First author [Ref.] | Cost measure | Comment |
Abele-Horn
8
| Patients treated with antibiotics | Significantly reduced |
| Antibiotic expenditure | Reduced |
| Antibiotic cost·day−1·patient−1 | Significantly reduced |
| Antibiotic cost·patient−1 treated | Significantly reduced |
| Ventilation cost·day−1 | No difference |
Bion
9
| Total nonprophylactic antibiotic cost·day−1·patient-1 | Reduced |
| Total antibiotic cost·day−1·patient-1 | Increased |
Gastinne
10
| Total charge for systemic antibiotics | No difference |
| Mean charge·patient-1 to treat respiratory infection | Reduced |
| Mean total charge for antibiotics | Significantly increased |
Georges
11
| Antibiotic cost·day−1·patient−1 | Reduced |
| Total antibiotic cost·day−1·patient-1, SDD included | Significantly increased |
Hellinger
12
| Total charges for medical care after liver transplantation | No difference |
de Jonge
6
| Total cost of prescribed antibiotics | Reduced |
Korinek
13
| Total cost of parenteral antibiotics for acquired infections | Reduced |
| Antibiotic cost·patient−1 infected | No difference |
| Cost per patient | Reduced |
| Cost per survivor | Reduced |
Krueger
14
| Antibiotic cost·patient−1 | Reduced |
| Total antibiotic cost·day−1·patient-1, SDD included | Increased |
| Therapeutic intervention scoring system points | Significantly reduced |
Lingnau
15
| Mean antibiotic cost·patient−1 to treat infectious complications | Significantly reduced |
Quinio
16
| Antibiotic expenditure, SDD included | Significantly reduced |
Rocha
17
| Overall antibiotic cost | Significantly reduced |
| Antibiotic cost·day−1·patient−1 | Significantly reduced |
| Cost per survivor | Reduced |
Rolando
18
| Antibiotic cost | No difference |
Sánchez García 19 | Cost of systemic antibiotics | Significantly reduced |
| Cost per survivor | Significantly reduced |
Shardey
20
| Total antibiotic expenditure | Significantly reduced |
| Patients receiving antibiotics | Significantly reduced |
Stoutenbeek
21
| Cost per survivor | Reduced |
Zwaveling
22
| Medical care cost | No differences |