Figures
- Fig. 1.—
a) Flow chart of patients on long-term oxygen therapy and b) the division of the four groups. COPD: chronic obstructive pulmonary disease; COT: continuous oxygen therapy; NCOT: noncontinuous oxygen therapy; hypoxemic status: oxygen tension in arterial blood <7.3 kPa (50 mmHg) or 7.3–8.0 kPa (50–60 mmHg) together with cor pulmonale according to electrocardiogram, while resting and on room air.
Tables
- Table 1—
Characteristics of 246 chronic obstructive pulmonary disease patients according to usage of oxygen continuous oxygen therapy# (COT) versus noncontinuous oxygen therapy¶ (NCOT)
Subjects n COT§ NCOTƒ Age yrs 68.4±8.7 71.6±7.4 Sex female % 56.8 48.8 Current smoker % 245 16.0 20.5 Body mass index kg·m−2 228 22.0±6.0 22.0±4.6 Had outdoor activity % 242 66.0 72.3 Systemic corticosteroid % 245 50.9 44.0 FEV1 % pred value 114 29.6±10.7 30.2±10.9 Prescribed oxygen flow L·min−1 1.3±0.6 1.3±0.7 Pa,O2, mmHg+ 6.38±0.7 6.36±0.9 Pa,CO2, mmHg+ 6.78±1.2 6.49±1.4 Time spent with oxygen according to the patient h 18.5±3.4 8.2±4.8 Liquid oxygen % 245 9.3 4.8 Concentrator % 245 79.6 79.8 Mobile oxygen % 245 49.7 29.8 -
Data are presented as mean±sd unless otherwise stated
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FEV1: forced expiratory volume in one second
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Pa,O2: oxygen tension in arterial blood, COT=48.0 (5.3) mmHg, NCOT=47.8 (7.1) mmHg
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Pa,CO2: carbon dioxide tension in arterial blood, COT=51.0. (9.0) mmHg, NCOT=48.8 (10.5) mmHg
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§: n=162
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ƒ: n=84
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#: 15–24 h·day−1
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¶: <15 h·day−1
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+: 20 patients had only blood gases measured while on supplemental oxygen
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- Table 2—
Days spent in hospital and admission rates before and after starting long-term oxygen therapy (LTOT) in two groups of hypoxaemic chronic obstructive pulmonary disease patients depending on compliance with hours spent with oxygen
Variable Subjects n Before LTOT After LTOT Relative change# % p‐value All 256 Days 23.7±24.5 13.4±22.7 43.5 <0.001 Admission 2.1±1.9 1.6±2.2 23.8 <0.001 Ever admitted % 92.7 63.8 31.2 <0.001 COT 162 Days 23.1±23.9 14.2±25.7 38.5 <0.001 Admission 2.2±1.9 1.6±2.0 27.3 <0.001 Ever admitted % 94 63 33.0 <0.001 NCOT 84 Days 24.9±25.7 11.9±15.3 52.6 <0.001 Admission 2.0±1.7 1.7±2.6 15.0 0.28 Ever admitted % 89 65 27.0 0.001 -
Data are presented as mean±sd unless otherwise stated
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COT: continuous oxygen therapy (15–24 h·day−1)
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NCOT: noncontinuous oxygen therapy (<15 h·day−1)
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#: (preoxygen period-oxygen period)/preoxygen period
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- Table 3—
Days spent in hospital and admission rates before and after starting long-term oxygen therapy (LTOT) in two hypoxaemic groups of chronic obstructive pulmonary disease patients, who started oxygen therapy in the outpatient clinic, depending on compliance with hours spent with oxygen
Variable Subjects n Before LTOT After LTOT Relative change# % p‐value COT 37 Days 13.8±19.0 8.4±11.9 39.1 0.16 Admission 1.2±1.0 1.2±1.4 −8.3 0.84 Ever admitted % 76 57 25.0 0.17 NCOT 26 Days 12.2±19.6 9.2±9.9 23.8 0.46 Admission 1.1±1.6 1.1±1.1 0 1.0 Ever admitted % 65 62 4.6 1.0 -
Data are presented as mean (sd) unless otherwise stated
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COT: continuous oxygen therapy (15–24 h·day−1)
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NCOT: noncontinuous oxygen therapy (<15 h·day−1)
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#: (preoxygen period-oxygen period)/preoxygen period
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