Table of Contents

Original Article

• Epidemiology

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    Hyperhomocysteinaemia predicts the decline in pulmonary function in healthy male smokers

    Keiko Nunomiya, Yoko Shibata, Shuichi Abe, Sumito Inoue, Akira Igarashi, Keiko Yamauchi, Yasuko Aida, Hiroyuki Kishi, Masamichi Sato, Tetsu Watanabe, Tsuneo Konta, Yoshiyuki Ueno, Takeo Kato, Hidetoshi Yamashita, Takamasa Kayama, Isao Kubota

    European Respiratory Journal 42 (1) 18-27; DOI: 10.1183/09031936.00066212 Published 30 June 2013

    • Supplementary material
    • Supplementary material

• COPD

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    Increased phosphorylated p38 mitogen-activated protein kinase in COPD lungs

    Kate Gaffey, Sophie Reynolds, Jonathan Plumb, Manminder Kaur, Dave Singh

    European Respiratory Journal 42 (1) 28-41; DOI: 10.1183/09031936.00170711 Published 30 June 2013

    • Disclosures
    • Supplementary material
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    Bronchiolar epithelial catalase is diminished in smokers with mild COPD

    Tomoko Betsuyaku, Satoshi Fuke, Takashi Inomata, Kichizo Kaga, Toshiaki Morikawa, Nao Odajima, Tracy Adair-Kirk, Masaharu Nishimura

    European Respiratory Journal 42 (1) 42-53; DOI: 10.1183/09031936.00058912 Published 30 June 2013

    • Supplementary material
    • Supplementary material

• α1-antitrypsin deficiency

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    Clinical phenotypes of Italian and Spanish patients with α₁-antitrypsin deficiency

    Barbara Piras, Ilaria Ferrarotti, Beatriz Lara, Maria Teresa Martinez, Ana Bustamante, Stefania Ottaviani, Pietro Pirina, Maurizio Luisetti, Marc Miravitlles

    European Respiratory Journal 42 (1) 54-64; DOI: 10.1183/09031936.00104712 Published 30 June 2013

    • CME questions
    • Supplementary material
    • Disclosures
    • Supplementary material

• Asthma

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    Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics

    Christina Orsmark-Pietras, Anna James, Jon R. Konradsen, Björn Nordlund, Cilla Söderhäll, Ville Pulkkinen, Christophe Pedroletti, Kameran Daham, Maciek Kupczyk, Barbro Dahlén, Juha Kere, Sven-Erik Dahlén, Gunilla Hedlin, Erik Melén

    European Respiratory Journal 42 (1) 65-78; DOI: 10.1183/09031936.00077712 Published 30 June 2013

    • Supplementary material
    • Supplementary material
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    The use of inhaled corticosteroids and the risk of adrenal insufficiency

    Francesco Lapi, Abbas Kezouh, Samy Suissa, Pierre Ernst

    European Respiratory Journal 42 (1) 79-86; DOI: 10.1183/09031936.00080912 Published 30 June 2013

    • Disclosures
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    Barrier responses of human bronchial epithelial cells to grass pollen exposure

    Cornelia Blume, Emily J. Swindle, Patrick Dennison, Nivenka P. Jayasekera, Sarah Dudley, Phillip Monk, Heidrun Behrendt, Carsten B. Schmidt-Weber, Stephen T. Holgate, Peter H. Howarth, Claudia Traidl-Hoffmann, Donna E. Davies

    European Respiratory Journal 42 (1) 87-97; DOI: 10.1183/09031936.00075612 Published 30 June 2013

    • Supplementary material

• Paediatric Asthma

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    Exhaled volatile organic compounds predict exacerbations of childhood asthma in a 1-year prospective study

    Charlotte M. Robroeks, Joep J. van Berkel, Quirijn Jöbsis, Frederik-Jan van Schooten, Jan W. Dallinga, Emiel F. Wouters, Edward Dompeling

    European Respiratory Journal 42 (1) 98-106; DOI: 10.1183/09031936.00010712 Published 30 June 2013
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    Reduced neonatal lung function and wheezing illnesses during the first 5 years of life

    Anne C. van der Gugten, Cuno S.P.M. Uiterwaal, Nienke van Putte-Katier, Marije Koopman, Theo J.M. Verheij, Cornelis K. van der Ent

    European Respiratory Journal 42 (1) 107-115; DOI: 10.1183/09031936.00214711 Published 30 June 2013

    • Disclosures
    • Supplementary material

• Paediatric Lung Function

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    Repeatability and bronchodilator reversibility of lung function in young children

    Samatha Sonnappa, Cristina M. Bastardo, Angie Wade, Andrew Bush, Janet Stocks, Paul Aurora

    European Respiratory Journal 42 (1) 116-124; DOI: 10.1183/09031936.00076012 Published 30 June 2013

    • Supplementary material
    • Supplementary material

• Pulmonary Vascular Disease

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    Noninvasive cardiac output measurements in patients with pulmonary hypertension

    Jonathan D. Rich, Stephen L. Archer, Stuart Rich

    European Respiratory Journal 42 (1) 125-133; DOI: 10.1183/09031936.00102212 Published 30 June 2013
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    Outpatient versus inpatient treatment in patients with pulmonary embolism: a meta-analysis

    Wendy Zondag, Judith Kooiman, Frederikus A. Klok, Olaf M. Dekkers, Menno V. Huisman

    European Respiratory Journal 42 (1) 134-144; DOI: 10.1183/09031936.00093712 Published 30 June 2013

    • Supplementary material
    • Supplementary material

• Sleep-related Disorders

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    Detection of obstructive sleep apnoea by an electronic nose

    Timm Greulich, Akira Hattesohl, Antje Grabisch, Janine Koepke, Severin Schmid, Sarah Noeske, Christoph Nell, Marion Wencker, Rudolf A. Jörres, Claus Franz Vogelmeier, Ulrich Köhler, Andreas Rembert Koczulla

    European Respiratory Journal 42 (1) 145-155; DOI: 10.1183/09031936.00091712 Published 30 June 2013

    • Disclosures
    • Supplementary material

• Tuberculosis

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    Resistance to fluoroquinolones and second-line injectable drugs: impact on multidrug-resistant TB outcomes

    Dennis Falzon, Neel Gandhi, Giovanni B. Migliori, Giovanni Sotgiu, Helen S. Cox, Timothy H. Holtz, Maria-Graciela Hollm-Delgado, Salmaan Keshavjee, Kathryn DeRiemer, Rosella Centis, Lia D'Ambrosio, Christoph G. Lange, Melissa Bauer, Dick Menzies on behalf of the Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB

    European Respiratory Journal 42 (1) 156-168; DOI: 10.1183/09031936.00134712 Published 30 June 2013

    • Supplementary material
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    Drug resistance beyond extensively drug-resistant tuberculosis: individual patient data meta-analysis

    Giovanni Battista Migliori, Giovanni Sotgiu, Neel R. Gandhi, Dennis Falzon, Kathryn DeRiemer, Rosella Centis, Maria-Graciela Hollm-Delgado, Domingo Palmero, Carlos Pérez-Guzmán, Mario H. Vargas, Lia D'Ambrosio, Antonio Spanevello, Melissa Bauer, Edward D. Chan, H. Simon Schaaf, Salmaan Keshavjee, Timothy H. Holtz, Dick Menzies, The Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB

    European Respiratory Journal 42 (1) 169-179; DOI: 10.1183/09031936.00136312 Published 30 June 2013

• Community-Acquired Pneumonia

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    Obesity is associated with improved survival in community-acquired pneumonia

    Anika Singanayagam, Aran Singanayagam, James D. Chalmers

    European Respiratory Journal 42 (1) 180-187; DOI: 10.1183/09031936.00115312 Published 30 June 2013

• Acute Lung Injury

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    Intrabronchial activated protein C enhances lipopolysaccharide-induced pulmonary responses

    Liesbeth M. Kager, J. Daan de Boer, Paul Bresser, Jaring S. van der Zee, Sacha Zeerleder, Joost C.M. Meijers, Cornelis van 't Veer, Tom van der Poll

    European Respiratory Journal 42 (1) 188-197; DOI: 10.1183/09031936.00057112 Published 30 June 2013

    • Supplementary material

• Idiopathic Pulmonary Fibrosis

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    Cell cycle dependence of ACE-2 explains downregulation in idiopathic pulmonary fibrosis

    Bruce D. Uhal, MyTrang Dang, Vinh Dang, Roger Llatos, Esteban Cano, Amal Abdul-Hafez, Jonathan Markey, Christopher C. Piasecki, Maria Molina-Molina

    European Respiratory Journal 42 (1) 198-210; DOI: 10.1183/09031936.00015612 Published 30 June 2013

• Interstitial Lung Disease

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    Respiratory muscle function in interstitial lung disease

    Stephan Walterspacher, Daniel Schlager, David J. Walker, Joachim Müller-Quernheim, Wolfram Windisch, Hans-Joachim Kabitz

    European Respiratory Journal 42 (1) 211-219; DOI: 10.1183/09031936.00109512 Published 30 June 2013

• Lung Cancer

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    Bronchial colonisation in patients with lung cancer: a prospective study

    Sophie Laroumagne, Benoît Lepage, Christophe Hermant, Gavin Plat, Michael Phelippeau, Laurence Bigay-Game, Stéphanie Lozano, Nicolas Guibert, Christine Segonds, Valérie Mallard, Nathalie Augustin, Alain Didier, Julien Mazieres

    European Respiratory Journal 42 (1) 220-229; DOI: 10.1183/09031936.00062212 Published 30 June 2013