To the Editor:
We report a patient with a pulmonary squamous dysplastic lesion that appears as pure ground-glass opacity (GGO) on computed tomography (CT).
An ill-defined, 15-mm nodular lesion in the left lower lung was noted on a radiograph during an annual health check-up of a 61-year-old female who had never smoked. A physical examination and laboratory study results were unremarkable. Chest CT demonstrated a well-demarcated pure GGO nodule in the inferior lobe of the left lung. The nodule, measuring 15×13 mm, was located in the anteromedial basal segment (S8) (fig. 1a). A positron emission tomography scan showed no accumulation of radioactivity in the lesion. The patient underwent S8 segmentectomy of the left lung with lymph node sampling.
a) Chest computed tomography (CT) shows a well-demarcated pure ground-glass opacity nodule (arrowhead), measuring 15×13 mm, in the anteromedial basal segment of the left lung. b) Polygonal cells are present along the alveolar walls, but the alveolar structure is preserved (haematoxylin and eosin; scale bar=100 μm). c) Immunohistochemical staining for p63. The atypical cells were positive for p63. d) Immunohistochemical staining for TTF-1. The atypical cells were …
