Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions

Predictors of success and failure in pulmonary rehabilitation

R. Garrod, J. Marshall, E. Barley, P. W. Jones
European Respiratory Journal 2006 27: 788-794; DOI: 10.1183/09031936.06.00130605
R. Garrod
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J. Marshall
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
E. Barley
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P. W. Jones
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Figures

  • Tables
  • Fig. 1—
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig. 1—

    Changes in primary outcomes of the following: a) 6-minute walking distance, b) quadriceps strength, c) St George's Respiratory Questionnaire total and d) depression.

Tables

  • Figures
  • Table 1—

    Baseline characteristics by disease severity

    Subjects nDisease severityp-value
    Mild (MRC grade 1/2)#Moderate (MRC grade 2/3)¶Severe (MRC grade 5)+
    Age yrs7463.6±11.467.9±9.673.2±7.90.005
    BMI kg·m−2§7426.3±5.229.2±8.725.8±5.5ns
    Smoking pack-yrs§7338.1±28.048.8±39.351.7±30.9ns
    6MWD % pred7371.3±14.250.2±18.227.7±15.8<0.0001
    Quadriceps torque (Nms/kg×100)74123.5±35.5123.0±55.083.9±36.80.003
    SGRQ score§7438.0±14.861.2±12.965.5±14.2<0.0001
    FEV1 % pred7365.7±20.043.0±24.438.1±16.9<0.0001
    FVC % pred7383.7±20.765.6±19.766.4±23.80.008
    MIP % pred6674.4±35.872.2±31.659.4±19.3ns
    MEP % pred6698.2±44.087.9±32.177.4±34.6ns
    V′O2,max kg·L−1·min−17116.2±7.010.9±6.07.1±1.9<0.0001
    Grip % pred74109.9±17.6102.6±24.099.3±25.1ns
    Borg score pre-6MWD m§720.2±0.30.7±0.71.0±1.10.009
    Borg score post-6MWD m§723.1±1.43.7±0.94.5±1.50.002
    Sa,O2 pre-6MWD %7395.9±2.193.8±3.092.5±3.30.001
    Sa,O2 post-6MWD %7394.5±3.891.0±6.288.5±6.20.003
    COPDSE723.4±1.02.9±0.92.7±0.90.03
    LCADL§7419.3±10.433.6±14.346.2±16.4<0.0001
    • Differences were tested using ANOVA. Data are presented as mean (sd). A high score indicates better health, unless otherwise indicated (§: low score = better health). MRC: Medical Research Council; BMI: body mass index; 6MWD: 6-minute walk distance; SGRQ: St George's Respiratory Questionnaire; FEV1: forced expiratory volume in one second; % pred: per cent predicted; FVC: forced vital capacity; MIP: maximal inspiratory pressure; MEP: maximal expiratory pressure; V′O2,max: maximal oxygen consumption; Sa,O2: arterial oxygen saturation; COPDSE: Chronic Obstructive Pulmonary Disease Self-Efficacy Scale; LCADL: London Chest Activity of Daily Living Scale. #: n = 21; ¶: n = 29; +: n = 24; ns: nonsignificant.

  • Table 2—

    Changes in health following pulmonary rehabilitation for patients with mild, moderate or severe disease

    Subjects nDisease severityp-value
    Mild (MRC grade 1/2)Moderate (MRC grade 2/3)Severe (MRC grade 5)
    6MWD % pred of normative values517.8±6.510.0±11.35.2±11.90.003
    6MWD m5154.7±45.068.0±74.232.6±74.80.002
    Quadriceps torque Nms511.6±19.63.1±33.86.5±18.7ns
    SGRQ score#51-7.5±10.3-7.0±8.40.7±11.20.03
    MIP % pred4811.1±22.92.7±10.31.9±10.5ns
    MEP % pred49-0.0±22.710.1±17.911.3±31.5ns
    Grip % pred51-0.9±11.43.1±12.3-0.6±19.8ns
    COPDSE490.4±0.50.1±0.90.1±0.7ns
    LCADL#51-0.4±3.9-1.1±7.50.7±8.5ns
    • Data are presented as mean difference±sd between follow-up and baseline. A positive score = improvement, unless otherwise indicated (#: negative score = improvement). p-values represent the significance of disease severity in a generalised linear model with score at follow-up as the dependent variable, disease severity as the independent variable and baseline score as a covariate (nonsignificant (ns) = p>0.05). MRC: Medical Research Council; 6MWD: 6-minute walk distance; SGRQ = St George's Respiratory Questionnaire; MIP: maximal inspiratory pressure; MEP: maximal expiratory pressure; COPDSE: Chronic Obstructive Pulmonary Disease Self-Efficacy Scale; LCADL: London Chest Activity of Daily Living Scale.

  • Table 3—

    Relationship between baseline variables and change in outcomes

    Δ6MWD %ΔQuadsΔSGRQ
    Age yrs−0.1−0.00.2
    BMI kg·m−20.2−0.2−0.1
    Smoking pack-yrs−0.10.10.0
    6MWD % pred−0.3#−0.1−0.4¶
    Quadriceps maximum torque Nms−0.2−0.1−0.2
    Quadriceps Nms·kg−1×100−0.4¶−0.1−0.1
    SGRQ total0.2−0.1−0.0
    FEV1 % pred−0.0−0.4¶−0.1
    FVC % pred−0.1−0.30.0
    MIP % pred0.1−0.2−0.2
    MEP % pred−0.1−0.2−0.1
    V′O2,max kg·L−1·min−1−0.10.0−0.2
    MVV−0.0−0.3−0.2
    MVV/V′E−0.20.2−0.1
    Grip % pred0.0−0.00.0
    Borg score pre-6MWD m0.20.10.1
    Borg score post-6MWD m−0.20.10.2
    Sa,O2 pre-6MWD %−0.4¶−0.3−0.2
    Sa,O2 post-6MWD %0.1−0.4¶−0.2
    Heart rate pre-6MWD−0.4¶−0.10.1
    Heart rate post-6MWD−0.30.10.0
    COPDSE−0.3#0.1−0.0
    LCADL0.20.00.2
    • 6MWD: 6-minute walking distance; SGRQ: St George's Respiratory Questionnaire; BMI: body mass index; FEV1: forced expiratory volume in one second; % pred: per cent predicted; FVC: forced vital capacity; MIP: maximal inspiratory pressure; MEP: maximal expiratory pressure; V′O2,max: maximum oxygen consumption; MVV/V′E: maximal voluntary ventilation/ventilation ratio; Sa,O2: arterial oxygen saturation; COPDSE: Chronic Obstructive Pulmonary Disease Self-Efficacy Scale; LCADL: London Chest Activity of Daily Living Scale. Borg pre-6MWD values were log transformed in order to achieve a normal distribution prior to analysis. #: p<0.05; ¶: p≤0.01.

  • Table 4—

    Percentage of patients completing pulmonary rehabilitation with a clinically significant change in St George's Respiratory Questionnaire (SGRQ) score (reduction of ≥4 units) and 6-minute walking distance (6MWD; increase of ≥54 m) stratified by the Medical Research Council dyspnoea score (MRC) grade.

    TotalDisease severity
    Mild (MRC grade 1/2)Moderate (MRC grade 2/3)Severe (MRC grade 5)
    Subjects n51162213
    6MWD ≥54 m47815946
    SGRQ score# ≥4 units63505039
    Composite responders77888254
    • Data are presented as % or n. There was no difference between the groups in the number of patients who had changed significantly (p>0.05). Composite: percentage of patients completing pulmonary rehabilitation with a clinically significant change in either SGRQ score (a reduction of ≥4 units) or 6MWD (an increase of ≥54 m) stratified by MRC grade.

PreviousNext
Back to top
View this article with LENS
Vol 27 Issue 4 Table of Contents
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Predictors of success and failure in pulmonary rehabilitation
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
Citation Tools
Predictors of success and failure in pulmonary rehabilitation
R. Garrod, J. Marshall, E. Barley, P. W. Jones
European Respiratory Journal Apr 2006, 27 (4) 788-794; DOI: 10.1183/09031936.06.00130605

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Predictors of success and failure in pulmonary rehabilitation
R. Garrod, J. Marshall, E. Barley, P. W. Jones
European Respiratory Journal Apr 2006, 27 (4) 788-794; DOI: 10.1183/09031936.06.00130605
del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo
Full Text (PDF)

Jump To

  • Article
    • Abstract
    • METHODS
    • RESULTS
    • DISCUSSION
    • Acknowledgments
    • References
  • Figures & Data
  • Info & Metrics
  • PDF
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

  • Maintaining benefits following pulmonary rehabilitation: a randomised controlled trial
  • COPD patients' ability to follow exercise influences short-term outcomes of rehabilitation
  • Noninvasive ventilation during walking in patients with severe COPD: a randomised cross-over trial
Show more Original Articles: Pulmonary rehabilitation

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Reviewers
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Publication ethics and malpractice
  • Submit a manuscript

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2022 by the European Respiratory Society