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Study of the lung cancer patients on hemodialysis (HD) in Japan

Ryo Matsunuma, Yoshihiro Ohkuni, Akina Komatsu, Kei Nakashima, Nobuhiro Asai, Hideki Makino, Norihiro Kaneko
European Respiratory Journal 2011 38: p2771; DOI:
Ryo Matsunuma
The Department of Respiratory Medicine, Kameda Medical Center, 929 Higashi-Cho, Chiba, Japan
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Yoshihiro Ohkuni
The Department of Respiratory Medicine, Kameda Medical Center, 929 Higashi-Cho, Chiba, Japan
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Akina Komatsu
The Department of Respiratory Medicine, Kameda Medical Center, 929 Higashi-Cho, Chiba, Japan
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Kei Nakashima
The Department of Respiratory Medicine, Kameda Medical Center, 929 Higashi-Cho, Chiba, Japan
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Nobuhiro Asai
The Department of Respiratory Medicine, Kameda Medical Center, 929 Higashi-Cho, Chiba, Japan
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Hideki Makino
The Department of Respiratory Medicine, Kameda Medical Center, 929 Higashi-Cho, Chiba, Japan
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Norihiro Kaneko
The Department of Respiratory Medicine, Kameda Medical Center, 929 Higashi-Cho, Chiba, Japan
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Abstract

Introduction: Early stage lung cancer in patients with end-stage renal disease are often detected by routine chest radiography on hemodialysis (HD) filtration. It is general that standard treatment for hemodialysis patients with lung cancer are not performed because guideline for lung cancer in HD patients is not established yet. Thus, clinicians have difficulty in treating HD patients even though early stage lung cancer is detected.

Method: We retrospectively analyzed 17 HD patients with lung cancer between April 2004 and September 2010. Patients' characteristics, histology and stage of lung cancer, treatment and outcome were evaluated.

Results: A total 17 patients (13 male, 4 female) were eligible in this study. The median age was 72 years (range 54-90). Eleven patients of non-small cell lung cancer (NSCLC) and 1 small cell lung cancer (SCLC) had histological or cytological confirmation and 5 were unknown. They consist of 3 stageI, 1 stageII, 8 stageIII and IV. As for treatment, operation was taken in 3, chemotherapy alone and radiochemotherapy were received in 4 and 1. Nine patients did not receive any treatment since they are too old, had a poor performance status or considered to be intolerable by attending physicians.In terms of chemotherapy, hepatic excretory anti-cancer drugs were used in all the 4 patients. No severe adverse events related-treatment was seen in this study.

Conclusion: Guideline for HD patients with advanced stage lung cancer should be established.

  • © 2011 ERS
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Study of the lung cancer patients on hemodialysis (HD) in Japan
Ryo Matsunuma, Yoshihiro Ohkuni, Akina Komatsu, Kei Nakashima, Nobuhiro Asai, Hideki Makino, Norihiro Kaneko
European Respiratory Journal Sep 2011, 38 (Suppl 55) p2771;

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Study of the lung cancer patients on hemodialysis (HD) in Japan
Ryo Matsunuma, Yoshihiro Ohkuni, Akina Komatsu, Kei Nakashima, Nobuhiro Asai, Hideki Makino, Norihiro Kaneko
European Respiratory Journal Sep 2011, 38 (Suppl 55) p2771;
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