Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • For authors
    • Instructions for authors
    • Submit a manuscript
    • Author FAQs
    • Open access
    • COVID-19 submission information
  • Alerts
  • Podcasts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • For authors
    • Instructions for authors
    • Submit a manuscript
    • Author FAQs
    • Open access
    • COVID-19 submission information
  • Alerts
  • Podcasts
  • Subscriptions

Relationship between pulmonary function and lung cancer surgical outcome

T. Win, A. Jackson, L. Sharples, A. M. Groves, F. C. Wells, A. J. Ritchie, C. M. Laroche
European Respiratory Journal 2005 25: 594-599; DOI: 10.1183/09031936.05.00077504
T. Win
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Jackson
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L. Sharples
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. M. Groves
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
F. C. Wells
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. J. Ritchie
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C. M. Laroche
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Figures

  • Tables
  • Fig. 1—
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig. 1—

    Receiver-operating characteristic curves (––––: baseline forced expiratory volume in one second (FEV1; L; area under the curve (AUC) 0.587); ------: baseline FEV1 (% pred; AUC 0.731); –– - ––: baseline carbon monoxide diffusing capacity of the lung (DL,CO; % pred; AUC 0.701); –– - - ––: baseline predicted post-operative (ppo) FEV1 (L; by ventilation/perfusion (V′/Q′) scan; AUC 0.587); -- --: baseline ppo DL,CO (% pred; by V′/Q′ scan; AUC 0.772); – – –: predicted post-operative product (PPP; AUC 0.792); –– ––: baseline ppo FEV1 (% pred; by V′/Q′ scan; AUC 0.752); ·········: reference line (AUC 0.5). Diagonal segments are produced by ties. The PPP is the product of ppo FEV1 and ppo DL,CO (both % pred).

Tables

  • Figures
  • Table. 1—

    Pulmonary function data of lung cancer surgery patients#

    FEV1 L2.0±0.7 (1.0–4.7)
    FEV1 % pred79.4±20.3 (37–119)
    FVC L3.3±0.9 (2–6)
    FVC % pred101±17.3 (56–155)
    DL,CO % pred73.6±18.0 (33–122)
    DL,CO/VA % pred85.9±20.4 (37–157)
    TLC % pred106.5±15.2 (66–144)
    ppo FEV1 L1.4±0.5 (0.6–3.6)
    ppo FEV1 % pred55.6±15.4 (22–95)
    ppo DL,CO % pred51.3±14.9 (21–92)
    PPP2990±1445 (560–8423)
    • Data are presented as mean±sd (range). FEV1: forced expiratory volume in one second; % pred: percentage of the predicted value; FVC: forced vital capacity; DL,CO: carbon monoxide diffusing capacity of the lung; VA: alveolar volume; TLC: total lung capacity; ppo FEV1: predicted post-operative FEV1; ppo DL,CO: predicted post-operative DL,CO; PPP: predicted post-operative product (product of ppo FEV1 and ppo DL,CO (both % pred)). #: n = 110.

  • Table. 2—

    Frequency of major complications comprising complicated post-operative course and poor outcome

    ComplicationComplicated coursePoor outcome
    Subjects# n2814
    Death within 30 days44
    Myocardial infarction3
    Cardiac failure3
    Renal failure3
    Respiratory failure1111
    Sepsis3
    Pneumonia21
    Pulmonary embolism2
    • Data are presented as n. #: some had more than one major complication.

  • Table. 3—

    Pulmonary function data for patients with and without a complicated post-operative course

    UncomplicatedComplicatedDifference (95% CI)p-value
    Subjects n8228
    FEV1 L2.0±0.61.9±0.80.1 (−0.2–0.4)0.44
    FEV1 % pred82.9±19.569.6±19.413.4 (4.9–21.8)0.002
    FVC L3.2±0.83.4±1.0−0.2 (−0.6–0.2)0.24
    FVC % pred102.4±17.796.7±15.65.7 (-1.8–13.2)0.13
    DL,CO % pred76.4±17.965.0±15.911.4 (3.9–19.1)0.004
    ppo FEV1 L1.4±0.51.3±0.50.1 (−0.1–0.3)0.34
    ppo FEV1 % pred58.0±14.549.2±16.48.8 (3.3–15.3)0.009
    ppo DL,CO % pred53.8±14.844.8±13.19.0 (2.5–15.4)0.007
    PPP3228±14282346±1309882 (257–1507)0.006
    • Data are presented as mean±sd, unless otherwise stated. CI: confidence interval; FEV1: forced expiratory volume in one second; % pred: percentage of the predicted value; FVC: forced vital capacity; DL,CO: carbon monoxide diffusing capacity of the lung; ppo FEV1: predicted post-operative FEV1; ppo DL,CO: predicted post-operative DL,CO; PPP: predicted post-operative product (product of ppo FEV1 and ppo DL,CO (both % pred)).

  • Table. 4—

    Pulmonary function data for patients with and without a poor outcome

    Satisfactory outcomePoor outcomeDifference (95% CI)p-value
    Subjects n9614
    FEV1 L2.0±0.61.9±0.90.2 (−0.2–0.5)0.42
    FEV1 % pred81.8±19.563.0±18.418.8 (7.8–29.8)0.001
    FVC L3.2±0.83.6±1.1−0.3 (−0.8–0.2)0.18
    FVC % pred102.0±17.993.6±10.38.4 (-1.3–18.1)0.01
    DL,CO % pred75.7±17.159.7±17.715.9 (6.2–25.7)0.002
    ppo FEV1 L1.4±0.51.±0.50.2 (−0.1–0.5)0.12
    ppo FEV1 % pred57.7±14.742.0±13.015.7 (7.5–24.0)<0.001
    ppo DL,CO % pred53.5±14.637.9±8.315.6 (7.6–23.5)<0.001
    PPP3209±14171644±7051564 (796–2333)<0.001
    • Data are presented as mean±sd, unless otherwise stated. CI: confidence interval; FEV1: forced expiratory volume in one second; % pred: percentage of the predicted value; FVC: forced vital capacity; DL,CO: carbon monoxide diffusing capacity of the lung; ppo FEV1: predicted post-operative FEV1; ppo DL,CO: predicted post-operative DL,CO; PPP: predicted post-operative product (product of ppo FEV1 and ppo DL,CO (both % pred)).

PreviousNext
Back to top
View this article with LENS
Vol 25 Issue 4 Table of Contents
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Relationship between pulmonary function and lung cancer surgical outcome
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
Alerts
Sign In to Email Alerts with your Email Address
Citation Tools
Relationship between pulmonary function and lung cancer surgical outcome
T. Win, A. Jackson, L. Sharples, A. M. Groves, F. C. Wells, A. J. Ritchie, C. M. Laroche
European Respiratory Journal Apr 2005, 25 (4) 594-599; DOI: 10.1183/09031936.05.00077504

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Relationship between pulmonary function and lung cancer surgical outcome
T. Win, A. Jackson, L. Sharples, A. M. Groves, F. C. Wells, A. J. Ritchie, C. M. Laroche
European Respiratory Journal Apr 2005, 25 (4) 594-599; DOI: 10.1183/09031936.05.00077504
del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo
Full Text (PDF)

Jump To

  • Article
    • Abstract
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • References
  • Figures & Data
  • Info & Metrics
  • PDF
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

  • Morbidity and mortality in the surgery arm of EORTC 08941 trial
Show more Original Articles: Clinical forum: Lung cancer

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Reviewers
  • CME
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Submit a manuscript
  • ERS author centre

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2021 by the European Respiratory Society