Abstract
AIM: To analyze risk factors for mortality due to lung cancer before 1st and 3rd month after diagnosis.
METHODS: Revision of all the patients with lung cancer diagnosis in 2 years. Analysis of:demographic variables,smoking status,hitologycal subtipe,staging,ECOG,blood analysis,treatments,cause of death.Univariant and multivariant analysis (Cox regression).
RESULTS: 270 cases, characteristics shown in table 1.In table 2, multivariant analysis.AUC of 0,952 in the 1st month, 0,874 for the 3rd. Among 41 patients who died during the 1st month, 9 (22%) recieved palliative treatment (6 Radiotherapy [RT], 3 Chemotherapy [QT]). As death causes: infectious complications in 8 cases (3 QT), respiratory insufficiency 16 cases, rest: tumoral progression and general worsening.
CONCLUSIONS: High percentage of patients die before the 1st month (15%) and 3rd month (29%) after diagnosis. ECOG >2 points,the most impacting factor for early mortality.Other factors: IV TNM stage, low haemoglobin, adenocarcinoma or small-cell histological subtipe (1st month mortality) and a high CA125 level (3rd month mortality).Respiratory insuffiency and infectious complications, the most frecuent death causes apart from tumoral progression.
- © 2012 ERS
