Abstract
The aim of this study was to define the clinic and the pulmonary function (PFT) in patients with COPD at the remote period after low-dose ionizing radiation exposure and inhalation of radionuclides emergency descent.
Methods: Group1-57 COPD cleanup workers (individual documented dose of irradiation: 0,01 to 0,5 sZv) exposed to external and internal irradiation (mean age 62,1±1,4 yrs), group2 - 20 COPD patients who were not exposed to radiation (mean age 63,2±2,9 yrs). Clinical examination included-questioning, physical examination, MRC scale, BODE index. PFT was measured using spirometry, bodypletismography and DLCO.
Results: It was found out the significant reduction of lung capacity, a clear violation of the ratio of lung volume, due to certain growth of residual volume and total lung capacity, and reduction of diffuse capasity in a group of clean-up workers COPD patients in compareson with nosological control.Complaints of breathlessness varying degrees of intensity significantly more often expressed by patients with COPD who suffered from Chernobyl compared with control group.
Conclusion: Analysis pathognomonic symptoms for bronchopulmonary disease showed the presence of cough, sputum selection, shortness of breath, in most patients, but complaints of breathlessness varying degrees of intensity significantly more often expressed by patients with COPD who suffered from Chernobyl compared with control group, indicating worse quality of life. Also we indicate the presence of distinct pulmonary hyperinflation, emphysema, and diffuse lung function in a group 1 compared with control.
- © 2011 ERS
