Tables
- Table 1– Change in 6-min walk test (6MWT) performance on ambulatory oxygen
6MWT at baseline 6MWT on oxygen# p-value In all ILD patients¶ Distance m 255.1±16.8 286.0±14.9 <0.00001 Sa,O2 end test % 76.3±1.1 84.7±1.1 <0.00001 Borg scale end test+ 4.75 (4–5) 3.75 (3–4.3) <0.00001 Heart rate end test 120.4±2.0 115.9±2.3 0.03 Heart rate recovery time s 218.5±19.9 145.5±10.4 <0.00001 Borg score recovery time s 185.3±21.2 133.7±12.8 0.0002 Sa,O2 recovery time s 183.6±20.2 102.7±8.5 <0.00001 In patients who completed both 6MWTs without stops§ Distance m 318.9±15.4 332.3±15.1 0.002 Sa,O2 end test % 78.2±1.2 86.7±1.1 <0.00001 Borg scale end test+ 4.0 (3–5) 3.5 (2.5–4) <0.00001 Heart rate end test 118.6±2.6 112.5±3.1 0.04 Heart rate recovery time s 210.4±27.6 132.3±11.9 0.001 Borg score recovery time s 175.1±29.6 116.0±16.1 0.001 Sa,O2 recovery time s 162.2±24.2 83.8±8.3 0.0005 In patients who stopped at least once during the baseline 6MWTƒ Distance m 144.2±19.2 205.6±21.2 0.0001 Sa,O2 end test % 73±2.0 81.3±2.0 <0.00001 Borg scale end test+ 5 (4–6.7) 5 (3.3–6.0) 0.02 Heart rate end test 123.5±3.1 121.9±3.2 ns Heart rate recovery time s 231.9±27.2 167.8±18.5 0.0007 Borg score recovery time s 203.2±27.4 164.5±19.6 0.07 Sa,O2 recovery time s 220.6±35.3 135.7±15.8 0.004 In fibrotic IIP patients## Distance m 272.3±19.8 304.7±17.8 0.0001 Sa,O2 end test % 75.6±1.1 83.4±1.3 <0.00001 Borg scale end test+ 4.25 (3–5) 3.25±(2.5–4) <0.00001 Heart rate end test 119.6±2.5 116.6±3.0 ns Heart rate recovery time s 214.3±25.9 138.1±12.4 0.0003 Borg score recovery time s 167.1±28.2 120.7±15.5 0.008 Sa,O2 recovery time s 177.4±24.2 104.0±10.5 0.0007 All values are expressed as mean±se unless stated otherwise. ILD: interstitial lung disease; Sa,O2: arterial oxygen saturation; IIP: idiopathic fibrotic interstitial pneumonia. #: additional or increased; ¶: n=52; +: median (95% CI); §: n=33; ƒ: n=19; ##: n=34.