was invisible was 0%, adjacent to the lesion was 71.4%, and within the lesion was 83.9%. The diagnostic accuracy visualized as typeIIa (hyperechoic points without open vessels) was 77.3%, typeIIb (hyperechoic points with open vessels) was 82.6%.
Conclusions: GS for the diagnostic yield in patients with GGO was 77.1%. Increasing the solid part in the lesion, the population of typeIIb, within, and diagnostic yield increased.
- © 2013 ERS
