Drug | Target airway site | Special considerations |
β2-agonists acute | Central-peripheral | Use O2 as driving gas unless there are concerns about CO2 retention |
Adults and children |
β2-agonists chronic | Central-peripheral | Reduce nebulization time for treatment compliance |
Adults and Children |
Anti-cholinergic | Central | Mouth piece (preferable) or tight sealing face mask |
Adults and Children | (Mouth piece for glaucoma patients) |
Corticosteroid | Central-peripheral | Minimize skin and eye exposure |
Children and adults | Mouthpiece (preferably) (or tightly sealed face mask) |
Amino-glycosides or Colomycin | Central-peripheral | Mouth piece |
Adults | Filter or exhaust exhaled gases |
Pre-treat with β-agonist when necessary |
Pentamidine | Peripheral | Mouth piece |
Adults | Pretreat with nebulized β-agonist |
Filter or exhaust exhaled gases |
Amphotericin | Central | Dilute with water not saline |
Adults | Filter or exhaust exhaled gases |
RhDNase | Central | Mouthpiece |