Table of Contents

Original Article

• COPD

  • Open Access

    The impact of COPD on health status: findings from the BOLD study

    Christer Janson, Guy Marks, Sonia Buist, Louisa Gnatiuc, Thorarinn Gislason, Mary Ann McBurnie, Rune Nielsen, Michael Studnicka, Brett Toelle, Bryndis Benediktsdottir, Peter Burney

    European Respiratory Journal 42 (6) 1472-1483; DOI: 10.1183/09031936.00153712 Published 30 November 2013

    • Disclosures
  • Open Access

    Dual bronchodilation with QVA149 versus single bronchodilator therapy: the SHINE study

    Eric D. Bateman, Gary T. Ferguson, Neil Barnes, Nicola Gallagher, Yulia Green, Michelle Henley, Donald Banerji

    European Respiratory Journal 42 (6) 1484-1494; DOI: 10.1183/09031936.00200212 Published 30 November 2013

    • Supplementary material
    • Disclosures

• Asthma

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    Metabolic syndrome and incidence of asthma in adults: the HUNT study

    Ben Michael Brumpton, Carlos Arturo Camargo Jr, Pål Richard Romundstad, Arnulf Langhammer, Yue Chen, Xiao-Mei Mai

    European Respiratory Journal 42 (6) 1495-1502; DOI: 10.1183/09031936.00046013 Published 30 November 2013

    • Supplementary material
    • Disclosures

• Lung Function

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    Dose-dependent association of smoking and bronchial hyperresponsiveness

    Maria Juusela, Paula Pallasaho, Eva Rönmark, Seppo Sarna, Anssi Sovijärvi, Bo Lundbäck

    European Respiratory Journal 42 (6) 1503-1512; DOI: 10.1183/09031936.00073712 Published 30 November 2013
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    Respiratory impedance in healthy subjects: baseline values and bronchodilator response

    Ellie Oostveen, Krisztina Boda, Chris P.M. van der Grinten, Alan L. James, Sally Young, Hans Nieland, Zoltán Hantos

    European Respiratory Journal 42 (6) 1513-1523; DOI: 10.1183/09031936.00126212 Published 30 November 2013

    • Supplementary material

• Epidemiology

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    Periodontitis is related to lung volumes and airflow limitation: a cross-sectional study

    Birte Holtfreter, Stefanie Richter, Thomas Kocher, Marcus Dörr, Henry Völzke, Till Ittermann, Anne Obst, Christoph Schäper, Ulrich John, Peter Meisel, Anne Grotevendt, Stephan B. Felix, Ralf Ewert, Sven Gläser

    European Respiratory Journal 42 (6) 1524-1535; DOI: 10.1183/09031936.00109112 Published 30 November 2013

    • Supplementary material
    • Disclosures

• Paediatric Pneumology

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    Pulmonary gas transfer in children and adolescents born extremely preterm

    Emma Satrell, Ola Røksund, Einar Thorsen, Thomas Halvorsen

    European Respiratory Journal 42 (6) 1536-1544; DOI: 10.1183/09031936.00027112 Published 30 November 2013

    • Supplementary material

• Cystic Fibrosis

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    Association of lung function, chest radiographs and clinical features in infants with cystic fibrosis

    Margaret Rosenfeld, Philip M. Farrell, Margaret Kloster, Jonathan O. Swanson, Thuy Vu, Lyndia Brumback, James D. Acton, Robert G. Castile, Andrew A. Colin, Carol K. Conrad, Meeghan A. Hart, Gwendolyn S. Kerby, Peter W. Hiatt, Peter J. Mogayzel, Robin C. Johnson, Stephanie D. Davis

    European Respiratory Journal 42 (6) 1545-1552; DOI: 10.1183/09031936.00138412 Published 30 November 2013

    • Disclosures
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    CFTR dysfunction induces vascular endothelial growth factor synthesis in airway epithelium

    Clémence Martin, Nathalie Coolen, Yongzheng Wu, Guiti Thévenot, Lhousseine Touqui, Virginie Prulière-Escabasse, Jean-François Papon, André Coste, Estelle Escudier, Daniel J. Dusser, Isabelle Fajac, Pierre-Régis Burgel

    European Respiratory Journal 42 (6) 1553-1562; DOI: 10.1183/09031936.00164212 Published 30 November 2013

    • Supplementary material
    • Disclosures

• Sleep Medicine

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    A urine biomarker for severe obstructive sleep apnoea patients: lipocalin-type prostaglandin D synthase

    Yuichi Chihara, Kazuo Chin, Kosuke Aritake, Yuka Harada, Yoshiro Toyama, Kimihiko Murase, Chikara Yoshimura, Takefumi Hitomi, Toru Oga, Michiaki Mishima, Yoshihiro Urade

    European Respiratory Journal 42 (6) 1563-1574; DOI: 10.1183/09031936.00133512 Published 30 November 2013

    • Supplementary material
    • Disclosures

• Pulmonary Vascular Diseases

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    Severely reduced diffusion capacity in idiopathic pulmonary arterial hypertension: patient characteristics and treatment responses

    Pia Trip, Esther J. Nossent, Frances S. de Man, Inge A.H. van den Berk, Anco Boonstra, Herman Groepenhoff, Edward M. Leter, Nico Westerhof, Katrien Grünberg, Harm-Jan Bogaard, Anton Vonk-Noordegraaf

    European Respiratory Journal 42 (6) 1575-1585; DOI: 10.1183/09031936.00184412 Published 30 November 2013

    • Disclosures
    • CME questions
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    Zero reference level for right heart catheterisation

    Gabor Kovacs, Alexander Avian, Andrea Olschewski, Horst Olschewski

    European Respiratory Journal 42 (6) 1586-1594; DOI: 10.1183/09031936.00050713 Published 30 November 2013

    • Supplementary material
    • Disclosures

• Respiratory Infections

  • Open Access

    Aetiology of paediatric pneumonia after the introduction of pneumococcal conjugate vaccine

    Mohamed A. Elemraid, Andrew D. Sails, Gary J.A. Eltringham, John D. Perry, Stephen P. Rushton, David A. Spencer, Matthew F. Thomas, Katherine M. Eastham, Fiona Hampton, Andrew R. Gennery, Julia E. Clark on behalf of the North East of England Paediatric Respiratory Infection Study Group

    European Respiratory Journal 42 (6) 1595-1603; DOI: 10.1183/09031936.00199112 Published 30 November 2013

    • Disclosures
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    The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: an NTM-NET collaborative study

    Wouter Hoefsloot, Jakko van Ingen, Claire Andrejak, Kristian Ängeby, Rosine Bauriaud, Pascale Bemer, Natalie Beylis, Martin J. Boeree, Juana Cacho, Violet Chihota, Erica Chimara, Gavin Churchyard, Raquel Cias, Rosa Daza, Charles L. Daley, P.N. Richard Dekhuijzen, Diego Domingo, Francis Drobniewski, Jaime Esteban, Maryse Fauville-Dufaux, Dorte Bek Folkvardsen, Noel Gibbons, Enrique Gómez-Mampaso, Rosa Gonzalez, Harald Hoffmann, Po-Ren Hsueh, Alexander Indra, Tomasz Jagielski, Frances Jamieson, Mateja Jankovic, Eefje Jong, Joseph Keane, Wo-Jung Koh, Berit Lange, Sylvia Leao, Rita Macedo, Turid Mannsåker, Theodore K. Marras, Jeannette Maugein, Heather J. Milburn, Tamas Mlinkó, Nora Morcillo, Kozo Morimoto, Dimitrios Papaventsis, Elia Palenque, Mar Paez-Peña, Claudio Piersimoni, Monika Polanová, Nalin Rastogi, Elvira Richter, Maria Jesus Ruiz-Serrano, Anabela Silva, M. Pedro da Silva, Hulya Simsek, Dick van Soolingen, Nora Szabó, Rachel Thomson, Teresa Tórtola Fernandez, Enrico Tortoli, Sarah E. Totten, Greg Tyrrell, Tuula Vasankari, Miguel Villar, Renata Walkiewicz, Kevin L. Winthrop, Dirk Wagner for the Nontuberculous Mycobacteria Network European Trials Group (NTM-NET)

    European Respiratory Journal 42 (6) 1604-1613; DOI: 10.1183/09031936.00149212 Published 30 November 2013

    • Supplementary material

• Tuberculosis

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    Clarithromycin increases linezolid exposure in multidrug-resistant tuberculosis patients

    Mathieu S. Bolhuis, Richard van Altena, Dick van Soolingen, Wiel C.M. de Lange, Donald R.A. Uges, Tjip S. van der Werf, Jos G.W. Kosterink, Jan-Willem C. Alffenaar

    European Respiratory Journal 42 (6) 1614-1621; DOI: 10.1183/09031936.00001913 Published 30 November 2013

    • Disclosures

• Interstitial Lung Diseases

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    Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial

    Ganesh Raghu, Rachel Million-Rousseau, Adele Morganti, Loїc Perchenet, Juergen Behr, the MUSIC Study Group

    European Respiratory Journal 42 (6) 1622-1632; DOI: 10.1183/09031936.00104612 Published 30 November 2013

    • Supplementary material
    • Disclosures
  • Open Access

    Ex vivo micro-computed tomography analysis of bleomycin-induced lung fibrosis for preclinical drug evaluation

    Chris J. Scotton, Brian Hayes, Robert Alexander, Arnab Datta, Ellen J. Forty, Paul F. Mercer, Andy Blanchard, Rachel C. Chambers

    European Respiratory Journal 42 (6) 1633-1645; DOI: 10.1183/09031936.00182412 Published 30 November 2013

    • Supplementary material
    • Disclosures
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    In vivo probe-based confocal laser endomicroscopy in amiodarone-related pneumonia

    Mathieu Salaün, Francis Roussel, Geneviève Bourg-Heckly, Christine Vever-Bizet, Stéphane Dominique, Anne Genevois, Vincent Jounieaux, Gérard Zalcman, Emmanuel Bergot, Jean-Michel Vergnon, Luc Thiberville

    European Respiratory Journal 42 (6) 1646-1658; DOI: 10.1183/09031936.00191911 Published 30 November 2013

    • Supplementary material

• Lung Cancer

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    Volumetric computed tomography screening for lung cancer: three rounds of the NELSON trial

    Nanda Horeweg, Carlijn M. van der Aalst, Rozemarijn Vliegenthart, Yingru Zhao, Xueqian Xie, Ernst Th. Scholten, Willem Mali, Erik Thunnissen, Carla Weenink, Harry J.M. Groen, Jan-Willem J. Lammers, Kristiaan Nackaerts, Joost van Rosmalen, Matthijs Oudkerk, Harry J. de Koning

    European Respiratory Journal 42 (6) 1659-1667; DOI: 10.1183/09031936.00197712 Published 30 November 2013

    • Supplementary material
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    Characteristics and outcome of patients with second primary lung cancer

    Niels Reinmuth, Andreas Stumpf, Patrick Stumpf, Thomas Muley, Sonja Kobinger, Hans Hoffmann, Felix J.F. Herth, Philipp A. Schnabel, Arne Warth, Helge Bischoff, Michael Thomas

    European Respiratory Journal 42 (6) 1668-1676; DOI: 10.1183/09031936.00022512 Published 30 November 2013

• Lung Biology

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    Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice

    Loes E.M. Kistemaker, I.S.T. Bos, Machteld N. Hylkema, Martijn C. Nawijn, Pieter S. Hiemstra, Jürgen Wess, Herman Meurs, Huib A.M. Kerstjens, Reinoud Gosens

    European Respiratory Journal 42 (6) 1677-1688; DOI: 10.1183/09031936.00112412 Published 30 November 2013

    • Supplementary material
    • Disclosures