European Respiratory Journal: 32 (5)

01 November 2008; volume 32, issue 5

Editorial

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The secret life of steroids in asthma
P. J. Sterk, C. Y. Yick, A. M. Slats

European Respiratory Journal 32 (5) 1135-1137; DOI: 10.1183/09031936.00135508 Published 31 October 2008
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Genome-wide expression profiling of T-cells in childhood wheeze
A. Bosco, P. G. Holt

European Respiratory Journal 32 (5) 1138-1140; DOI: 10.1183/09031936.00130108 Published 31 October 2008
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Small studies: strengths and limitations
A. Hackshaw

European Respiratory Journal 32 (5) 1141-1143; DOI: 10.1183/09031936.00136408 Published 31 October 2008
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Respiratory education: a dangerous drift away from academia?
M. Polkey, T. Howes, G. Burns, S. G. Spiro

European Respiratory Journal 32 (5) 1144-1145; DOI: 10.1183/09031936.00137008 Published 31 October 2008

Perspective

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Desmosine as a biomarker of elastin degradation in COPD: current status and future directions
M. Luisetti, S. Ma, P. Iadarola, P. J. Stone, S. Viglio, B. Casado, Y. Y. Lin, G. L. Snider, G. M. Turino

European Respiratory Journal 32 (5) 1146-1157; DOI: 10.1183/09031936.00174807 Published 31 October 2008
CME questionnaire

Original Articles: Rapid communication: lung cancer

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Lung cancer gene associated with COPD: triple whammy or possible confounding effect?
R. P. Young, R. J. Hopkins, B. A. Hay, M. J. Epton, P. N. Black, G. D. Gamble

European Respiratory Journal 32 (5) 1158-1164; DOI: 10.1183/09031936.00093908 Published 31 October 2008

Original Articles: Clinical forum: tuberculosis

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GenoType MTBDR assays for the diagnosis of multidrug-resistant tuberculosis: a meta-analysis
D. I. Ling, A. A. Zwerling, M. Pai

European Respiratory Journal 32 (5) 1165-1174; DOI: 10.1183/09031936.00061808 Published 31 October 2008

Original Articles: Bench to bedside: breatheomics

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Metabonomic analysis of exhaled breath condensate in adults by nuclear magnetic resonance spectroscopy
G. de Laurentiis, D. Paris, D. Melck, M. Maniscalco, S. Marsico, G. Corso, A. Motta, M. Sofia

European Respiratory Journal 32 (5) 1175-1183; DOI: 10.1183/09031936.00072408 Published 31 October 2008

Original Articles: Respiratory cell biology

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Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM₁₀
E. Alfaro-Moreno, T. S. Nawrot, B. M. Vanaudenaerde, M. F. Hoylaerts, J. A. Vanoirbeek, B. Nemery, P. H. M. Hoet

European Respiratory Journal 32 (5) 1184-1194; DOI: 10.1183/09031936.00044008 Published 31 October 2008
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Effect of fudosteine on mucin production
C. K. Rhee, C. M. Kang, M. B. You, H. K. Yoon, Y. K. Kim, K. H. Kim, H. S. Moon, S. H. Park, J. S. Song

European Respiratory Journal 32 (5) 1195-1202; DOI: 10.1183/09031936.00018508 Published 31 October 2008

Original Articles: Wheezy infants

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Gene expression in CD4+ T-cells reflects heterogeneity in infant wheezing phenotypes
B. Kapitein, M. O. Hoekstra, E. H. J. Nijhuis, D. J. Hijnen, H. G. M. Arets, J. L. L. Kimpen, E. F. Knol

European Respiratory Journal 32 (5) 1203-1212; DOI: 10.1183/09031936.00020108 Published 31 October 2008

Original Articles: Airway remodelling

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The epidermal growth factor receptor mediates allergic airway remodelling in the rat
M. Tamaoka, M. Hassan, T. McGovern, D. Ramos-Barbón, T. Jo, Y. Yoshizawa, B. Tolloczko, Q. Hamid, J. G. Martin

European Respiratory Journal 32 (5) 1213-1223; DOI: 10.1183/09031936.00166907 Published 31 October 2008

Original Articles: Asthma

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Steroids augment relengthening of contracted airway smooth muscle: potential additional mechanism of benefit in asthma
O. J. Lakser, M. L. Dowell, F. L. Hoyte, B. Chen, T. L. Lavoie, C. Ferreira, L. H. Pinto, N. O. Dulin, P. Kogut, J. Churchill, R. W. Mitchell, J. Solway

European Respiratory Journal 32 (5) 1224-1230; DOI: 10.1183/09031936.00092908 Published 31 October 2008
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The relation between paracetamol use and asthma: a GA²LEN European case–control study
S. Shaheen, J. Potts, L. Gnatiuc, J. Makowska, M. L. Kowalski, G. Joos, T. van Zele, Y. van Durme, I. De Rudder, S. Wöhrl, J. Godnic-Cvar, L. Skadhauge, G. Thomsen, T. Zuberbier, K. C. Bergmann, L. Heinzerling, M. Gjomarkaj, A. Bruno, E. Pace, S. Bonini, W. Fokkens, E. J. M. Weersink, C. Loureiro, A. Todo-Bom, C. M. Villanueva, C. Sanjuas, J-P. Zock, C. Janson, P. Burney

European Respiratory Journal 32 (5) 1231-1236; DOI: 10.1183/09031936.00039208 Published 31 October 2008
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The response to combination therapy treatment regimens in severe/difficult-to-treat asthma
J. D. Campbell, L. Borish, T. Haselkorn, L. Rasouliyan, J. H. Lee, S. E. Wenzel, S. D. Sullivan on behalf of the TENOR Study Group

European Respiratory Journal 32 (5) 1237-1242; DOI: 10.1183/09031936.00112107 Published 31 October 2008

Original Articles: Paediatric asthma and rhinitis

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Role of monocyte chemotactic protein-3 and -4 in children with virus exacerbation of asthma
J. Santiago, J. L. Hernández-Cruz, M. E. Manjarrez-Zavala, R. Montes-Vizuet, D. P. Rosete-Olvera, A. M. Tapia-Díaz, H. Zepeda-Peney, L. M. Terán

European Respiratory Journal 32 (5) 1243-1942; DOI: 10.1183/09031936.00085107 Published 31 October 2008
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International variation in prevalence of rhinitis and its relationship with sensitisation to perennial and seasonal allergens
G. Weinmayr, F. Forastiere, S. K. Weiland, P. Rzehak, T. Abramidze, I. Annesi-Maesano, B. Björkstén, B. Brunekreef, G. Büchele, W. O. C. Cookson, E. von Mutius, R. Pistelli, D. P. Strachan the ISAAC Phase Two Study Group

European Respiratory Journal 32 (5) 1250-1261; DOI: 10.1183/09031936.00157807 Published 31 October 2008
Supplementary methods and statistics

Original Articles: Paediatric lung function

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Reference values for peak flow and FEV₁ variation in healthy schoolchildren using home spirometry
A. F. J. Brouwer, R. J. Roorda, E. J. Duiverman, P. L. P. Brand

European Respiratory Journal 32 (5) 1262-1268; DOI: 10.1183/09031936.00148107 Published 31 October 2008

Original Articles: COPD

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The modified BODE index: validation with mortality in COPD
C. G. Cote, V. M. Pinto-Plata, J. M. Marin, H. Nekach, L. J. Dordelly, B. R. Celli

European Respiratory Journal 32 (5) 1269-1274; DOI: 10.1183/09031936.00138507 Published 31 October 2008
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Effects of hyperinflation on the oxygen pulse as a marker of cardiac performance in COPD
C. Vassaux, L. Torre-Bouscoulet, S. Zeineldine, F. Cortopassi, H. Paz-Díaz, B. R. Celli, V. M. Pinto-Plata

European Respiratory Journal 32 (5) 1275-1282; DOI: 10.1183/09031936.00151707 Published 31 October 2008

Original Articles: Steroids and bacterial infection

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Fluticasone propionate reduces bacterial airway epithelial invasion
M. Barbier, A. Agustí, S. Albertí

European Respiratory Journal 32 (5) 1283-1288; DOI: 10.1183/09031936.00020608 Published 31 October 2008

Original Articles: Pulmonary hypertension

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Inhalation of vasoactive intestinal peptide in pulmonary hypertension
H. H. Leuchte, C. Baezner, R. A. Baumgartner, D. Bevec, G. Bacher, C. Neurohr, J. Behr

European Respiratory Journal 32 (5) 1289-1294; DOI: 10.1183/09031936.00050008 Published 31 October 2008

Original Articles: Environmental exposures

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An epidemic of silicosis among former denim sandblasters
M. Akgun, O. Araz, I. Akkurt, A. Eroglu, F. Alper, L. Saglam, A. Mirici, M. Gorguner, B. Nemery

European Respiratory Journal 32 (5) 1295-1303; DOI: 10.1183/09031936.00093507 Published 31 October 2008

Original Articles: Sleep-disordered breathing

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Heritability of upper airway dimensions derived using acoustic pharyngometry
S. R. Patel, J. M. Frame, E. K. Larkin, S. Redline

European Respiratory Journal 32 (5) 1304-1308; DOI: 10.1183/09031936.00029808 Published 31 October 2008
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Collapsibility of the relaxed pharynx and risk of sleep apnoea
A. Oliven, E. Aspandiarov, I. Gankin, L. Gaitini, N. Tov

European Respiratory Journal 32 (5) 1309-1315; DOI: 10.1183/09031936.00139407 Published 31 October 2008

Original Articles: Genetics of pneumothorax

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Novel mutations in the folliculin gene associated with spontaneous pneumothorax
B. A. Fröhlich, C. Zeitz, G. Mátyás, H. Alkadhi, C. Tuor, W. Berger, E. W. Russi

European Respiratory Journal 32 (5) 1316-1320; DOI: 10.1183/09031936.00132707 Published 31 October 2008

Original Articles: Pleural effusion

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Pleural drainage and pleurodesis: implementation of guidelines in four hospitals
J. A. Burgers, P. W. A. Kunst, M. G. J. Koolen, L. N. A. Willems, J. S. Burgers, M. van den Heuvel

European Respiratory Journal 32 (5) 1321-1327; DOI: 10.1183/09031936.00165607 Published 31 October 2008

Original Articles: Mechanical ventilation

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Impact of home mechanical ventilation on health-related quality of life
W. Windisch on behalf of the quality of life in home mechanical ventilation study group

European Respiratory Journal 32 (5) 1328-1336; DOI: 10.1183/09031936.00066407 Published 31 October 2008

Original Articles: Lung injury

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Effects of edaravone, a free-radical scavenger, on bleomycin-induced lung injury in mice
S. Tajima, M. Bando, Y. Ishii, T. Hosono, H. Yamasawa, S. Ohno, T. Takada, E. Suzuki, F. Gejyo, Y. Sugiyama

European Respiratory Journal 32 (5) 1337-1343; DOI: 10.1183/09031936.00164407 Published 31 October 2008
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Peroxisome proliferator-activated receptor-α reduces inflammation and vascular leakage in a murine model of acute lung injury
M. B. Schaefer, A. Pose, J. Ott, M. Hecker, A. Behnk, R. Schulz, N. Weissmann, A. Günther, W. Seeger, K. Mayer

European Respiratory Journal 32 (5) 1344-1353; DOI: 10.1183/09031936.00035808 Published 31 October 2008

Review

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Protozoa in respiratory pathology: a review
R. Martínez-Girón, J. G. Esteban, A. Ribas, L. Doganci

European Respiratory Journal 32 (5) 1354-1370; DOI: 10.1183/09031936.00022008 Published 31 October 2008

Series

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Pulmonary hypertension in COPD
A. Chaouat, R. Naeije, E. Weitzenblum

European Respiratory Journal 32 (5) 1371-1385; DOI: 10.1183/09031936.00015608 Published 31 October 2008
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Carotid body oxygen sensing
J. López-Barneo, P. Ortega-Sáenz, R. Pardal, A. Pascual, J. I. Piruat

European Respiratory Journal 32 (5) 1386-1398; DOI: 10.1183/09031936.00056408 Published 31 October 2008

Case Study

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Pathomechanisms of cyst formation in pulmonary light chain deposition disease
M. Colombat, S. Caudroy, E. Lagonotte, H. Mal, C. Danel, M. Stern, M. Fournier, P. Birembaut

European Respiratory Journal 32 (5) 1399-1403; DOI: 10.1183/09031936.00132007 Published 31 October 2008

Case For Diagnosis

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A 29-year-old male with chest pain and haemoptysis
E. C. Young, N. L. Mills, P. A. Henriksen, J. T. Murchison, D. M. Salter, R. L. Hayward, D. E. Newby, A. J. Simpson

European Respiratory Journal 32 (5) 1404-1407; DOI: 10.1183/09031936.00016108 Published 31 October 2008

Correspondence

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The validation of assays used to measure biomarkers in exhaled breath condensate
E. Sapey, D. Bayley, A. Ahmad, R. Stockley

European Respiratory Journal 32 (5) 1408-1409; DOI: 10.1183/09031936.00088608 Published 31 October 2008
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From the authors
P. P. Rosias, E. Dompeling

European Respiratory Journal 32 (5) 1409; DOI: 10.1183/09031936.00101608 Published 31 October 2008
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Assessing small airways disease
J. Hansen

European Respiratory Journal 32 (5) 1410; DOI: 10.1183/09031936.00088908 Published 31 October 2008
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From the authors
J. Cohen, N. R. Douma, N. H. T. ten Hacken, D. S. Postma

European Respiratory Journal 32 (5) 1410-1411; DOI: 10.1183/09031936.00101508 Published 31 October 2008
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A possible role for Epstein–Barr virus infection in COPD?
A. W. J. Bossink, M. Deege, S. F. T. Thijsen

European Respiratory Journal 32 (5) 1411-1412; DOI: 10.1183/09031936.00096308 Published 31 October 2008
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To the Editors
W. B. Grant

European Respiratory Journal 32 (5) 1412-1413; DOI: 10.1183/09031936.00098608 Published 31 October 2008
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From the authors
T. E. McManus, S. Elborn, H. J. O’Neill, P. V. Coyle, J. Kidney

European Respiratory Journal 32 (5) 1413; DOI: 10.1183/09031936.00103608 Published 31 October 2008
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Extensively drug-resistant tuberculosis: is its definition correct?
J. A. Caminero

European Respiratory Journal 32 (5) 1413-1415; DOI: 10.1183/09031936.00094708 Published 31 October 2008
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An ecological analysis of incidence of tuberculosis and per capita gross domestic product
J-P. Janssens, H. L. Rieder

European Respiratory Journal 32 (5) 1415-1416; DOI: 10.1183/09031936.00078708 Published 31 October 2008
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Diagnosis of pulmonary thromboembolism with endobronchial ultrasound
G. L. Casoni, C. Gurioli, M. Romagnoli, V. Poletti

European Respiratory Journal 32 (5) 1416-1417; DOI: 10.1183/09031936.00075208 Published 31 October 2008
Supplementary video
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Pneumonia in the context of severe sepsis: a significant diagnostic problem
T. Bewick, M. Simmonds, M. Chikhani, J. Meyer, W. S. Lim

European Respiratory Journal 32 (5) 1417-1418; DOI: 10.1183/09031936.00104808 Published 31 October 2008
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Assessing asthma control: questionnaires and exhaled nitric oxide provide complementary information
C. Lopes, J. Fonseca, L. Delgado, A. Moreira, R. Barros, P. Moreira, M. da G. Castelo-Branco

European Respiratory Journal 32 (5) 1419-1420; DOI: 10.1183/09031936.00093008 Published 31 October 2008
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Breathless after separation… from tumour
S-B. Catrina, L. Juntti-Berggren

European Respiratory Journal 32 (5) 1420-1421; DOI: 10.1183/09031936.00096008 Published 31 October 2008
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Statistical analysis of COPD exacerbations
O. N. Keene, P. M. A. Calverley, P. W. Jones, J. Vestbo, J. A. Anderson

European Respiratory Journal 32 (5) 1421-1422; DOI: 10.1183/09031936.00123408 Published 31 October 2008
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To the Editors
D. Liu, S. Menjoge

European Respiratory Journal 32 (5) 1422-1423; DOI: 10.1183/09031936.00124108 Published 31 October 2008
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From the authors
O. N. Keene, P. M. A. Calverley, P. W. Jones, J. Vestbo, J. A. Anderson

European Respiratory Journal 32 (5) 1423; DOI: 10.1183/09031936.00135008 Published 31 October 2008
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Is air travel safe for those with lung disease?
R. K. Coker, R. Shiner, M. R. Partridge

European Respiratory Journal 32 (5) 1423-1424; DOI: 10.1183/09031936.00133108 Published 31 October 2008

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Table of Contents

Editorial

Perspective

Original Articles: Rapid communication: lung cancer

Original Articles: Clinical forum: tuberculosis

Original Articles: Bench to bedside: breatheomics

Original Articles: Respiratory cell biology

Original Articles: Wheezy infants

Original Articles: Airway remodelling

Original Articles: Asthma

Original Articles: Paediatric asthma and rhinitis

Original Articles: Paediatric lung function

Original Articles: COPD

Original Articles: Steroids and bacterial infection

Original Articles: Pulmonary hypertension

Original Articles: Environmental exposures

Original Articles: Sleep-disordered breathing

Original Articles: Genetics of pneumothorax

Original Articles: Pleural effusion

Original Articles: Mechanical ventilation

Original Articles: Lung injury

Review

Series

Case Study

Case For Diagnosis

Correspondence

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