To the Editors:
We would like to describe the case of a patient who was treated with clarithromycin for community-acquired pneumonia (CAP). She presented with an episode of agitation and delirium while taking the clarithromycin, but this disappeared when the clarithromycin was stopped. This case is interesting because of the low frequency of symptoms of the central nervous system during the treatment.
The patient was a 63-yr-old female, with pathological history of arterial hypertension. She was treated with angiotensin-converting enzyme inhibitor and a pacemarker for atrial block and had no previous psychiatric history. The patient went to the emergency department in a poor general state; she had had a fever for 7 days and developed chills. Once at home, she was treated with paracetamol. A physical examination revealed a fever (39°C), blood pressure of 120/60 mmHg and heart frequency of 70 beats·min-1. She had crepitations at the left hemithorax and cardiac arrhythmic …