Abstract
Background/Aim: Diabetes Mellitus (DM) is associated with impairment of cardiorespiratory fitness and pulmonary function; increasing evidences have suggested that comorbidities and systemic inflammation may be involved. The objective of this study was evaluate changes in metabolic variables, C-reactive protein (CRP) levels, cardiorespiratory fitness and pulmonary function in DM patients compared with healthy subjects. Methods: 19 men with diabetes (49±2 years) and 19 healthy control subjects (51±1 years) were studied. All subjects performed a spirometry and an incremental cardiopulmonary exercise test on a cycloergometer with electromagnetic breaking (workload increases, range 13-22W/min). Cardiopulmonary data were continuously collected with a metabolic unit. Heart rate (HR) was continuously monitored. Results: are presented in table 1.
Conclusion: The cardiorespiratory fitness is reduced in patients with diabetes but the spirometric values are preserved, and the CRP did not differ of the control subjects.
Financial support: Capes, FAPESP.
- © 2012 ERS