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Comparison between presence of respiratory symptoms and peak expiratory flow (PEF) values <80% predicted as screening tools for obstructive airways diseases (OAD)

Monica Barne, Komalkirti Apte, Sushmeeta Chhowala, Basant Pachisia, Bill Brashier, Sapna Madas, Jaideep Gogtay, Sundeep Salvi
European Respiratory Journal 2011 38: p917; DOI:
Monica Barne
1Academics, Chest Research Foundation, Pune, Maharashtra, India
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Komalkirti Apte
1Academics, Chest Research Foundation, Pune, Maharashtra, India
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Sushmeeta Chhowala
2Medical Services, Cipla Limited, Mumbai, Maharashtra, India
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Basant Pachisia
2Medical Services, Cipla Limited, Mumbai, Maharashtra, India
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Bill Brashier
1Academics, Chest Research Foundation, Pune, Maharashtra, India
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Sapna Madas
1Academics, Chest Research Foundation, Pune, Maharashtra, India
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Jaideep Gogtay
2Medical Services, Cipla Limited, Mumbai, Maharashtra, India
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Sundeep Salvi
1Academics, Chest Research Foundation, Pune, Maharashtra, India
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Abstract

When screening large populations for OADs, it is not known whether respiratory symptoms or PEF is a better predictor.

Aim: To compare predictive values of presence of respiratory symptoms vs PEF values < 80% predicted for detecting OADs.

Methods: 7154 employees from 24 bus depots and 7 cities and towns of Andhra Pradesh State in India were administered a respiratory health questionnaire and performed peak flow metry using an EU scale Peak Flow Meter (Breathometer, Cipla Ltd. India). Subjects with presence of at least one respiratory symptom and/or PEF values <80% predicted underwent Spirometry according to ATS/ERS standards. OAD was defined as FEV1/FVC <70%, small airways obstruction (SAO) as FEF25-75%<65% of predicted.

Results: Of the 3348 subjects who performed spirometry, 1433 had PEF <80% predicted (Group A), 746 had at least one respiratory symptom but PEF >80% predicted (Group B) and 1169 had both PEF <80% predicted and presence of at least one respiratory symptom (Group C). The prevalence of OAD was 8.9%, 4.1% and 10.5% in Groups A, B and C respectively while the prevalence of SAO was 49%, 27.5% and 46.6% respectively. Use of PEF <80% predicted was a significantly better predictor of OAD (Δ 4.8%; p=0.01) and SAO (Δ 21.5%; p<0.0001) than the presence of respiratory symptoms.

Conclusion: PEF values <80% predicted is a better predictor of OAD and SAO than presence of respiratory symptoms. We recommend use of PFM as a screening tool for OAD in large epidemiological studies.

  • © 2011 ERS
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Comparison between presence of respiratory symptoms and peak expiratory flow (PEF) values <80% predicted as screening tools for obstructive airways diseases (OAD)
Monica Barne, Komalkirti Apte, Sushmeeta Chhowala, Basant Pachisia, Bill Brashier, Sapna Madas, Jaideep Gogtay, Sundeep Salvi
European Respiratory Journal Sep 2011, 38 (Suppl 55) p917;

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Comparison between presence of respiratory symptoms and peak expiratory flow (PEF) values <80% predicted as screening tools for obstructive airways diseases (OAD)
Monica Barne, Komalkirti Apte, Sushmeeta Chhowala, Basant Pachisia, Bill Brashier, Sapna Madas, Jaideep Gogtay, Sundeep Salvi
European Respiratory Journal Sep 2011, 38 (Suppl 55) p917;
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