Figures
- Figure 1–
Bland–Altman plots for a) test-retest and b) interobserver reliability.
- Figure 2–
The relationship between 4-m gait speed (4MGS) and a) incremental shuttle walk (ISW) distance; b) St George's Respiratory Questionnaire (SGRQ) total score; c) forced expiratory volume in 1 s (FEV1) % predicted.
Tables
- Table 1– Baseline characteristics of study subjects
Subjects 586 Age years 70 (63–76) Sex male/female 372/214 Height m 1.67 (1.58–1.73) Weight kg 73.0 (61.8–86.9) Body mass index kg·m−2 26.8 (23.2–31.2) FEV1 % predicted 46 (29–61) MRC dyspnoea score 3 (2–4) ISW test m 190 (100–293) ISW test % predicted 31 (16–49) SGRQ Symptoms 68.6 (52.4–81.2) Activity 72.8 (59.5–87.3) Impact 37.1 (24.5–52.8) Total 53.7 (41.4–66.4) Charlson index 1 (1–2) COTE index 0 (0–1) Exacerbations in previous year 2 (1–3) Hospital days in previous year 0 (0–4.25) Gait speed m·s−1 0.89 (0.74–1.05) Data are presented as n or median (interquartile range). FEV1: forced expiratory volume in 1 s; MRC: Medical Research Council; ISW: incremental shuttle walk; SGRQ: St George’s Respiratory Questionnaire; COTE: chronic obstructive pulmonary disease-specific comorbidity test.
- Table 2– Spearman's rank correlation (ρ) to compare the relationship between 4-m gait speed and other health outcome measurements
ρ p-value Age -0.21 <0.001 Height 0.03 0.40 Weight 0.01 0.86 BMI -0.09 0.03 FEV1 % predicted 0.10 0.01 MRC dyspnoea score -0.55 <0.001 ISW test 0.78 <0.001 ISW test % predicted 0.72 <0.001 SGRQ Symptoms -0.15 0.007 Activity -0.51 <0.001 Impact -0.38 <0.001 Total -0.44 <0.001 Charlson index -0.12 0.004 COTE index -0.09 0.03 BMI: body mass index; FEV1: forced expiratory volume in 1 s; MRC: Medical Research Council; ISW: incremental shuttle walk; SGRQ: St George’s Respiratory Questionnaire; COTE: chronic obstructive pulmonary disease-specific comorbidity test.
- Table 3– A comparison between chronic obstructive pulmonary disease (COPD) patients with low or normal 4-m gait speed (4MGS)
Gait speed p-value Slow Normal Subjects 193 393 Age years 73 (64–78) 69 (63–75) <0.001 Sex male/female 100/93 221/172 0.33 Height m 1.65 (1.58–1.74) 1.58 (1.41–1.67) 0.72 Weight kg 74.6 (61.0–89.0) 72.1 (62.0–86.0) 0.46 BMI kg·m−2 28.4 (23.9–32.5) 26.3 (23.0–30.2) 0.01 FEV1 % predicted 46 (28–61) 46 (30–61) 0.37 MRC dyspnoea score 4 (4–5) 3 (2–4) <0.001 ISW distance m 80 (40–120) 250 (160–350) <0.001 ISW % predicted 14 (7–24) 41 (28–57) <0.001 SGRQ Symptoms 71.5 (54.3–82.2) 67.8 (51.6–80.2) 0.11 Activity 85.8 (72.8–92.5) 66.3 (53.5–79.8) <0.001 Impact 47.9 (32.1–58.4) 34.0 (22.3–47.1) <0.001 Total 63.1 (48.9–71.6) 49.6 (387–61.1) <0.001 Charlson index 1 (1–3) 1 (1–2) 0.02 COTE index 0 (0–1) 0 (0–1) 0.82 Exacerbations 2 (1–4) 2 (1–3) 0.77 Hospital days 1 (0–7) 0 (0–4) 0.004 Gait speed m·s−1 0.67 (0.56–0.74) 0.99 (0.89–1.12) <0.001 Data are presented as n or median (interquartile range), unless otherwise stated. BMI: body mass index; FEV1: forced expiratory volume in 1 s; MRC: Medical Research Council; ISW: incremental shuttle walk; SGRQ: St George’s Respiratory Questionnaire; COTE: chronic obstructive pulmonary disease-specific comorbidity test.
Disclosures
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