To the Editors:
The topic of long term oxygen therapy (LTOT) has been a great interest to our group, beginning with our first report in 1967 1. Here, we showed a marked increase in exercise capability with use of ambulatory oxygen (AO) in selected patients with advanced chronic obstructive pulmonary disease (COPD). By contrast, the carefully carried out, randomised, controlled study of AO in oxygen-dependent patients, recently published in the European Respiratory Journal, concludes that AO is not associated with increased walk tolerance or improved quality of life …
