To the Editors:
We read with interest the recent paper by Restrepo et al. 1 who reported that adding a macrolide to the antibiotic regimen in patients with community-acquired pneumonia (CAP) and severe sepsis resulted in lower mortality. Their data are very promising. However, we have a concern regarding the recommendations to implement macrolides as standard treatment for CAP.
Treatment with macrolides has been shown to have beneficial effects in chronic …