Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • ERS Guidelines
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • Peer reviewer login
  • Alerts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • ERS Guidelines
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • Peer reviewer login
  • Alerts
  • Subscriptions

Prognosis of pneumocystis jirovecii pneumonia in non-HIV patients

Zehra Nur Töreyin, Pervin Ekren, Ayse Caner, Seray Töz, Alev Gürgün, Hatice Uluer, Feza Bacakoglu
European Respiratory Journal 2013 42: P2759; DOI:
Zehra Nur Töreyin
1Department of Chest Diseases, Ege University Medical Faculty, Izmir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pervin Ekren
1Department of Chest Diseases, Ege University Medical Faculty, Izmir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ayse Caner
2Department of Parasitology, Ege University Medical Faculty, Izmir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Seray Töz
2Department of Parasitology, Ege University Medical Faculty, Izmir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alev Gürgün
1Department of Chest Diseases, Ege University Medical Faculty, Izmir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hatice Uluer
3Department of Biostatistics and Medical Informatics, Ege University Medical Faculty, Izmir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Feza Bacakoglu
1Department of Chest Diseases, Ege University Medical Faculty, Izmir, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • PDF
Loading

Abstract

Pneumocystis jirovecii pneumonia (PcP) is an opportunistic infection which can have different prognosis and progression among patients with HIV and non-HIV. It is still controversial whether Cytomegalovirus (CMV) co-infection worsens the prognosis or not. In this retrospective study, we aimed to investigate the effect of CMV co-infection in the prognosis of patients with PcP.

In the study 20 immunocompromised non-HIV PcP (median age 54.3±15.3 yrs, 13 males) patients who were admitted to our clinic from January 2009 to December 2012 were included. Demographic characteristics of the patients, immunosupressive therapy, anti-microbial prophylaxis, clinical, laboratory, radiological findings, the diagnostic method, the data for the presence and treatment of co-infection and respiratory failure were recorded.

On admission, 16 (80%) of the patients were on corticosteroid treatment. The median APACHE II Score was 19.0 (9-40), PaO2/FiO2 ratio was 147.5 (78-471). PcP diagnosis was made by microscopic examination in 2 cases and by PCR in 14 cases while in 4 cases both method was used. During follow-up, co-infection occured in 17 (85%) of the patients. 16 (80%) of them developed ARDS, 17 (85%) of the patients required invasive mechanical ventilation and 14 (70%) of them died. Mortality rates were higher in patients who developed ARDS, were intubated and co-infected (p=0.01, p=0.018, p=0.018, respectively). Twelwe (70.8%) of the patients had CMV co-infection. Progression to ARDS and intubation rates were higher (p=0.036 and p=0.049, respectively) in these patients.

In conclusion; among the non-HIV patients with PcP, progression to ARDS and mortality rates are higher in the presence of co-infection especially with CMV.

  • Immunosuppression
  • Pneumonia
  • Infections
  • © 2013 ERS
Previous
Back to top
Vol 42 Issue Suppl 57 Table of Contents
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Prognosis of pneumocystis jirovecii pneumonia in non-HIV patients
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Prognosis of pneumocystis jirovecii pneumonia in non-HIV patients
Zehra Nur Töreyin, Pervin Ekren, Ayse Caner, Seray Töz, Alev Gürgün, Hatice Uluer, Feza Bacakoglu
European Respiratory Journal Sep 2013, 42 (Suppl 57) P2759;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Prognosis of pneumocystis jirovecii pneumonia in non-HIV patients
Zehra Nur Töreyin, Pervin Ekren, Ayse Caner, Seray Töz, Alev Gürgün, Hatice Uluer, Feza Bacakoglu
European Respiratory Journal Sep 2013, 42 (Suppl 57) P2759;
del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo
Full Text (PDF)

Jump To

  • Article
  • Info & Metrics
  • PDF
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

  • H1N1pdm09 is an independent risk factor for severe influenza
  • Acutely lethal H1N1 influenza A virus infection alters the murine alveolar type II cell surfactant lipidome
  • Treatment outcome in patients with chronic pulmonary aspergillosis by azole-resistant aspergillus fumigatus
Show more 10.1 Respiratory Infections

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Publication ethics and malpractice
  • Submit a manuscript

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2023 by the European Respiratory Society