Abstract
During the chronic bronchopulmonary pathology as CNDL on children on background of iodine deficiency diseases, accompanied with the chain of unfavorable event in immune system, metabolic processes which aggravate the clinical course, as well as make ill effects.
Under observation were 68 children with CNDL average age patients 8,4±0,2. Remoteness of diseases 4,71±0,4 years.
At determination of the size of the thyroid gland on US have revealed: hyperplasia of thyroid gland I-degree on 52,3% children with CNDL, on 28,5% II-degree, on 19% are normal size of the organ.
The Analysis have shown that the level of TTG in contents of serum in all patients were higher than checking group (R<0,001). The Level of free triiodothyronine (TTh) and thyroxin (T4) were lower on 77,9%, but on 22,1% examined were normal.
Also contents of cortisol on patients with severe condition were high (144±6,56 mg/ml) as compared with patients in medium condition (89,6±8,3 mg/ml).
For estimation of iodine insufficiency degree we defined the concentration of the iodine in single portion of the urine by photometrical method. On 25% examined, median concentration of the iodine in urine was found the moderate iodine insufficiency degree (20-49 Mκg/l), on 55.8% light degree (50-99 Mκg/l), but on 19% iodine concentration in urine was above 100 Mκr/l. Thus, presence of iodine deficiency diseases in children with CNDL, has a definite significance during and outcome of chronic bronchopulmonary process, which requires additional and regular introduction of iodine-containing preparation and thyroid hormone.
- © 2011 ERS
