Tables
- Table 1—
Characteristics of the general population weighted sample
Characteristics All M F Patients n 862 533 329 Sex M 48.5 F 51.5 Age yrs 40–49 36.1 35.3 36.8 50–59 32.4 33.2 31.8 60–69 31.5 31.6 31.4 Education High school or University 42.5 48.8 65.3 Primary school or no education 56.7 51.2 34.7 Social class (occupations)# I–II (professional/intermediate) 18.1 23.2 13.1 III (skilled nonmanual) 32.0 30.7 33.2 IV–V (manual) 49.8 40.1 53.7 Smoking behaviour Never smoker 52.7 25.4 78.3 Former Smoker 24.1 41.5 7.8 Smoker>20 pack-yrs 13.1 24.1 2.9 Smoker⩽20 pack-yrs 10.0 9.0 10.9 Respiratory diseases COPD 10.2 16.0 4.8 Asthma 3.6 3.8 3.4 Spirometric results FVC mL 3454.5±877.7 4024.7±795.5 2916.9±552.2 FEV1 mL 2578.6±726.4 2959.5±762.8 2219.5±459.7 % FVC over pred 90.3±13.8 87.0±13.8 93.5±13.1 % FEV1 over pred 89.5±16.5 84.9±17.8 93.7±13.8 FEV1/FVC % 99.2±11.1 96.6±12.0 101.6±9.4 -
Data are presented as % or mean±sd unless otherwise stated
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M: male
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F: female
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COPD: chronic obstructive pulmonary disease
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FVC: forced vital capacity
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FEV1: forced expiratory volume in one second
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#: social class based on an adaptation of the British General's Classification 26
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- Table 2—
Distribution characteristics and reliability estimates of the St George's Respiratory Questionnaire scales in the general population weighted sample
Symptoms Activity Impacts Overall Mean 9.67 13.40 4.73 8.41 sd 13.24 17.63 9.92 11.33 Observed range 0–92.8 0–100 0–79.7 0–83.4 % With worst possible score (floor) 0.0 0.3 0.0 0.0 %With best possible score (ceiling) 41.2 43.5 59.5 21.1 % With missing data# 2.0 7.6 9.6 13.2 % With missing score¶ 1.2 1.2 1.2 1.2 Cronbach's Alpha+ Probable case of COPD 0.77 0.90 0.89 0.95 Nonprobable case of COPD 0.73 0.84 0.87 0.91 Scale success rate %+ Probable case of COPD 81.3 84.4 92.3 88.0 Nonprobable case of COPD 87.5 71.9 94.2 86.0 -
n=862
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COPD: chronic obstructive pulmonary disease
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sd: standard deviation
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COPD: chronic obstructive pulmonary disease
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#: percentage of individuals with at least one missing item
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¶: percentage of individuals with missing score after handling missing data recommended by authors was applied
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+: calculated separately for probable and nonprobable cases of COPD by using Multitrait Analysis Program because it is not possible to apply weights with this package
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- Table 3—
Mean St George's Respiratory Questionnaire scale scores by demographical and clinical characteristics in the general population weighted sample
Symptoms Activity Impacts Overall Sex M 11.62 12.17 5.23 8.60 F 7.82 14.58 4.26 8.23 p‐value <0.001 0.043 0.15 0.63 Age yrs 39–49 7.97 9.33 2.69 5.78 50–59 8.74 13.48 4.55 8.19 60–69 12.54 17.95 7.23 11.61 p‐value <0.001 <0.001 <0.001 <0.001 Education High school or more 8.54 9.26 3.10 6.05 Primary school or no education 10.45 16.53 6.02 10.20 p‐value 0.03 <0.001 <0.001 <0.001 Social class (occupations)# I‐II (professional/intermediate) 9.55 9.46 2.96 6.23 III (skilled nonmanual) 7.92 10.19 3.14 6.27 IV‐V (manual) 10.29 15.93 5.64 9.79 p‐value 0.07 <0.001 <0.001 <0.001 Smoking behaviour Never smoker 7.49 13.63 4.16 7.81 Former smoker 9.58 13.19 5.50 8.69 Smoker⩽20 pack-yrs 12.99 11.58 3.38 7.76 Smoker>20 pack-yrs 16.12 14.20 6.59 10.76 p‐value <0.001 0.74 0.04 0.09 % FEV1 over pred % FEV1≥100 5.39 9.33 2.33 5.14 90⩽ % FEV1<100 8.23 9.17 2.80 6.01 80⩽ % FEV1<90 9.12 13.94 4.68 8.47 % FEV1<80 16.20 21.14 9.27 14.30 p‐value <0.001 <0.001 <0.001 <0.001 -
M: male
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F: female
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FEV1: forced expiratory volume in one second. n=862
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#: social class based on an adaptation of the British Registrar General's Classification 26
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- Table 4—
Adjusted associations between St George's Respiratory Questionnaire total score (dependent variable) and respiratory disease-related variables in the general population weighted sample
B Beta p‐value COPD 1.22 0.03 0.40 Asthma 13.91 0.18 ** % FEV1 over pred −0.13 −0.21 ** Interaction of COPD and % FEV1 over pred −0.19 −0.11 ** Smoking behaviour Never smoker Former smoker −0.08 0.00 0.91 Smoker≤20 pack-yrs 2.60 0.09 ** Smoker>20 pack-yrs 2.36 0.08 0.02 Sex 1.7 0.10 ** Age# 0.1 0.11 ** Education 1.4 0.08 0.02 Interaction of age and asthma 1.2 0.13 ** Constant 5.0 ** -
B: non standardized coefficient
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Beta: standardized coefficient
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COPD: chronic obstructive pulmonary disease
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% FEV1 over pred: % force expiratory volume in one second over predicted n=862
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#: age-centred
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Coefficient of determination: (R2)=0.19 (adjusted R2=0.18)
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**: p<0.01
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- Table 5—
Percentiles (P) and means with standard deviation (sd) of the St George's Respiratory Questionnaire (SGRQ) scale scores by age
40–49 50–59 60–69 Symptoms P5 0.0 0.0 0.0 P10 0.0 0.0 0.0 P20 0.0 0.0 0.0 P30 0.0 0.0 4.42 P40 0.0 0.0 6.82 P50/median 4.24 6.88 11.88 P60 9.46 9.55 15.16 P70 12.17 12.71 23.43 P80 16.44 16.44 29.11 P90 25.32 32.48 42.30 P95 32.60 42.79 49.93 Mean±sd 8.83±12.41 10.34±14.35 16.13±16.77 Activity P5 0.0 0.0 0.0 P10 0.0 0.0 0.0 P20 0.0 0.0 0.0 P30 0.0 0.0 0.0 P40 0.0 0.0 0.0 P50/median 0.0 5.97 11.16 P60 5.96 11.21 16.87 P70 11.21 17.32 22.60 P80 17.12 25.45 35.19 P90 23.13 36.93 47.69 P95 29.31 47.61 60.37 Mean±sd 7.76±11.15 12.69±16.59 16.28±20.41 Impacts P5 0.0 0.0 0.0 P10 0.0 0.0 0.0 P20 0.0 0.0 0.0 P30 0.0 0.0 0.0 P40 0.0 0.0 0.0 P50/median 0.0 0.0 2.30 P60 0.0 3.55 4.77 P70 0.0 5.47 7.75 P80 5.03 9.22 16.01 P90 9.48 14.60 22.84 P95 15.10 22.27 38.77 Mean±sd 2.82±6.73 4.99±8.90 8.14±4.12 Total P5 0.0 0.0 0.0 P10 0.0 0.0 0.0 P20 0.0 0.0 1.13 P30 1.65 2.08 2.08 P40 1.95 3.66 4.54 P50/median 2.72 5.48 6.98 P60 3.67 6.60 11.40 P70 6.56 8.75 14.13 P80 9.71 15.93 19.58 P90 11.65 23.34 30.64 P95 22.62 29.97 46.58 Mean±sd 5.49±7.72 8.41±10.74 12.17±14.89 -
Data are presented as SGRQ scale scores unless otherwise stated
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Males from the general population weighted sample (n=533)
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- Table 6—
Percentiles (P) and means with standard deviation (sd) of the St George's Respiratory Questionnaire (SGRQ) scale scores by age
40–49 50–59 60–69 Symptoms P5 0.0 0.0 0.0 P10 0.0 0.0 0.0 P20 0.0 0.0 0.0 P30 0.0 0.0 0.0 P40 0.0 0.0 2.32 P50/median 4.42 4.24 4.42 P60 6.75 8.80 8.13 P70 8.80 9.69 9.54 P80 12.17 14.08 14.29 P90 18.79 19.28 28.18 P95 39.21 23.76 44.79 Mean±sd 7.24±10.85 7.09±8.88 9.24±3.43 Activity P5 0.0 0.0 0.0 P10 0.0 0.0 0.0 P20 0.0 0.0 0.0 P30 0.0 0.0 0.0 P40 0.0 0.0 5.96 P50/median 5.25 6.21 12.19 P60 11.41 12.27 17.84 P70 17.12 23.28 29.31 P80 20.28 29.31 41.61 P90 35.17 35.47 47.69 P95 41.08 54.42 67.02 Mean±sd 10.81±13.99 14.29±17.43 19.36±22.62 Impacts P5 0.0 0.0 0.0 P10 0.0 0.0 0.0 P20 0.0 0.0 0.0 P30 0.0 0.0 0.0 P40 0.0 0.0 0.0 P50/median 0.0 0.0 0.0 P60 0.0 3.55 3.55 P70 1.90 3.55 4.06 P80 4.06 7.17 8.35 P90 10.67 10.64 15.43 P95 14.38 20.43 43.03 Mean±sd 2.62±5.63 4.10±7.64 6.38±13.25 Total P5 0.0 0.0 0.0 P10 0.0 0.0 0.0 P20 0.0 0.0 1.28 P30 0.80 1.78 2.17 P40 2.17 2.82 3.34 P50/median 3.75 4.44 4.26 P60 5.81 8.35 9.37 P70 7.38 10.92 13.28 P80 10.95 13.04 17.76 P90 15.40 17.93 25.96 P95 21.04 31.46 49.99 Mean±sd 6.09±7.41 7.97±9.35 11.05±14.83 -
Data are presented as SGRQ scale scores unless otherwise stated
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Females from the general population weighted sample (n=329)
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- Table 7—
Distribution characteristics of the St George’s Respiratory Questionnaire (SGRQ) scores according to sex in the subsample of chronic obstructive pulmonary diseas (COPD) patients, participants with history of asthma and healthy group
Symptoms Activity Impacts Overall Healthy individuals M (n=143) 7.63±10.83 (6.28–8.99) 7.10±10.48 (5.78–8.41) 2.36±5.02 (1.73–2.99) 4.84±6.30 (4.05–5.63) F (n=164) 6.49±9.57 (5.46–7.51) 13.13±15.73 (11.45–4.81) 3.47±7.66 (2.65–4.29) 7.14±8.83 (6.19–8.08) p‐value# 0.18 *** * *** COPD Patients M (n=275) 22.55±18.01 (18.28–26.82) 24.28±23.24 (18.75–29.81) 12.82±15.94 (9.03–6.60) 18.18±16.68 (14.21–22.15) F (n=78) 12.43±13.9 (6.59–18.27) 19.52±25.45 (8.83–30.20) 8.05±13.11 (2.54–13.55) 12.55±15.61 (6.00–19.10) p‐value# ** 0.42 0.21 0.17 Asthma M (n=39) 32.82±25.46 (20.34–45.28) 29.24±25.91 (16.56–41.92) 16.45±16.92 (8.16–24.74) 23.15±19.52 (13.6–2.70) F (n=43) 26.34±20.42 (16.19–36.49) 29.53±26.69 (15.26–43.80) 15.61±19.53 (5.89–25.33) 21.68±20.68 (11.39–1.97) p‐value# 0.44 0.98 0.89 0.84 -
Data are presented as mean±sd (95% confidence interval) unless otherwise stated
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M: male
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F: female
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COPD: chronic obstructive pulmonary disease
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#: comparison between SGRQ score from M and F
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*: p<0.05
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**: p<0.01
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p<0.001
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