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Primary posterior mediastinum epithelioid angiosarcoma complicated with pulmonary thromboembolism: A case report

Yiliang Su, Beilan Gao, Jinming Liu, Huikang Xie
European Respiratory Journal 2011 38: p2821; DOI:
Yiliang Su
1Respiratory Medicine, Shanghai Pulmonary Hospital, TongJi University School of Medicine, Shanghai, China
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Beilan Gao
1Respiratory Medicine, Shanghai Pulmonary Hospital, TongJi University School of Medicine, Shanghai, China
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Jinming Liu
1Respiratory Medicine, Shanghai Pulmonary Hospital, TongJi University School of Medicine, Shanghai, China
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Huikang Xie
2Pathology, Shanghai Pulmonary Hospital, TongJi University School of Medicine, Shanghai, China
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Abstract

Epithelioid angiosarcoma is a rare subtype of angiosarcoma. We find that no case of primary posterior mediastinum epithelioid angiosarcoma has been reported till now through review of literature. We reported the first case of primary posterior mediastinum epithelioid angiosarcoma complicated with pulmonary thromboembolism. A 77-year-old man was hospitalized with cough and repeated haemoptysis for almost one month. A CT pulmonary angiograpy revealed posterior mediastinal mass and a filling defect in lateral-posterior basal pulmonary artery.

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Figure 1

The patient underwent posterior mediastinum tylectomy, and the histopathological examination results revealed an epitheliod angiosarcoma (figure 2A). Immunohistochemical studies were positive for CD31 (figure 2B) and Factor VIII (figure 2C) and negative for CD34 (figure 2D).

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Figure 2

Though our patient endured tylectomy, he died within 6 months from presentation of cough and haemoptysis.

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Primary posterior mediastinum epithelioid angiosarcoma complicated with pulmonary thromboembolism: A case report
Yiliang Su, Beilan Gao, Jinming Liu, Huikang Xie
European Respiratory Journal Sep 2011, 38 (Suppl 55) p2821;

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Primary posterior mediastinum epithelioid angiosarcoma complicated with pulmonary thromboembolism: A case report
Yiliang Su, Beilan Gao, Jinming Liu, Huikang Xie
European Respiratory Journal Sep 2011, 38 (Suppl 55) p2821;
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