Abstract
PTE should be evaluated with its clinical, radiological and laboratory findings in order to diagnose. Our aim was to determine the relationship between PESI, cardiac biomarkers and CT findings.
75 cases were diagnosed as acute PTE between September 2009-December 2010. Cases were grouped as nonmassive (group 1: 35), submassive (group 2: 27), massive (group 3: 13) PTE. Three groups were compared in term of PESI, cardiac biomarkers, CT findings (RV/LV ratio-pulmonary vascular obstruction score (PVOS))
Mean age was 58,8 (29-94). PESI (mean±SD) was 78,17±27,66 in group 1, 102,7±34,4 in group 2, 139,9±36,25 in group 3 (p< 0,05). 71,4% of patients in group 1 were classified into PESI class 1-2 wheras 100% of patients in group 3 were classified into PESI class 3-5 (p<0,001). D-dimer (mean±SD/(μg/dl)) was 2998,48±1821,86 in group 1, 3976,88±1873,53 in group 2, 4600,38±2112,28 in group 3 (p< 0,05). ProBNP (mean±SD/(pg/ml))was 137,5±22 in group 1, 3904±1399,25 in group 2, 7901±6689 in group 3 (p<0,05). RV/LV ratio (mean±SD) was 0,85±0,12 in group 1, 1,13±0,30 in group 2, 1,40±0,5 in group 3 (p<0,001). PVOS (mean±SD/(%)) was 18±11 in group 1, 33±16 in group 2, 40±7,7 in group 3 (p< 0,001). PVOS was smaller than 30% in 82,9% of group 1 cases wheras it was higher in 92.3% of group 3 cases (p<0,001). There was a weak positive correlation between PESI and D-dimer (p<0,05), RV/LV (p<0,001), PVOS (p<0,001). A strong positive correlation was found between PESI and pro-BNP (p<0,001).PESI has a significant correlation with CT findings and cardiac biomarkers which are D-Dimer and pro-BNP.
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