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Resistance to fluoroquinolones and second-line injectable drugs: impact on multidrug-resistant TB outcomes

Dennis Falzon, Neel Gandhi, Giovanni B. Migliori, Giovanni Sotgiu, Helen S. Cox, Timothy H. Holtz, Maria-Graciela Hollm-Delgado, Salmaan Keshavjee, Kathryn DeRiemer, Rosella Centis, Lia D'Ambrosio, Christoph G. Lange, Melissa Bauer, Dick Menzies on behalf of the Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB
European Respiratory Journal 2013 42: 156-168; DOI: 10.1183/09031936.00134712
Dennis Falzon
1Stop TB Dept, World Health Organization, Geneva, Switzerland
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Neel Gandhi
2Divisions of General Internal Medicine, Infectious Diseases and Epidemiology, Albert Einstein College of Medicine, New York, NY
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Giovanni B. Migliori
3World Health Organization Collaborating Centre for Tuberculosis and Lung Diseases, Fondazione S. Maugeri, Care and Research Institute, Tradate
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Giovanni Sotgiu
4Dept of Biomedical Sciences, University of Sassari, Sassari, Italy
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Helen S. Cox
5Médecins Sans Frontières, Cape Town, South Africa
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Timothy H. Holtz
6US Centers for Disease Control and Prevention, HIV/STD Research Program, Bangkok, Thailand
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Maria-Graciela Hollm-Delgado
7Montreal Chest Institute, McGill University, Montreal, QC, Canada
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Salmaan Keshavjee
8Dept of Global Health and Social Medicine, Harvard Medical School, Boston, MA
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Kathryn DeRiemer
9School of Medicine, University of California Davis, Davis, CA, USA
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Rosella Centis
3World Health Organization Collaborating Centre for Tuberculosis and Lung Diseases, Fondazione S. Maugeri, Care and Research Institute, Tradate
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Lia D'Ambrosio
3World Health Organization Collaborating Centre for Tuberculosis and Lung Diseases, Fondazione S. Maugeri, Care and Research Institute, Tradate
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Christoph G. Lange
10Clinical Infectious Diseases, Tuberculosis Center Borstel, Borstel, Germany
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Melissa Bauer
7Montreal Chest Institute, McGill University, Montreal, QC, Canada
11Dept of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC
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Dick Menzies
7Montreal Chest Institute, McGill University, Montreal, QC, Canada
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  • For correspondence: Dick.Menzies@McGill.ca
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Article Information

vol. 42 no. 1 156-168
DOI 
https://doi.org/10.1183/09031936.00134712
PubMed 
23100499

Published By 
European Respiratory Society
Print ISSN 
0903-1936
Online ISSN 
1399-3003
History 
  • Received August 27, 2012
  • Accepted October 5, 2012
  • Published online June 30, 2013.

Article Versions

  • previous version (October 25, 2012 - 14:24).
  • You are viewing the most recent version of this article.
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©ERS 2013

Author Information

  1. Dennis Falzon1,
  2. Neel Gandhi2,
  3. Giovanni B. Migliori3,
  4. Giovanni Sotgiu4,
  5. Helen S. Cox5,
  6. Timothy H. Holtz6,
  7. Maria-Graciela Hollm-Delgado7,
  8. Salmaan Keshavjee8,
  9. Kathryn DeRiemer9,
  10. Rosella Centis3,
  11. Lia D'Ambrosio3,
  12. Christoph G. Lange10,
  13. Melissa Bauer7,11 and
  14. Dick Menzies7⇑
  15. on behalf of the Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB12
  1. 1Stop TB Dept, World Health Organization, Geneva, Switzerland
  2. 2Divisions of General Internal Medicine, Infectious Diseases and Epidemiology, Albert Einstein College of Medicine, New York, NY
  3. 8Dept of Global Health and Social Medicine, Harvard Medical School, Boston, MA
  4. 9School of Medicine, University of California Davis, Davis, CA, USA
  5. 3World Health Organization Collaborating Centre for Tuberculosis and Lung Diseases, Fondazione S. Maugeri, Care and Research Institute, Tradate
  6. 4Dept of Biomedical Sciences, University of Sassari, Sassari, Italy
  7. 5Médecins Sans Frontières, Cape Town, South Africa
  8. 6US Centers for Disease Control and Prevention, HIV/STD Research Program, Bangkok, Thailand
  9. 10Clinical Infectious Diseases, Tuberculosis Center Borstel, Borstel, Germany
  10. 11Dept of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC
  11. 7Montreal Chest Institute, McGill University, Montreal, QC, Canada
  12. 12A full list of the Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB members and their affiliations can be found in the Acknowledgements
  1. D. Menzies, Montréal Chest Institute, 3650 St Urbain St., Montréal, PQ, H2X 2P4, Canada. E-mail: Dick.Menzies{at}McGill.ca
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Resistance to fluoroquinolones and second-line injectable drugs: impact on multidrug-resistant TB outcomes
Dennis Falzon, Neel Gandhi, Giovanni B. Migliori, Giovanni Sotgiu, Helen S. Cox, Timothy H. Holtz, Maria-Graciela Hollm-Delgado, Salmaan Keshavjee, Kathryn DeRiemer, Rosella Centis, Lia D'Ambrosio, Christoph G. Lange, Melissa Bauer, Dick Menzies
European Respiratory Journal Jul 2013, 42 (1) 156-168; DOI: 10.1183/09031936.00134712

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Resistance to fluoroquinolones and second-line injectable drugs: impact on multidrug-resistant TB outcomes
Dennis Falzon, Neel Gandhi, Giovanni B. Migliori, Giovanni Sotgiu, Helen S. Cox, Timothy H. Holtz, Maria-Graciela Hollm-Delgado, Salmaan Keshavjee, Kathryn DeRiemer, Rosella Centis, Lia D'Ambrosio, Christoph G. Lange, Melissa Bauer, Dick Menzies
European Respiratory Journal Jul 2013, 42 (1) 156-168; DOI: 10.1183/09031936.00134712
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