Figures
- Fig. 1—
Apoptosis measurement of lung adenocarcinoma cells with talc (75 μg·mL−1) at 72 h. G0/G1: 52.56% 5: 11.30%; G2/M: 9.94%; Apoptotic: 26.2%.
- Fig. 2—
Comparison of agents (75 μg·mL−1) on apoptosis of lung adenocarcinoma cells (LAC) and pleural mesothelial cells (PMC) at 72 h. □: talc; ▒: bleomycin; ░: doxycycline; ▪: silicone beads control.
Tables
- Table 1—
Talc and apoptosis of pleural mesothelial cells and lung adenocarcinoma
Agent Apoptosis measurement# Lung adenocarcinoma Pleural mesothelial cells 0 h 24 h 48 h 72 h 0 h 24 h 48 h 72 h Talc 25 μg·mL1 0.2 1.6 6.2 12.0 0.1 0.1 0.3 0.6 50 μg·mL−1 0.2 5.9 9.6 16.0 0.1 0.1 0.1 1.4 75 μg·mL−1 0.2 5.9 16.4 26.2 0.1 0.1 0.2 1.6 Bleomycin 25 μg·mL−1 0.1 0.2 1.5 2.4 0.1 0.1 0.6 2.1 50 μg·mL−1 0.2 0.2 2.2 2.5 0.1 0.1 1.0 2.5 75 μg·mL−1 0.5 0.5 2.3 3.7 0.1 0.3 1.5 3.0 Doxycycline 25 μg·mL−1 0.2 11.2 16.4 23.1 0.1 1.4 9.6 12.6 50 μg·mL−1 0.2 33.1 33.4 46.5 0.1 10.1 14.2 19.2 75 μg·mL−1 0.1 39.4 45.0 71.5 0.6 14.1 17.8 27.6 Silicone beads 25 μg·mL−1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 50 μg·mL−1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.7 75 μg·mL−1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.8 Data are presented as % and represent the median of three independent studies. Experiments were performed in triplicates at each time-point and for each cell line. #: apoptosis of lung cancer cells and pleural mesothelial cells was measured with propidium iodide staining and flow cytometric analysis.
Vol 35 Issue 2
Table of Contents
Selective apoptosis of lung cancer cells with talc
