Abstract
Introduction:
There is a lot of evidence that smoking is an aggravating factor in asthma.
Objective:
Evaluate smoking cessation abstinence rates in smokers with asthma treated with drug therapy, combined with brief counseling.
Material and Methods:
It conducted a descriptive, longitudinal and prospective study, from January 2010 to October 2012. All patients underwent clinical history of smoking. A total of seven visits were conducted (baseline, and at weeks 2nd and 4th and at months 2nd, 3rd, 6th and 12th). Smoking abstinence was confirmed by validation of exhaled CO (<10 ppm).
Results:
We included 128 patients, 98 (76.5%) women and 30 (23.5%) males, mean age: 41.14 (± 10.61) years. Mean number of cigarettes smoked per day: 23.76 (± 9.33). FTND-score Mean: 7.08 (± 1.20), mean CO: 25.26(± 12, 64)ppm. 53% of the subjects smoked their first cigarette five minutes after waking up and 32% 30 minutes after waking up.
Considering the treatment used, the abstinence rate at week 52 was:
Vareniclina: 58%. Nicotine patches: 49% and bupropion: 45%.
Conclusions:
• More females than males among the participants.
• The average consumption of cigarettes per day is high.
• Physical dependence severe, more than 7 points in the FTND-score and 88% smoked their first cigarette within half an hour.
• The highest abstinence rate was obtained by varenicline (58%), then nicotine patches (49%) and bupropion (45%).
• All medications were well tolerated and safe.
- © 2013 ERS
