Fig. 3— Losartan therapy does not alter the diffuse interstitial fibrosis and chronic inflammation of bleomycin-treated mice. Serial lung sections from control (a and b), control+losartan (c and d), bleomycin (e and f) and bleomycin+losartan (g and h) were analysed with Masson's trichrome (a, c, e ,g) and haematoxylin and eosin (b, d, f, h) stains. Lung sections obtained from mice following bleomycin exposure demonstrated diffuse interstitial fibrosis and chronic inflammation. Losartan therapy did not discernibly alter inflammation or fibrosis in these mice. Scale bars = 1000 μm.