Tables
- Table 1—
Characteristics of patients with bronchiectasis according to nontuberculous mycobacterial(NTM) lung disease
Characteristics With NTM# Without NTM¶ p-value+ Mean age yrs 62.2±14.6 51.6±15.3 0.002 Sex Male 9 23 0.46 Female 21 38 Underlying aetiology of bronchiectasis§ Idiopathic 10 27 0.002 Post-tuberculosis 4 0 Post-adult infection 1 10 Post-childhood infection 2 8 Rheumatoid arthritis 2 1 Primary ciliary dyskinesia 3 7 Diffuse pan-bronchiolitis 0 2 Allergic bronchopulmonary Aspergillosis 4 3 Yellow nail syndrome 0 3 Miscellaneous 4 0 Pulmonary function tests FEV1 L 1.6±0.8 2.0±0.8 0.02 RV % pred 147±35 152±45 0.62 TL,CO % pred 67±25 77±15 0.05 Data are presented as mean±sd or n. FEV1: forced expiratory volume in one second; RV: residual volume; % pred: % predicted; TL,CO: transfer factor of the lung for carbon monoxide. #: n = 30; ¶: n = 61; +: univariate analysis using Chi-squared or Fisher's exact test for contingency tables and unpaired t-test for comparison of means; §: the most predominant aetiology reported; some patients had two aetiologies.
- Table 2—
Features of Aspergillus-related lung disease in patients with bronchiectasis according to nontuberculous mycobacteria (NTM) lung disease
NTM lung disease p-value# Yes No Total subjects 30 61 Eosinophil count/total IgE Eosinophilia >0.5 2 3 1.0 IgE >150 4 14 0.27 Size of IgE among positives 2740±2709 835±1520 0.08 Positive serology for Aspergillus-related lung disease¶ Total patients with positive serology 10 6 0.005 Positive A. fumigatus precipitins and RAST 3 1 0.10 Positive A. fumigatus precipitins 10 4 0.003 1 line 2 1 2 lines 6 3 3 lines 2 0 Positive A. fumigatus RAST 3 2 0.32 Radiological features suggestive of Aspergillus-related lung disease 6 0 0.003 Invasive aspergillosis/CNPA 1 Probable aspergilloma 3 0 Definite aspergilloma 2 0 Clinical and serological features consistent with ABPA ABPA 4 3 0.2 ABPA, aspergilloma 1 0 Data are presented as n or mean±sd. Ig: immunoglobulin; A. fumigatus: Aspergillus fumigatus; RAST: radioallergosorbent test; CNPA: chronic necrotising pulmonary aspergillosis; ABPA: allergic bronchopulmonary aspergillosis. #: univariate analysis using Chi-squared or Fisher's exact test for contingency tables and unpaired t-test for comparison of means; ¶: see Methods section for details.
- Table 3—
Logistic regression estimates of the association between nontuberculous mycobacteria(NTM) lung disease and Aspergillus-related lung disease
Independent variable Simple regression Multiple regression# OR (95% CI) p-value OR (95% CI) p-value NTM lung disease yes/no 7.01 (2.3–21.1) 0.0005 5.1 (1.5–17.0) 0.008 FEV1 L 0.25 (0.10–0.64) 0.003 0.34 (0.13–0.89) 0.028 OR: odds ratio; CI: confidence interval; FEV1: forced expiratory volume in one second. #: multiple logistic regression model with Aspergillus-related lung disease (serology and radiology combined) as the binary dependent variable and NTM lung disease, age and FEV1 as independent variables. Age did not contribute significantly to the model. See the Methods section for details.
