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CT guided biopsy: Predictors of outcome and complication rate

Rahuldeb Sarkar, Amir Baluwala, James Jamieson-Young, Andrew Wight, Elspeth Partridge, Marta Babores
European Respiratory Journal 2011 38: p2762; DOI:
Rahuldeb Sarkar
1Respiratory Medicine, Macclesfield Hospital, Macclesfield, Cheshire, United Kingdom
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Amir Baluwala
1Respiratory Medicine, Macclesfield Hospital, Macclesfield, Cheshire, United Kingdom
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James Jamieson-Young
1Respiratory Medicine, Macclesfield Hospital, Macclesfield, Cheshire, United Kingdom
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Andrew Wight
1Respiratory Medicine, Macclesfield Hospital, Macclesfield, Cheshire, United Kingdom
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Elspeth Partridge
2Radiology, Macclesfield Hospital, Macclesfield, Cheshire, United Kingdom
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Marta Babores
1Respiratory Medicine, Macclesfield Hospital, Macclesfield, Cheshire, United Kingdom
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Abstract

Background: With a drive towards early diagnosis of lung cancer and aim for curative treatment, CT guided biopsy is being used increasingly. While it is a relatively safe procedure, institutions performing this should audit its practice against recommended standards.

Objective: Measuring this procedure's complication rate and positive results to ascertain if there are any predictors for these outcomes.

Method: A retrospective study was undertaken to collect data for all CT guided biopsies done in last 2 years (2009-10) in our hospital.

Result: 66 biopsies were reviewed. Mean (SD) age of patients was 69 (11) years. Conclusive histology was obtained in 38 (56%). Complication rate and the British Thoracic Society (BTS) standards are shown below.

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Table 1

The mean size and depth from chest wall of lesions in patients with and without PTX, hemorrhage and conclusive biopsies are shown in Table 2.

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Table 2

In lesions with a size of >3cm (n=43), 31 (72%) results were conclusive as opposed to 8 (35%) conclusive results in lesions <3cm (n=23). Positive results for lesions at a depth of >1.5 cm (n=13) was 46% while the same for lesions at depth <1.5 cm (n=53) was 61%.

Conclusion: Good pick up rate with complications well within acceptable standards were achieved in our study population. Depth of the lesion correlated well with pneumothorax and hemorrhage while size correlated with pneumothorax. Size was also a good predictors of conclusive biopsies.

  • © 2011 ERS
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CT guided biopsy: Predictors of outcome and complication rate
Rahuldeb Sarkar, Amir Baluwala, James Jamieson-Young, Andrew Wight, Elspeth Partridge, Marta Babores
European Respiratory Journal Sep 2011, 38 (Suppl 55) p2762;

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CT guided biopsy: Predictors of outcome and complication rate
Rahuldeb Sarkar, Amir Baluwala, James Jamieson-Young, Andrew Wight, Elspeth Partridge, Marta Babores
European Respiratory Journal Sep 2011, 38 (Suppl 55) p2762;
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