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Efficiency of cold passover and heated humidification under continuous positive airway pressure

W.J. Randerath, J. Meier, H. Genger, U. Domanski, K‐H. Rühle
European Respiratory Journal 2002 20: 183-186; DOI: 10.1183/09031936.02.00267902
W.J. Randerath
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J. Meier
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H. Genger
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U. Domanski
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K‐H. Rühle
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    Fig. 1.—

    Schematic representation of the set-up used for the measurements. The measurement set-up comprises three modules: the impulse oscillometry for the measurement of impedance; the respiratory therapy unit; and the unit for data acquisition and processing. The subject is connected to the continuous positive airway pressure (CPAP) device and the humidifier via a nasal mask (1) and a tube system (2). The temperature of the respired air is measured within the mask (ν mask) and the hygrometer (ν hygr). Within the breathing tube there is another, small-calibre tube that transmits the pressure in the nose mask to the sensor in the CPAP device. The capacitive hygrometer for measuring the humidity in inspired and expired air (φ hygr) is located between mask and breathing tube. A valve serves to eliminate the expired carbon dioxide (3). In the impulse oscillometry unit (impulse oscillometry (IOS) device), an oscillating flow is generated and conducted, via a tube (4) and Y‐adapter (5), to the airways. The IOS device also picks up the pressure (pIOS) and flow (vIOS) signals recorded by the pneumotachograph (6) and filters out the signals produced by the oscillating flow. These signals are used to calculate the impedance. The transducer picks up all the measuring signals in the tube system and from the surroundings, and passes them, via an analogue-to-digital converter (A/D converter), to the computer (PC). pCPAP: pressure measured in the breathing tube; V′: flow measured in the breathing tube; φ amb: humidity of the ambient air; ν amb: temperature of the ambient air.

Tables

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  • Table 1—

    Humidity and water loss

    ParameterNo humidifierCold humidifierHeated humidifierp‐value
    Inspiration
     Hrel %24.0±9.134.5±10.1#53.9±13.2¶,+<0.001
     Habs mg·L−19.4±3.513.4±3.9#21.3±5.1¶,+<0.001
     υ hygrometer °C34.8±1.034.6±1.0#35.0±1.1¶,+<0.001
     υ mask °C31.1±1.431.3±1.632.4±1.7¶,+<0.001
    Expiration
     Hrel %75.5±14.479.8±10.2#82.2±8.9¶,+<0.001
     Habs mg·L−130.8±5.532.2±4.0#33.6±3.5¶,+<0.001
     υ hygrometer °C35.6±0.735.3±0.9#35.6±0.9¶,+<0.001
     υ mask °C32.4±1.132.6±1.2#33.7±1.1¶,+<0.001
     VT L0.58±0.370.59±0.370.81±1.50.42
     Bf L·min−121.9±10.221.2±10.218.9±9.90.26
     VE L·min−110.5±4.010.1±4.49.6±3.20.43
     Water loss mg·min−1226.3±49.4190.8±46.9#118.0±48.5¶,+<0.001
    Impedance of the total respiratory system
     Z 5 Hz cmH2O·L−1·s−15.7±1.86.4±2.16.7±1.8¶0.025
     R 5 Hz cmH2O·L−1·s−15.5±1.46.1±1.76.3±1.5¶0.012
     R 20 Hz cmH2O·L−1·s−15.4±0.75.3±0.75.3±0.60.62
     X 5 Hz cmH2O·L−1·s−1−1.7±1.3−2.1±1.4−2.1±1.20.21
    • Hrel: relative humidity

    • Habs: measured absolute humidity in the capacitive hygrometer

    • υ hygrometer: temperature in the hygrometer

    • υ mask: temperature in the mask

    • VT: total volume

    • Bf: breathing frequency

    • VE: minute volume

    • water loss: amount of water lost on the basis of measurements of absolute humidity in expired and inspired air

    • Z 5 Hz: impedance of the total respiratory system at an oscillation frequency of 5 Hz

    • R 5 Hz: resistance at 5 Hz

    • R 20 Hz: resistance at 20 Hz

    • X 5 Hz: reactance at 5 Hz. The p-values were determined according to the repeated-measure one-way analysis of variance (p<0.05)

    • #: cold humidifier versus no humidifier

    • +: heated humidifier versus cold humidifier

    • The post hoc significance (p<0.05)

    • ¶: heated humidifier versus no humidifier

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Efficiency of cold passover and heated humidification under continuous positive airway pressure
W.J. Randerath, J. Meier, H. Genger, U. Domanski, K‐H. Rühle
European Respiratory Journal Jul 2002, 20 (1) 183-186; DOI: 10.1183/09031936.02.00267902

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Efficiency of cold passover and heated humidification under continuous positive airway pressure
W.J. Randerath, J. Meier, H. Genger, U. Domanski, K‐H. Rühle
European Respiratory Journal Jul 2002, 20 (1) 183-186; DOI: 10.1183/09031936.02.00267902
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