Fig. 2.—
Result of bronchial provocation test by inhalation of humidifier water. The carbon monoxide diffusing capacity of the lung (open circles), forced expiratory volume in one second (closed circles), and forced vital capacity (open squares) decreased maximally at 4–8 h after provocation. Elevation in body temperature, leucocytosis and corresponding hypoxia were also observed. Solid arrow: control; dashed arrow: provocation. 0 h: body temperature (BT°C): 36.1, WBC·mm−3: 7,940, oxygen tension in arterial blood (Pa,O2): 9.86 kPa (74.1 Torr); 4 h: BT°C: 37.5, white blood cell count (WBC·mm−3): 7,520, Pa,O2: 8.09 kPa (60.8 Torr); 8 h: BT°C: 38.1, WBC·mm−3: 19,830, Pa,O2: 8.37 kPa (62.9 Torr); 24 h: BT°C: 38.8, WBC·mm−3: 16,200, Pa,O2: 8.63 kPa (64.9 Torr).