Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions

Characteristics and outcomes of hospitalizations for acute exacerbation of chronic obstructive pulmonary disease (AECOPD)

Tyler Knight, Xiao Xu, Rebecca Baik, Xiao Tu, Joseph Parker, Nestor Molfino
European Respiratory Journal 2012 40: P4751; DOI:
Tyler Knight
1Health Economics and Outcomes Research, Covance Market Access Services, Inc., Gaithersburg, MD, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xiao Xu
2Clinical Development, MedImmune, LLC, Gaithersburg, MD, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rebecca Baik
1Health Economics and Outcomes Research, Covance Market Access Services, Inc., Gaithersburg, MD, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xiao Tu
2Clinical Development, MedImmune, LLC, Gaithersburg, MD, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joseph Parker
2Clinical Development, MedImmune, LLC, Gaithersburg, MD, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nestor Molfino
2Clinical Development, MedImmune, LLC, Gaithersburg, MD, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • PDF
Loading

Abstract

RATIONALE: Up to 25% of AECOPD events require hospitalization. However, data on AECOPD hospitalizations, including seasonal patterns, health resource use (HRU) and post-discharge readmission is limited. This study describes the characteristics and outcomes of AECOPD treated in US hospitals.

METHODS: A retrospective study of COPD patients treated in 376 US hospitals for AECOPD from 2007-2010 was conducted with the Premier Perspective® database. All AECOPD hospitalizations for COPD patients aged 40-85 years were identified. Characteristics of AECOPD hospitalizations (including seasonal patterns, length of stay [LOS], proportions admitted to ICU and treated with ventilator, and in-hospital mortality) and 30- to 90-day post-discharge readmission were summarized.

RESULTS: Of 285,752 AECOPD hospitalizations identified, most were found in the winter season (December-March, range 9.2-10.3%), peaking in March (10.3%); while the fewest were found in the summer season (June-September, range 6.5-7.5%), dipping in August (6.5%). Median LOS was 4 days; 20.5% included ICU admission and 12.9% required ventilator use. In-hospital mortality was 3.3% overall; 10.6% and 1.5% with and without an ICU stay, respectively; and 13.9% and 1.8% with and without ventilator use, respectively. Within 30, 60 and 90 days after discharge, readmission rates to the same hospital were 10.4%, 14.6% and 17.4%, respectively.

CONCLUSONS: AECOPD-related hospitalizations are most prevalent from December to March and represent substantial healthcare burden by high readmission rates, substantial HRU, and resulting mortality. Early preventive treatment may reduce disease burden of AECOPD events.

  • COPD - exacerbations
  • Epidemiology
  • Intensive care
  • © 2012 ERS
Previous
Back to top
Vol 40 Issue Suppl 56 Table of Contents
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Characteristics and outcomes of hospitalizations for acute exacerbation of chronic obstructive pulmonary disease (AECOPD)
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Characteristics and outcomes of hospitalizations for acute exacerbation of chronic obstructive pulmonary disease (AECOPD)
Tyler Knight, Xiao Xu, Rebecca Baik, Xiao Tu, Joseph Parker, Nestor Molfino
European Respiratory Journal Sep 2012, 40 (Suppl 56) P4751;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Characteristics and outcomes of hospitalizations for acute exacerbation of chronic obstructive pulmonary disease (AECOPD)
Tyler Knight, Xiao Xu, Rebecca Baik, Xiao Tu, Joseph Parker, Nestor Molfino
European Respiratory Journal Sep 2012, 40 (Suppl 56) P4751;
del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo
Full Text (PDF)

Jump To

  • Article
  • Info & Metrics
  • PDF
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

  • Exposure to traffic pollution is related to daytime sleepiness and habitual snoring: Results from the RHINE study
  • Risk of cardiovascular comorbidities in patients with idiopathic pulmonary fibrosis: Analysis of Medicare data
  • Traffic related air pollution and transplant failure
Show more 6.1 Epidemiology

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Reviewers
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Publication ethics and malpractice
  • Submit a manuscript

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2022 by the European Respiratory Society