Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • ERS Guidelines
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • ERS Guidelines
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Subscriptions

Concordance between IGRA and TST in a cohort of health professional trainees from India

Devasahayam J. Christopher, Prince James, Joy Sarojini Michael, Alice Zwerling, Madhukar Pai
European Respiratory Journal 2011 38: p2657; DOI:
Devasahayam J. Christopher
1Pulmonary Medicine, Christian Medical College, Vellore, Tamil Nadu, India
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Prince James
1Pulmonary Medicine, Christian Medical College, Vellore, Tamil Nadu, India
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joy Sarojini Michael
3Microbiology, Christian Medical College, Vellore, Tamil Nadu, India
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alice Zwerling
2Epidemiology, Biostatistics & Occupational Health, McGill University, Montreal, QC, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Madhukar Pai
2Epidemiology, Biostatistics & Occupational Health, McGill University, Montreal, QC, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
Loading

Abstract

Objectives: To estimate the concordance between the Tuberculin skin test (TST) and Quantiferon TB Gold In-tube, (QFT) among health professional trainees at a referral hospital in India, and to evaluate risk factors associated with discordant results.

Methods: From November 2009 to February 2011, students registered in various health professional programs (with the exception of medical and nursing students) were approached to participate. In addition to a questionnaire on TB exposure, participants underwent TST (10 mm cutoff) and the QFT-GIT (0.35 IU/ml cut off).

Results: 164 students completed. Mean age was 21.5 yrs (Range: 17-34), 48.8% were female and 59.15% had BCG scars. Mean time in health care was 11.5 months, and 21.6% recalled direct contact with PTB. Prevalence of LTBI by TST or QFT was 48.2% and 23.2% respectively. Agreement between tests was 71.3% (kappa=0.415). The predominant discordance was TST +/QFT- (43/164, 26.2%). Using multivariate logistic regression we evaluated whether discordant results were associated with any particular risk factors, including: age, sex, education, family income, time in health care setting, days spent in high risk wards, performing high risk procedures, pre-existing medical illness, BCG, and known TB exposure. No factors were associated with discordant results, however, age was associated with concordant positives (OR=1.27, 95%CI: 1.03-1.59), and higher family income was protective (OR=0.67, 95%CI:0.45-0.99).

Conclusions: There was fair to weak agreement between TST and QFT in this population. Concordant positives were associated with older age, and lower family income. Discordant results were not associated with any known risk factors.

  • © 2011 ERS
Previous
Back to top
Vol 38 Issue Suppl 55 Table of Contents
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Concordance between IGRA and TST in a cohort of health professional trainees from India
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Concordance between IGRA and TST in a cohort of health professional trainees from India
Devasahayam J. Christopher, Prince James, Joy Sarojini Michael, Alice Zwerling, Madhukar Pai
European Respiratory Journal Sep 2011, 38 (Suppl 55) p2657;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Concordance between IGRA and TST in a cohort of health professional trainees from India
Devasahayam J. Christopher, Prince James, Joy Sarojini Michael, Alice Zwerling, Madhukar Pai
European Respiratory Journal Sep 2011, 38 (Suppl 55) p2657;
Reddit logo Technorati logo Twitter logo Connotea logo Facebook logo Mendeley logo

Jump To

  • Article
  • Info & Metrics
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

  • Do kinetics of interferon-gamma responses predict TB relapse?
  • Necessity of re-centrifugation of QuantiFERON®-TB Gold In-Tube samples after plasma harvest
  • Accuracy of IFN-γ and IP-10 detection for diagnosis of tuberculosis in children
Show more 280. Risk assessment for tuberculosis

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Publication ethics and malpractice
  • Submit a manuscript

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2023 by the European Respiratory Society