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From the author

C.B.E. Chee
European Respiratory Journal 2005 25: 1128; DOI: 10.1183/09031936.05.00020505
C.B.E. Chee
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We thank V. Poletti and G.L. Casoni for their comments and interest in our case report 1.

Acute fibrinous and organising pneumonia is certainly a possible differential diagnosis in our patient. However, the patient's subacute presentation, dramatic response to steroids and clinical course were more in keeping with, and indeed typical of, cryptogenic organising pneumonia. In contrast, in the original series by Beasley et al. 2, of 17 patients with the histological diagnosis of acute fibrinous and organising pneumonia, nine patients had a fulminant course with rapid progression to death. Of the seven patients in this series who were treated with steroids (with or without antibiotics), only two survived. It should also be noted that the histological diagnosis of acute fibrinous and organising pneumonia was made from open lung and autopsy specimens in all cases.

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    References

    1. ↵
      Chee CBE, Da Costa JL, Sim CS. A female with dry cough, progressive dyspnoea and weight loss. Eur Respir J 2005;25:206–209.
      OpenUrlFREE Full Text
    2. ↵
      Beasley MB, Franks TJ, Galvin JR, Gochuico B, Travis WD. Acute fibrinous and organizing pneumonia: a histological pattern of lung injury and possible variant of diffuse alveolar damage. Arch Pathol Lab Med 2002;126:1064–1070.
      OpenUrlPubMedWeb of Science
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    C.B.E. Chee
    European Respiratory Journal Jun 2005, 25 (6) 1128; DOI: 10.1183/09031936.05.00020505

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    C.B.E. Chee
    European Respiratory Journal Jun 2005, 25 (6) 1128; DOI: 10.1183/09031936.05.00020505
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