Figures
- Fig. 1.—
Survival curves of kyphoscoliotic patients treated with long-term oxygen therapy at home (LTO) or LTO and nocturnal nasal intermittent positive pressure ventilation at home (nNIPPV). ♦: LTO group; ▴: nNIPPV group.
- Fig. 2.—
Correlation between the increase in vital capacity (VC) and the increase in maximal inspiratory mouth pressure (MIP) in patients on nocturnal nasal intermittent positive pressure ventilation and long-term oxygen therapy at home. #: (value before treatment–value after treatment)/value before treatment.
Tables
- Table 1—
Pulmonary function and daytime blood gases (breathing air) prior to treatment (baseline) and when on treatment during at least 6 months (end)
LTO group# nNIPPV group¶ Difference between LTO and nNIPPV group p‐values Baseline End Δ§ Baseline End Δ§ Baseline End Δ§ n mean±sd n mean±sd n mean±sd n mean±sd n mean±sd n mean±sd Age yrs 15 62±7 18 61±7 ns Height cm 15 153±14 18 145±11 ns FEV1/VC 15 78±18 18 82±12 ns PO2 on air mmHg 15 50±7 11+ 56±9 11+ 13±13 18 44±8 18 66±10 18 54±34 <0.05 0.01 0.001 PCO2 on air mmHg 15 55±7 11+ 52±5 11+ 0±6 18 60±8 18 47±8 18 −21±11 NS 0.01 0.0001 VC % pred 15 40±16 9+ 46±16 9+ 6±23 18 32±12 18 44±10 18 47±44 NS NS <0.01 VC mL 15 970±387 9+ 1064±452 9+ 4±24 18 645±244 18 830±292 18 51±53 <0.01 NS <0.01 MIP % pred NA 12 44±13 12 57±17 12 33±30 MIP kPa NA 12 3.7±1.1 12 4.8±1.2 12 34±31 -
LTO: long-term oxygen therapy at home
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nNIPPV: nocturnal nasal intermittent positive pressure ventilation at home
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FEV1: forced expiratory volume in one second
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VC: vital capacity
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PO2: partial pressure of oxygen
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PCO2: partial pressure of carbon dioxide
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MIP: maximal inspiratory muscle force
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NA: not available
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ns: nonsignificant
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#: LTO group (10 males and five females)
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¶: nNIPPV group (14 males and four females)
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+: four patients died before re-evaluation was possible and in two remaining patients a spirometric measurement was not possible
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§: (value before treatment–value after start of treatment)/value before treatment
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Conversion factor mmHg to kPa×0.133
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