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Proportion of adenocarcinomas of the lung rise from 22 to 42% in a London hospital 2000-2009

Katie Ward, Deepak Rao, Nadeem Maddekar, Katie Hurt, Itziar Atucha, Jane Kelly, Sabine Pomplun, Surinder Birring, Richard D. Barker
European Respiratory Journal 2012 40: P3129; DOI:
Katie Ward
1Department of Respiratory Medicine, King's College Hospital, Denmark Hill, London, United Kingdom
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Deepak Rao
1Department of Respiratory Medicine, King's College Hospital, Denmark Hill, London, United Kingdom
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Nadeem Maddekar
1Department of Respiratory Medicine, King's College Hospital, Denmark Hill, London, United Kingdom
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Katie Hurt
1Department of Respiratory Medicine, King's College Hospital, Denmark Hill, London, United Kingdom
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Itziar Atucha
2Department of Medical Oncology, King's College Hospital, Denmark Hill, London, United Kingdom
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Jane Kelly
2Department of Medical Oncology, King's College Hospital, Denmark Hill, London, United Kingdom
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Sabine Pomplun
3Department of Histopathology, King's College Hospital, Denmark Hill, London, United Kingdom
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Surinder Birring
1Department of Respiratory Medicine, King's College Hospital, Denmark Hill, London, United Kingdom
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Richard D. Barker
1Department of Respiratory Medicine, King's College Hospital, Denmark Hill, London, United Kingdom
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Abstract

Background

The proportion of lung cancers that are adenocarcinomas(ACs) is reported to be increasing in Europe. In 2006-2008 the proportion of UK lung cancers typed as AC was 26%.1 Incidence of lung cancer in females has recently stabilised in the UK.1 Knowledge of local case mix is essential for service planning.

Methods

King's College Hospital, London, UK, has a multiethnic, deprived population of 250 000. Since 1999, all lung cancers have been discussed at a multidisciplinary(MDT) meeting and recorded on a database. Data for histologically confirmed cases of primary lung cancer diagnosed over the period 2000-2009 were studied and stratified into 2-year epochs by date the patient was first seen. The Chi square for trend test was used to examine changes in proportions of cases in i)females versus males; ii)ACs and iii)SCCs versus all other tissue types.

Results

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Table 1 Lung Cancer Cases 2000-9

Conclusion

The trend for increasing proportion of ACs (and decreasing SCCs) was highly significant; the proportion of ACs in our cohort since 2006 is greater than the latest UK figure and numbers of ACs do not appear to have stabilised.1 The proportion of female cases is in line with UK data and is not significantly changing.

Reference

1. Lung Cancer. NICE clinical guideline 121. Issue date: April 2011. National Institute for Health and Clinical Excellence, UK.

  • Lung cancer / Oncology
  • Epidemiology
  • © 2012 ERS
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Proportion of adenocarcinomas of the lung rise from 22 to 42% in a London hospital 2000-2009
Katie Ward, Deepak Rao, Nadeem Maddekar, Katie Hurt, Itziar Atucha, Jane Kelly, Sabine Pomplun, Surinder Birring, Richard D. Barker
European Respiratory Journal Sep 2012, 40 (Suppl 56) P3129;

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Proportion of adenocarcinomas of the lung rise from 22 to 42% in a London hospital 2000-2009
Katie Ward, Deepak Rao, Nadeem Maddekar, Katie Hurt, Itziar Atucha, Jane Kelly, Sabine Pomplun, Surinder Birring, Richard D. Barker
European Respiratory Journal Sep 2012, 40 (Suppl 56) P3129;
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