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Early-onset phenytoin toxicity mimicking a renopulmonary syndrome

AJ Polman, TS van der Werf, AT Tiebosch, JG Zijlstra
European Respiratory Journal 1998 11: 501-503; DOI:
AJ Polman
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TS van der Werf
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AT Tiebosch
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JG Zijlstra
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Abstract

Phenytoin is a commonly used anti-epileptic drug. Adverse reactions including fever, skin reactions and lymphadenopathy are well known but atypical reactions can also occur. A patient is described with a lag time of only 4 days between onset of phenytoin and the development of a syndrome with acute lung injury and renal failure. The symptoms mimicked a renopulmonary syndrome, and resolved completely after cessation of phenytoin and addition of steroids.

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Early-onset phenytoin toxicity mimicking a renopulmonary syndrome
AJ Polman, TS van der Werf, AT Tiebosch, JG Zijlstra
European Respiratory Journal Feb 1998, 11 (2) 501-503;

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Early-onset phenytoin toxicity mimicking a renopulmonary syndrome
AJ Polman, TS van der Werf, AT Tiebosch, JG Zijlstra
European Respiratory Journal Feb 1998, 11 (2) 501-503;
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