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Self-management reduces both short- and long-term hospitalisation in COPD

M-A. Gadoury, K. Schwartzman, M. Rouleau, F. Maltais, M. Julien, A. Beaupré, P. Renzi, R. Bégin, D. Nault, J. Bourbeau
European Respiratory Journal 2005 26: 853-857; DOI: 10.1183/09031936.05.00093204
M-A. Gadoury
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K. Schwartzman
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M. Rouleau
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F. Maltais
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M. Julien
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A. Beaupré
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P. Renzi
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R. Bégin
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D. Nault
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J. Bourbeau
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  • Fig. 1—
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    Fig. 1—

    Trial profile based on hospitalisation, collected from a provincial hospitalisation database. #: these patients were included in the 2nd yr because they experienced emergency room visits or hospitalisations.

Tables

  • Figures
  • Table. 1—

    Baseline characteristics of the study patients

    Intervention groupUsual care group
    Subjects n9695
    Age yrs69.4±6.569.6±7.4
    Sex male50 (52)56 (59)
    Living alone46 (48)40 (42)
    Education ≤12th grade79 (82)73 (77)
    Current smoker24 (25)25 (26)
    Smoking pack-yrs57.8±40.656.1±31.3
    FEV1 L0.98±0.311.00±0.33
    FEV1/FVC ratio0.46±0.100.45±0.12
    Dyspnoea MRC 5/544 (46)47 (49)
    6-min walk test m282±91280±90
    SGRQ#54.1±16.655.7±15.7
    • Data are presented as mean±sd or n (%), unless otherwise stated. FEV1: forced expiratory volume in one second; FVC: forced vital capacity; MRC: Medical Research Council; SGRQ: St George's Respiratory Questionnaire. #: lower score on the questionnaire indicates better health status.

  • Table. 2—

    Comparison of all-cause hospitalisation(s) between study groups in the year preceding enrolment and for 2 yrs' follow-up

    Preceding yearStudy year2nd yr follow-up
    Self-managementStandard careSelf-managementStandard careSelf-managementStandard care
    Admissions n12613389148104132
    Patient-yrs n969593.989.786.279.9
    Hospitalisations·patient-yr−11.301.400.951.651.211.65
    Reduction in hospitalisations·patient-yr−1#−0.10 (−0.27–0.07)−0.70 (−0.95– −0.46)−0.44 (−0.68– −0.21)
    Treatment difference¶ %−6.3−42.6−26.9
    • #: reduction in the rate of all-cause hospitalisations in the self-management group as compared to the standard-care group (95% confidence interval); ¶: differences were calculated by dividing the absolute difference between groups by the standard-care group value.

  • Table. 3—

    Comparison of all-cause emergency room (ER) visits between study groups in the year preceding enrolment and for 2 yrs' follow-up

    Preceding yearStudy year2nd yr follow-up
    Self-managementStandard careSelf-managementStandard careSelf-managementStandard care
    ER visits n256268211317217255
    Patient-yrs969593.989.786.279.9
    ER visits·patient-yr−12.72.82.23.52.53.2
    Reduction in ER visits·patient-yr−1#−0.1 (−0.21–0.02)−1.3 (−1.18– −1.42)−0.7 (−0.58– −0.82)
    Treatment difference¶ %−5.5−36.5−21.1
    • #: reduction in the rate of all-cause ER visits in the self-management group as compared to the standard-care group (95% confidence interval); ¶: differences were calculated by dividing the absolute difference between groups by the standard-care group value.

  • Table. 4—

    Predictive factors of all-cause hospitalisations during the 1st and 2nd yrs of follow-up after adjustment for the intervention

    VariableAdjusted OR95% CI
    Age#1.051.03–1.06
    Sex¶0.690.55–0.86
    SGRQ+1.0151.008–1.022
    6-min walk test§0.9980.997–0.999
    Education levelƒ0.810.73–0.90
    • OR: odds ratio; CI: confidence interval. #: age is treated as a continuous variable (per increased year); ¶: difference for female when compared to male; +: difference per one-point increase (reduced health status) using the St George's Respiratory Questionnaire (SGRQ); §: 6-min walk test is given per increased metre on walking distance; ƒ: education level is treated as a five-category variable (from high to low).

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Self-management reduces both short- and long-term hospitalisation in COPD
M-A. Gadoury, K. Schwartzman, M. Rouleau, F. Maltais, M. Julien, A. Beaupré, P. Renzi, R. Bégin, D. Nault, J. Bourbeau
European Respiratory Journal Nov 2005, 26 (5) 853-857; DOI: 10.1183/09031936.05.00093204

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Self-management reduces both short- and long-term hospitalisation in COPD
M-A. Gadoury, K. Schwartzman, M. Rouleau, F. Maltais, M. Julien, A. Beaupré, P. Renzi, R. Bégin, D. Nault, J. Bourbeau
European Respiratory Journal Nov 2005, 26 (5) 853-857; DOI: 10.1183/09031936.05.00093204
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