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Ambulatory oxygen in interstitial lung disease

D. Visca, A. Montgomery, A. de Lauretis, P. Sestini, H. Soteriou, T.M. Maher, A.U. Wells, E.A. Renzoni
European Respiratory Journal 2011 38: 987-990; DOI: 10.1183/09031936.00190710
D. Visca
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A. Montgomery
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A. de Lauretis
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P. Sestini
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H. Soteriou
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T.M. Maher
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A.U. Wells
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E.A. Renzoni
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  • For correspondence: e.renzoni@imperial.ac.uk
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Tables

  • Table 1– Change in 6-min walk test (6MWT) performance on ambulatory oxygen
    6MWT at baseline6MWT on oxygen#p-value
    In all ILD patients¶
     Distance m255.1±16.8286.0±14.9<0.00001
     Sa,O2 end test %76.3±1.184.7±1.1<0.00001
     Borg scale end test+4.75 (4–5)3.75 (3–4.3)<0.00001
     Heart rate end test120.4±2.0115.9±2.30.03
     Heart rate recovery time s218.5±19.9145.5±10.4<0.00001
     Borg score recovery time s185.3±21.2133.7±12.80.0002
     Sa,O2 recovery time s183.6±20.2102.7±8.5<0.00001
    In patients who completed both 6MWTs without stops§
     Distance m318.9±15.4332.3±15.10.002
     Sa,O2 end test %78.2±1.286.7±1.1<0.00001
     Borg scale end test+4.0 (3–5)3.5 (2.5–4)<0.00001
     Heart rate end test118.6±2.6112.5±3.10.04
     Heart rate recovery time s210.4±27.6132.3±11.90.001
     Borg score recovery time s175.1±29.6116.0±16.10.001
     Sa,O2 recovery time s162.2±24.283.8±8.30.0005
    In patients who stopped at least once during the baseline 6MWTƒ
     Distance m144.2±19.2205.6±21.20.0001
     Sa,O2 end test %73±2.081.3±2.0<0.00001
     Borg scale end test+5 (4–6.7)5 (3.3–6.0)0.02
     Heart rate end test123.5±3.1121.9±3.2ns
     Heart rate recovery time s231.9±27.2167.8±18.50.0007
     Borg score recovery time s203.2±27.4164.5±19.60.07
     Sa,O2 recovery time s220.6±35.3135.7±15.80.004
    In fibrotic IIP patients##
     Distance m272.3±19.8304.7±17.80.0001
     Sa,O2 end test %75.6±1.183.4±1.3<0.00001
     Borg scale end test+4.25 (3–5)3.25±(2.5–4)<0.00001
     Heart rate end test119.6±2.5116.6±3.0ns
     Heart rate recovery time s214.3±25.9138.1±12.40.0003
     Borg score recovery time s167.1±28.2120.7±15.50.008
     Sa,O2 recovery time s177.4±24.2104.0±10.50.0007
    • All values are expressed as mean±se unless stated otherwise. ILD: interstitial lung disease; Sa,O2: arterial oxygen saturation; IIP: idiopathic fibrotic interstitial pneumonia. #: additional or increased; ¶: n=52; +: median (95% CI); §: n=33; ƒ: n=19; ##: n=34.

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Ambulatory oxygen in interstitial lung disease
D. Visca, A. Montgomery, A. de Lauretis, P. Sestini, H. Soteriou, T.M. Maher, A.U. Wells, E.A. Renzoni
European Respiratory Journal Oct 2011, 38 (4) 987-990; DOI: 10.1183/09031936.00190710

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Ambulatory oxygen in interstitial lung disease
D. Visca, A. Montgomery, A. de Lauretis, P. Sestini, H. Soteriou, T.M. Maher, A.U. Wells, E.A. Renzoni
European Respiratory Journal Oct 2011, 38 (4) 987-990; DOI: 10.1183/09031936.00190710
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